Anybody with basic scientific awareness knows well that not a single molecule of a drug substance will remain in a sample of solution once it is diluted above Avogadro number.
But homeopathy uses dilutions that are much above this limit, and claims it is working. Moreover, homeopaths talk a lot of unscientific, superstitious and nonsense metaphysical theories such as immaterial vital force and dynamic energy, hoping to provide explanations. This is the main reason why scientific-minded people say homeopathy contradicts existing scientific knowledge, and it is totally unacceptable. This stand is understandable.
In order to establish homeopathy as a genuine scientific medical system, first of all, we should be capable of providing a scientifically viable explanation for the fundamental principle “similia similibus curentur”, in a way fitting to the advanced knowledge provided by modern life sciences, including biochemistry, molecular level pathology as well as pharmacodynamics.
Secondly, we should be capable of providing a rational and scientific answer to the question how the specific medicinal properties of chemical molecules contained in drug substances could be transmitted to and preserved a medium of water and ethanol in its ‘reverse order’, even after removing all the drug molecules from the medium.
Thirdly, it is highly essential that homeopathy should be capable of answering the question, what are “material” active principles contained in post-avogadro diluted preparations that could carry the medicinal properties of drug substances and work as therapeutic agents, whereas it is very much obvious that it will not contain even a single molecule of original drug molecules.
Lastly and most importantly, homeopathy should explain what is the exact biological mechanism by which the active principles of post-avogadro diluted drugs, whatever it be, act upon the biological molecules and produce a therapeutic effect, in a way fitting to the advanced scientific knowledge regarding the kinetics of modern pharmacodynamics.
Homeopathy could be established and accepted as a medical science only when we succeed in providing answers and proofs for these basic scientific questions. Until that happens, it is natural that people with scientific temper will go on asking such rational questions.