Difference Between Homeopathic High Potencies (Above 12c), Low Potencies (Below 12c) And Crude Drugs

On the basis of the concept of potentization as ‘molecular imprinting’ discussed in my article “DIALECTICAL HOMEOPATHY”,  homeopathic  potencies can be broadly classified into two major groups:

1.      The low potencies which contain original drug molecules (probably up to 12c)

2.      High potencies which do not contain drug molecules (probably above 12c)

(Here, the specified probability range is calculated for molecules of lowest molecular weight, using Avogadro Number. Obviously, molecules of higher molecular weight may disappear from the medium at much earlier stages of potentization. Probability range of each individual class of molecules can be calculated using their molecular weight, Avogadro Number and proportions of dilutions).

Low potencies contain original drug molecules acting as ‘Competitive Molecular Factors’(CMF) towards pathologic molecules.

High potencies contain molecular ‘imprints’ acting as ‘Counteractive Complementary Factors’(CCF) towards pathologic molecules.

A “drug” means, a sample of substance containing chemical molecules, that can interact with biological molecules, effecting deviations in biological processes. Normally, when a drug substance is introduced into an organism, the constituent drug molecules exhibit their action in any of the following ways:

1. Acting on various structural membranes, deranging their permeability.

2. Engaging in chemical reactions with various molecular substrates and metabolites inside the body.

3. Interacting with enzyme proteins, and other complex bio-molecules, thereby inactivating or  incapacitating them for biochemical processes.

4. Interaction with various structural proteins.

5. Interacting  with carrier proteins.

6. Interaction with ion channels.

7. Binding to Hormone receptors, and Neuro-transmitter receptors.

Drug molecules and their derivatives, due to their gross molecular properties, can chemically interact with biological molecules and metabolites. This phenomenon is utilized when drugs are used as allopathic medicines.

When crude drugs and low potencies are applied as ‘similimum’, the ‘drug’ molecules contained in them, if having configurational similarity to the active groups of pathological molecules, may compete with the pathological molecules in binding to the target bio-molecules, and in that process, relieve the bio-molecules from pathological inhibitions. In this case, drug molecules act as ‘competitive molecular factors’ (CMF) towards pathologic molecules. It should be understood that crude drugs and low potencies act in certain cases as therapeutic agents by this ‘competitive’ mechanism, when selected according to the principle of ‘similia similibus curentur’.

In certain situations, where there is real scarcity of certain molecules necessary for metabolism, crude substances and low potencies or mother tinctures will have to be used by their supplementary or nutritional value. This belongs to Nutritional Therapy, and should not be confused with homeopathy. Various minerals, vitamins, co-factors, micro-nutrients and amino-acid supplements belong to this category.

A more logical and scientifically viable model is required, to explain the therapeutic effects of high potency homeopathic preparations. Potentized homeopathic medicine, when introduced into the organism by any route, is carried by the body fluids, and transported to different parts of body by internal transport system. When the nano-cavities of ‘molecular imprints’ contained these preparations come in the vicinity of active groups of pathological foreign molecules, having similarity to the original ‘guest’ molecules used for imprinting, these ‘molecular imprints’ selectively bind to the pathological molecules due to configurational affinity. By this process, pathological foreign molecules are prevented from binding to biological molecules, thereby relieving the biological molecules from pathological molecular blocks. This can be conceived as some sort of ‘molecular scavenging’ or ‘entrapping’ of pathological molecules, by ‘hydrosomes’ or molecular ‘imprints’ contained in the potentized medicines.

Drugs potentized above ‘Avogadro limit’ act by an entirely different molecular mechanism. ‘Hydrosomes’ or ‘molecular imprints’ formed during potentization are configurational complementaries of original drug molecules used as ‘guest’ for potentization. These ‘molecular imprints’ act as ‘counteractive complementary factors’ (CCF) and bind to the active groups of pathologic molecules having configurational similarity to the drug molecules used for potentization. Thus the pathologic molecules are prevented from interacting with the bio-molecules, thereby relieving the molecular bocks and pathological inhibitions. The danger of drug molecules acting upon on off-target sites, with unfavorable consequences should be expected while using crude drugs and low potencies. If we want to practice real homeopathy, we should deliberately abstain from using medicinal preparations containing drug molecules.

We should also be aware of the difference between crude drugs and low potencies or triturations. Even though both preparations contain same drug molecules, their therapeutic properties are found to be different. In crude form, drug molecules are packed tightly, with their chemical bonds remaining saturated by  interacting with various other molecules or ions. Hence, they are not at all free to exhibit all their individual interactive potentials. Whereas in triturations and low potencies, the drug molecules are free or ionized, they can exhibit all their properties. Hence, pathologic and therapeutic capabilities of triturations and low potencies are much higher to crude forms of same drug, whereas drugs of toxic nature are more toxic in crude forms than dilutions, due to their high concentration of molecules. We already know that various drugs which appear  comparatively inert in their crude forms become very potent medicinal agents in triturated forms. Differences between crude Siliciea and Silice 3x, crude Lyco and Lyco 3x etc. are examples for this phenomenon.

