David Witko, in his book review published in ‘The Homoeopath’,The Society of Homoeopaths.2 Artizan Road,NorthamptonNN1 4HU,United Kingdom, on âPredictive Homeopathy Part One – Theory of Suppressionâ by Dr Prafull Vijayakar, said as follows :
“Essentially, and in outline, he charts the development of the human embryo in seven stages, from the cells and mind to the neural plate, neuro-endocrine system, mesoderm, connective tissues, endoderm, and its eventual cornpletion at the ectoderm”
“All of the organs of the body derive from these seven layers of development. To illustrate, the GI tract is formed as part of the endoderm, whilst the kidneys were formed earlier in the mesoderm”
“Vijayakar reasons that as natural embryonic growth progresses from the inside to the outside (even our bones develop this way), disease and ill-health will inevitably move in the reverse direction, i.e. from the outside (in Hering-speak) to the inside. From the ectoderm to the endoderm. From the endoderm to the mesoderm. Deeper and deeper. So if you know which parts of the body are associated with each level you can clearly see the progression of disease”.
This review of David Witko amply illustrates the essence of Vijaykarâs theory of âembryonic layersâ relating with heringâs law, on which his whole âmethodsâ and systemsâ are built up on.
Which text book of embryology says about the development of human embryo starting from âcells and mindâ? Is it vijaykarâs invention? Embryology never deals with âmindâ, but only âcellsâ.
Obviously, vijaykar wanted to make a theory seemingly scientific utilizing some concepts borrowed from genetics, but same time he wanted to establish that âmindâ is primary in the development of embryo. Hence, he added the word âmindâ along with âcellsâ while describing the initial stages of embryonic development.
According to his interpretation of âembryologyâ, development of human embryo âstartsâ from âcells and mindâ, then advances âto the neural plate, neuro-endocrine system, mesoderm, connective tissues, endoderm, and its eventual completion at the ectoderm”.
Read from Wikipedia on EMBRYONIC LAYERS:
“The gastrula with its blastopore soon develops three distinct layers of cells (the germ layers) from which all the bodily organs and tissues then develop:
the innermost layer, or endoderm, gives rise to the digestive organs, lungs and bladder; the middle layer, or mesoderm, gives rise to the muscles, skeleton and blood system; the outer layer of cells, or ectoderm, gives rise to the nervous system and skin”
â”A germ layer, occasionally referred to as a germinal epithelium, is a group of cells, formed during animal embryogenesis. Germ layers are particularly pronounced in the vertebrates; however, all animals more complex than sponges (eumetazoans and agnotozoans) produce two or three primary tissue layers (sometimes called primary germ layers). Animals with radial symmetry, like cnidarians, produce two germ layers (the ectoderm and endoderm) making them diploblastic. Animals with bilateral symmetry produce a third layer between these two layers (appropriately called the mesoderm) making them triploblastic. Germ layers eventually give rise to all of an animalâs tissues and organs through the process of organogenesis”
â”The endoderm is one of the germ layers formed during animal embryogenesis. Cells migrating inward along the archenteron form the inner layer of the gastrula, which develops into the endoderm.
The endoderm consists at first of flattened cells, which subsequently become columnar. It forms the epithelial lining of the whole of the digestive tube except part of the mouth and pharynx and the terminal part of the rectum (which are lined by involutions of the ectoderm). It also forms the lining cells of all the glands which open into the digestive tube, including those of the liver and pancreas; the epithelium of the auditory tube and tympanic cavity; the trachea, bronchi, and air cells of the lungs; the urinary bladder and part of the urethra; and the follicle lining of the thyroid gland and thymus.
The endoderm forms: the stomach, the colon, the liver, the pancreas, the urinary bladder, the lining of the urethra, the epithelial parts of trachea, the lungs, the pharynx, the thyroid, the parathyroid, and the intestines.”
â”The mesoderm germ layer forms in the embryos of triploblastic animals. During gastrulation, some of the cells migrating inward contribute to the mesoderm, an additional layer between the endoderm and the ectoderm.
The formation of a mesoderm led to the development of a coelom. Organs formed inside a coelom can freely move, grow, and develop independently of the body wall while fluid cushions and protects them from shocks.
The mesoderm forms: skeletal muscle, the skeleton, the dermis of skin, connective tissue, the urogenital system, the heart, blood (lymph cells), the kidney, and the spleen.”
â”The ectoderm is the start of a tissue that covers the body surfaces. It emerges first and forms from the outermost of the germ layers.
The ectoderm forms: the central nervous system, the lens of the eye, cranial and sensory, the ganglia and nerves, pigment cells, head connective tissues, the epidermis, hair, and mammary glands.
