Implications of Luc Montagnier’s Works Upon Scientific Understanding of Ultra Dilutions
Luc Antoine Montagnier is a French virologist and joint recipient with Françoise Barré-Sinoussi and Harald zur Hausen of the 2008 Nobel Prize in Physiology or Medicine, for his discovery of the human immunodeficiency virus (HIV).
In 2009 he published a paper regarding detection of electromagnetic signals from bacterial DNA (M. pirum and E. coli) in water that had been prepared using agitation and high dilutions, and similar research on electromagnetic detection of HIV DNA in the blood of AIDS patients treated by anti-retroviral therapy. While homeopaths claim his research as support for homeopathy, many scientists have greeted it with scorn and harsh criticism. Because the research used high dilutions, homeopaths claimed it supported homeopathy, even though it didn’t mention homeopathy or use ultra-high dilutions.
He was also questioned on his beliefs about homeopathy, to which he replied: “I can’t say that homeopathy is right in everything. What I can say now is that the high dilutions are right. High dilutions of something are not nothing. They are water structures which mimic the original molecules.”
He did admit that he wasn’t working with the very high dilution levels normally used in homeopathy: “We ﬁnd that with DNA, we cannot work at the extremely high dilutions used in homeopathy; we cannot go further than a 10-18 dilution, or we lose the signal. But even at 10-18, you can calculate that there is not a single molecule of DNA left. And yet we detect a signal.”
Luc Montagnier’s observation that ‘high dilutions’ contain “water structures which mimic the original molecules.” is very important for homeopathy. But, he never tried to explain the exact molecular mechanism by which this ‘mimicking’ happens, and more important, did not take up the task of explaining the dynamics of homeopathic therapeutics involved in ‘simila similibus curentur’.
What happened was that people interested in ‘ultra-scientific’ and ‘dynamic’ interpretation of homeopathy actually hijacked his theory. Only because he said he could detect ‘electromagnetic signals’ showing the presence of ‘molecular memory of dugs’ in high dilutions, these theoreticians used it to justify their pseudoscientific concepts of ‘resonance’, ‘vibrations’, frequencies’, ‘drug transmissions’, ‘radionics’, ‘drug teleportation’ and the like they use in explaining homeopathy.
Luc Montagnier’s limitation lies in the fact that he could not understand the concept of ‘molecular imprinting’. If he could have explained the phenomenon he observed in terms of ‘molecular imprinting’, instead of ‘mimicking’ and ‘vibrations’, the situation would have been entirely different. If he could have gone a bit forward and explained WATER CLUSTERS acting as the source of ‘electromagnetic signals’ as ‘molecular imprints’, he could have avoided the ‘occult’ homeopaths and ‘spiritual homeopaths hijacking and misusing his statements for their ulterior motives.
To be more exact, Montagnier should have said: “high dilutions of something are not nothing- hey are water structures which are ‘three-dimensional negative molecular imprints’ of original molecules.” Not mimics’ . That could have made a big difference for homeopathy.
According to Luc Montaigner, the ‘water structures’ formed in high dilutions are ‘mimics’ of original molecules. But in terms of modern molecular imprinting technology, ‘molecular imprints’ are 3d structures with configurations just complementary to original molecules. If we consider original molecules as ‘keys’, montaigner consider ‘nanostructures’ as duplicate keys. According to my concept, ‘molecular imprints’ are ‘artificial key holes’ that could act as ‘artificial binding sites’ for original keys or keys similar to them. Molecular imprints bind to the pathogenic molecules due to complementary configuration, exactly like a key hole binds to a key. Molecular imprinting produces artificial ‘key-holes’, not ‘duplicate keys.’ Once we understand this difference in perceptions, it would be easy for us to understand ‘similia similibus curentur’ scientifically.
Only ‘three-dimensional negative molecular imprints’ can explain the molecular mechanism of homeopathic therapeutics, where potentized drugs are not acting similar to original drug molecules, but just as exact ‘opposites’. That is ‘similia similibus curentur’.
“I can’t say that homeopathy is right in everything. What I can say now is that the high dilutions are right. High dilutions of something are not nothing. They are water structures which mimic the original molecules.”
Bnveneste also, similar to Montagnier, perceived potentized drugs as “water structures which mimic the original molecules”. Both of them were wrong.
I say, potentized drugs are “water structures which are ‘three-dimensional negative molecular imprints’ of original molecules.” I am trying to explain homeopathy on the basis of this “molecular imprint” concept.
In his article ‘DNA Between Physics and Biology’, Luc Montaigner explains about his famous experiment in which he used ‘nano-water structures’ mimicking specific dna fragments contained ‘ultra dilutions’ to induce in vitro synthesize of similar dna fragments using nucleotide primers and polymerase enzyme as follows:
“Now we undertake the most critical step: to investigate the specificity of the induced water nanostructures by recreating from them the DNA sequence. For this we add to the tube of signalized water all the ingredients to synthesize the DNA by polymerase chain reaction (nucleotides, primers, polymerase). The amplification was performed under classical conditions (35 cycles) in a thermocycler. The DNA produced was then submitted to electrophoresis in an agarose gel. Indeed, a DNA band of the expected size of the original LTR fragment was detected . We further verified that this DNA had a sequence identical or close to identical to the original DNA sequence of the LTR. In fact, it was 98% identical (2 nucleotide difference) out of 104. This experiment was found to be highly reproducible (12 out of 12) and was also repeated with another DNA sequence from a bacterium, Borrelia burgdorferi, the agent of Lyme disease. It clearly shows that the water nanostructures and their electromagnetic resonance can faithfully perpetuate DNA information…”
Instead of this vague theorizing about “water nanostructures and their electromagnetic resonance can faithfully perpetuate DNA information”, he could have explained this phenomenon in a more rational way, if he could understand the concept of ‘molecular imprinting’ involved in high dilutions.
According to my view, it is not the ‘electro magnetic resonance’ or ‘mimicking’ that induced dna synthesis in his experiments. Actually, the high dilutions of dna solutions he preapared contained ‘molecular imprints’ of specific dna fragments. When he added nucleotide primers and polymerase enzymes into this molecular imprinted water medium, molecular imprints could have held the nucleotide primers in the correct sequence and position similar to that of original dna fragment. Then, the polymeraze enzyme could have connected these primers to form dna molecules exactly similar to original one. Here, ‘molecular imprints’ acted as ‘templates’, and helped in arranging nucleotide primers in correct sequence by binding to them, due to the specific configurational affinity.
Since he had no any idea of molecular imprinting, he tried to explain this phenomenon in terms of ‘electromagnetic resonance’, which led to ultra-scientific interpretations. This limitations helped the ‘energy medicine’ theorists to hijack and misuse the works of luc montaigner.