To get an answer to the question how ‘hormesis’ works or ‘small doses’ work, we have to understand the process of ‘dilution’ in terms of ‘size’ of drug molecules. Any drug substance of animal or vegetable origin contain diverse types of drug molecules. Some complex molecules will be very ‘big’ in size, and their number in a given quantity of solution will be comparatively very small as per avogadro theory. Smaller molecules will be present in larger quantities. When we start diluting serially, larger molecules will be ‘imprinted’ into the medium, and molecules get removed from the solution in very early stages of dilution process. Smaller molecules undergo imprinting and removal at later stages only. By reaching 12 c, even the smallest molecules get imprinted and removed. That is why I say potencies above 12c contain molecular imprints only.

Obviously, lower potencies below 12c will be a mixture of small molecules as well as molecular imprints of larger molecules. We can explain hormesis, hippocrates phenomenon and low potency therapeutics from this point of view.

Author: Chandran Nambiar K C

I started practicing homeopathy in 1970, when I was 20 years old and studying for final year of BSc (Zoology) course. My interest in homeopathy happened very accidentally, through a constant relationship with a local practitioner who happened to be father of my classmate. I was a regular visitor in his clinic, where from I started reading BOERICKE MATERIA MEDICA and other homeopathic books, which helped me to cure myself my troublesome asthma that have been haunting me since my childhood days. I became a voracious reader of homeopathy. I was also deeply involved in studying marxism and dialectical materialism during my college days, which attracted me to political activities. MARXISM and HOMEOPATHY became two essential parts of my intellectual and practical life, which still continues so. Even though I joined DHMS course in a karnataka homeopathic college, I could not continue it due to my intense involvement in revolutionary political activities that resulted in jail life and a lot of criminal cases. Once that phase was over, I took a diploma in veterinary science and became a livestock inspector in animal husbandry department under govt of kerala. I have been continuing my study and practice of homeopathy all through these years. Since CCH act came into force only in 1976, and it contained provisions allowing existing practitioners to continue, my homeopathic practice went smoothly in parallel with my government job. In 1987, co-operating with some local homeopaths and social activists, I started Kannur District Homeopathic Hospital Sociey, which established a chain of hospitals and homeopathic clinics in different parts of Kannur district. After a few years I had to leave the society for some political reasons, and I established a 100 bedded well equipped homeopathic hospital in Taliparamba, employing a number of prominent homeopaths. That was ended up as a financial disaster for me due to many reasons, including my lack of skills as a money manager, and I was compelled to close down my dream project with in a short period. I lost huge money I invested, lost my reputation, and it pulled me into a debt trap. I learned a lot of valuabl lessons from this failure- about life, human psychology, relationships, and above all, about myself. I realized failure is the greatest teacher, if you are prepared learn from it. I learned how will power and determination to win will help us come back into life as a phoenix from our own ashes. I learned, one does not fail unless he stops fighting and accepts failure. My failure and the hardships that followed has moulded my personality in such a way that I can now withstand any disaster and fight back. I tell you, you will not know what life really is, unless you miserably fail at least once in your life. By this time, I left my government job also, and settled as a full time homeopathic practitioner. By this practice, I could repair my earlier financial losses, and establish well in life. It was during this period that I felt the need of developing a simple and user-friendly homeopathic software, that resulted in the evolution of SIMILIMUM, which was later upgraded into SIMILIMUM ULTRA. Similimum Ultra was well accepted by the profession, and it collected good revenues which continues even today. I stopped my practice a few years back , and concentrated in the study and research activities to evolve scientifically viable explanations to the so-called riddles of homeopathy. This unrelenting study resulted in MIT or Molecular Imprints Therapeutics, which provides a scientific and rational explanation for homeopathy. I started a homeopathic discussion group on facebook called HOMEOPATHY FOR TOTAL CURE, which has more than 35000 homeopaths as members. By this work on facebook, I could establish close relationship with many homeopaths around the world. It goes on. I could successfully convert facebook as my office and work place, from where I propagate my MIT ideas, co-ordinate my works for homeopathic community, and sell my Similimum Ultra Software. My years of hardwork in search of HOW HOMEOPATHY WORKS ultimately resulted in the publication of a book titled REDEFINING HOMEOPATHY (3000 pages, 3 volumes, hard bound, Rs 6000), in which I have compiled my articles regarding my scientific explanations of basic principles of homeopathy. These ideas are called MIT or MOLECULAR IMPRINTS THERAPEUTICS. MIT is now included in the syllabus of MD (HOM) course of prestigious DY PATIL DEEMED UNIVERSITY, PUNE, INDIA. Research department of SARADA KRISHNA HOMEOPATHIC COLLEGE, Kulashekharam, Tamilnadu, India, the only NAC accredited homeopathy college in India, has recently taken up certain reserch projects for proving the scientific explanations proposed by MIT. Based on MIT perspective of homeopathy, I had developed an MIT PROTOCOL for scientific homeopathy, and initiated a project for establishing a chain of MIT NETWORK CLINICS all over India, where MIT PROTOCOL will be practiced. More over, I have developed a whole range of 351 MIT FORMULATIONS, which are disease-specific combinations of post-avogadro diluted homeopathy drugs. NOW I AM IN 71st YEAR OF MY LIFE, AND STILL LOOKING FOR NEW HORRIZONS!

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