Because of its great importance, the neural crest is sometimes considered a fourth germ layer. It is, however, derived from the ectoderm”
âThe “ectoderm” is one of the three primary germ cell layers in the very early embryo. The other two layers are the mesoderm (middle layer) and endoderm (inside layer), with the ectoderm as the most exterior layer. It emerges first and forms from the outer layer of germ cells. Generally speaking, the ectoderm differentiates to form the nervous system (spine, peripheral nerves and brain), tooth enamel and the epidermis (the outer part of integument). It also forms the lining of mouth, anus, nostrils, sweat glands, hair and nailsâ.
âIn vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neural crest, and neural tube. The latter two are known as neuroectoderm.ââ
Please note this point: The fertilized ovum âdevelops three distinct layers of cells (the germ layers) from which all the bodily organs and tissues then develop: the innermost layer, or endoderm, gives rise to the digestive organs, lungs and bladder; the middle layer, or mesoderm, gives rise to the muscles, skeleton and blood system; the outer layer of cells, or ectoderm, gives rise to the nervous system and skin”
It is obvious that brain and nervous system develops from âectodermâ layer. It is the âoutermostâ layer of embryo, not âinnermostâ. The theory of vijaykar that âbrain and mindâ belongs to innermost embryonic layer is pure nonsense. They develop from âoutermostâ embryonic layer called âectodermâ, from which organs such as skin and hair also develops. His theory that embryonic development âstartsâ with âmindâ and âendsâ with âectodermâ has nothing to do with embryology, except that he plays with some terms used in embryology.
David Witko says: “Vijayakar reasons that as natural embryonic growth progresses from the inside to the outside, disease and ill-health will inevitably move in the reverse direction, i.e. from the outside to the inside”.
This is the most fundamental âreasoningâ of vijaykar, which he utilizes to build a common ground with âhering laws regarding directions of cureâ on which his whole âtheoretical system is built upon.
We already saw that the concept âdirection of embryonic developmentâ on which his âreasoningâ is itself totally baseless. Embryonic development does not start from âinnerâ organs of endoderm and âcompleteâ with âouterâ organs of ectodermâ as vijaykar tries to establish.
Even if the direction of âembryonic developmentâ was from âinner layer to outer layerâ, what is the logic behind his âreasoningâ that âdisease and ill-health will inevitably move in the reverse direction, i.e. from the outside to the inside”?
Most funny thing regarding this âreasoningâ is that it goes against the fundamental concept of disease accepted by âclassical homeopathyâ that âdiseases originate in the level of vital forceâ. Vijaykar says âdirection od disease is from âoutermost layerâ to âinnermost layerâ. Should we understand that âvital forceâ belongs to âoutermostâ layer of organism according to the interpretation of Vijayakar? Both cannot be right by any way. Either vijaykar should say that diseases originate in âvital forceâ which is the âinnermost layerâ, or he should say disease start in the âoutermostâ layer, that is skin and hair.
Since vijaykar has gone totally wrong and self contradicting in his understanding of embryonic layers and âdirection of embryonic developmentâ, his explanation of âhering lawâ based on his âreasoningâ is pure nonsense.
âCurative processes happen in a direction just reverse to disease processesâ-Â that is the sum total of Heringâs observations regarding âdirections of cureâ.
The four âlawsâ now known as âherings lawsâ are actually the working examples he used to demonstrate this fundamental observation.
It was the later âinterpretersâ who actually converted these four âworkingâ examples into âfundamental lawsâ of homeopathic cure. They understood and applied these âlawsâ in a mechanical way. They taught homeopaths to consider âhering lawsâ regarding âdirections of cureâ as one of the âfundamental lawsâ of homeopathy, similar to âsimilia similibus curenturâ. They made homeopaths believe that drug effects that do not agree with these âlawsâ cannot be considered âcurativeâ, and are âsuppressiveâ. There are some modern streams of homeopathic practice which rely more upon âhering lawsâ than âsimilia similibu curenturâ in their methods of therapeutic applications.
Actually, Hahnemann did not seriously work upon those aspects of curative processes which we call âdirections of cureâ, or considered it a decisive factor in homeopathic therapeutics. He was more concerned about âmismsâ in the management of âchronic diseasesâ, where as Hering did not consider âmiasmsâ at all.
Some modern âtheoreticiansâ have come with new theories by combining âhering lawsâ and theory of miasms, also mixing up with terms of âgeneticsâ and âembryologyâ which they propagate as the âonlyâ correct understanding of homeopathy
Following are the four working âexamplesâ hering used to demonstrate his observation that âCurative processes happen in a direction just reverse to disease processesâ, and later considered as âHering laws of direction of cureâ:
In a genuine curative process,
- Symptoms should disappear in the reverse chronological order of their appearance in disease.
- Symptoms should travel from internal parts of body to external parts
- Symptoms should travel from more vital organs to less vital organs.
- Symptoms should travel from âupperâ parts of the body to âlowerâ parts.
According to those who consider these as the âfundamental law of cureâ, any drug effect that happen not in accordance with above laws are âsuppressiveâ, and hence not âcurativeâ.
âDisease processes and curative processes always happen in reverse directionsâ is the fundamental observation hering actually tried to establish regarding âdirections of disease and cureâ.
According to heringâs observation, natural disease processes always advances from lower parts of the body to upper parts, from less vital to more vital organs and from external to internal organs. More over, all these disease processes advance in a chronological order.
Logically, Heringâs observations only mean that âall genuine âcurative processesâ should happen in a direction just reverse to disease processesâ.
Over-extending and mechanical application of âherings lawsâ without understanding their exact premises and scientific meaning may lead to grave errors regarding interpretation of curative processes and drug effects.
This phenomenon could be explained in the light of modern scientific understanding of âcascading of pathological molecular inhibitionsâ and complex dynamics of âbio-molecular feed back mechanismsâ.
To understand this explanation, one has to equip himself with at least a working knowledge regarding the concepts of modern biochemistry regarding the bio-molecular inhibitions involved in pathology and therapeutics.
Except those diseases which are purely due to errors in genetic substances, and those diseases which are due to genuine deficiency of building materials of biological molecules, all other diseases are considered to be caused by âmolecular inhibitionsâ. Pathogenic molecules of endogenous or exogenous origin bind to some biological molecules in the organism, causing âmolecular inhibitionsâ which lead to pathological derangement in associated biochemical pathways. These pathogenic molecules may be of infectious, environmental, nutritional, metabolic, drug-induced, miasmatic or any other origin. Derangements in biochemical pathways are expressed through diverse groups of subjective and objective symptoms. This is the fundamental biochemistry of pathology.
Molecular inhibitions happening in a biological molecule due to the binding of a pathogenic molecule initiates a complex process of âcascading of molecular errorsâ and âbio-feedback mechanismsâ in the organism. Errors happening in a particular biochemical pathway leads to errors in another pathway which is dependant on the first pathway for regular supply of metabolites, which further lead to errors in another pathway. This âcascading of molecular errorsâ happens through successive stages, which is expressed through new subjective and objective symptoms. This âcascadingâ is behind what we call âadvancing of diseaseâ into new systems and organs, exhibiting ever new groups of associated symptoms. For an observer, this cascading appears in the form of âtraveling of diseaseâ from one system into another. Along with these âcascadingâ of molecular errors, there happens a series of activation and shutting down of complex âbio-molecular feedbackâ mechanisms also. The phenomenon of âadvancing of diseasesâ should be studied in this scientific perspective of modern biochemistry.
When a molecular inhibition happens in some biological molecule âAâ due to binding of a pathogenic molecule âaâ, it actually stops or decreases some essential molecular conversions that are essential part of a complex biochemical pathway P. If âGâ is the normal ligand of âAâ, and âgâ is the product of biochemical interaction involving âAâ, the result of this molecular inhibition is that âGâ accumulates on one side, and âgâ is not available for the next stage of molecular processes. Accumulating âPâ may induce a feedback mechanism leading to reduction or stoppage its production itself, or may move to other parts of organism and bind to unwanted molecular targets, initiation a new stream of pathological derangement.
Obviously, âtravelingâ of disease or âadvancingâ of disease happens through cascading of molecular errors in various biochemical pathways. Some disease processes may âtravelâ from âexternalâ to internal organs, some from âlower partsâ to upper parts, some from âless vitalâ parts to âmore vitalâ parts. All these âtravelingâ is basically decided by the involved biochemical pathways. It would be wrong to generalize these observations in such a way that âall diseases travel from exterior to interior, lower parts to higher parts, and less vital to more vital partsâ. It is also wrong to generalize in such a way that âcurative process always travel from interior to exterior, above downwards, and from vital to less vital partsâ. This is mechanical understanding and application of heringâs observations.
Actually, curative processes happens in a direction opposite to the direction of disease process. That depends upon the biochemical pathways involved and the exact dynamics of cascading of molecular inhibitions. Its dynamics is very complex, and should not be interpreted and applied in a mechanistic way. When âmolecular inhibitionsâ underlying the disease processes are systematically removed using molecular imprints, the curative process also would take place in the reverse direction of disease processes.
To sum up, Heringâs observations regarding a âdirections of disease and cureâ is a valuable one, but it should be studied in the light of modern biochemistry.
âCurative processes happen in a direction just reverse to disease processesâ-Â that is the sum total of Heringâs observations regarding âdirections of cureâ.
Vijaykar totally failed to comprehend the biochemistry involved in homeopathic therapeutics, and hence could not interpret the âdirections of disease and cureâ in relation with the interactions of biochemical pathways. In the absence of essential scientific knowledge, he only tried to make his theories appear âscientificâ by utilizing some terms from embryology and genetics. Playing with scientific vocabulary, he was successful in marketing his theories well among the âscience-starvedâ sections of homeopathic community.
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