When physician tries to resolve only the most troublesome and immediate PARTICULAR complaints of a case, disregarding its CONSTITUTIONAL aspects, it is an ACUTE approach.
When he tries to resolve the same case with full regard to its CONSTITUTIONAL as well as PARTICULAR aspects, it is a CHRONIC approach. Way of case taking, collection of symptoms, heirachy of symptoms, weightage of symptoms, way of selecting drugs, dosage, mode of administration- every thing changes depending up on whether physician approaches the case as CHRONIC or ACUTE.
If you decide to you target only the most distressing PARTICULAR COMPLAINTS that represent some ABNORMAL conditions, you can work out a case by ACUTE approach. In this approach, you have to collect all the most prominent ABNORMAL BASIC SYMPTOMS you want to relieve, along with their accessories such as LOCATION, SENSATIONS, CAUSATIONS, PRESENTATION, MODALITIES, CONCOMITANTS etc. Add each BASIC symptom with its characteristic ACCESSORIES, to make a COMPLETE HOMEOPATHIC SYMPTOM, and find a similimum for it. If you get more than one COMPLETE SYMPTOM, you may get different similimum for each. Prescribe them.
If you decide to work out the case for a TOTAL CURE by CHRONIC approach, over and above the above mentioned BASIC SYMPTOMS and their ACCESSORY symptoms, collect all ABNORMAL symptoms related with the WHOLE PERSON, such as Physical generals, Mentals, Miasms, Family History, Chronology of complaints, Vaccinations, Previous diseases, Miasms, Allergies, Food habits, Addictions, Thermals, Dreams, Facial expressions, Gestures, Emotional background, Occupation, Working environment, Family relations, Personal relationships, Living environment- everything have to be collected if you are going to work out a case by CHRONIC approach. Repertorize by any of the conventional repertorization methods and find appropriate similimum.
When working with CHRONIC approach, I prefer to arrange symptoms into different SYMPTOM GROUPS such as PHYSICAL GENERALS, MENTALS, and different categories of PARTICULARS. Then I would find similimum for each group separately. If all groups cover same similimum, I would prescribe it. If different symptom groups indicate different similimum, I go for MULTIPLE drug prescriptions to ensure a TOTAL CURE of the PATIENT.
In ACUTE approach, ‘previous history’ is more or less ignored. Diseases are dealt with a similimum selected on on CAUSATION- LOCATION- PRESENTATION- SENSATIONS- MODALITIES- CONCOMITANTS.
In CHRONIC approach, ‘previous history’ of disease evolution is very important. If an acute complaint has a long PREVIOUS HISTORY, CHRONIC approach will be more suitable. To deal with CHRONIC approach, we will have to consider PHYSICAL GENERALS, MENTALS and HISTORY over and above CAUSATION- LOCATION-PRESENTATION- SENSATIONS- MODALITIES- CONCOMITANTS while making prescriptions. HISTORY includes genetics, previous infections, family history, vaccinations, emotional history, occupational history, environmental history etc etc.
MIASMS or ‘persistent off target actions of antibodies generated against infectious agents and alien proteins’ are the MAJOR factor to be considered in CHRONIC approach. Auto-immune diseases, prion diseases, proteinopathies or deformed protein diseases, vaccination diseases, immune-related diseases, ontological diseases – all these diseases belonging to this class of MIASMATIC diseases warrants a CHRONIC approach.
GENETIC DISEASES originating from aberrations in inherited GENETIC SUBSTANCE or CHROMOSOMES belong to a separate class of diseases, which cannot be treated with homeopathic drugs. Homeopathic drugs cannot ‘produce’ missing genes any way.
Diseases originating from errors in GENETIC EXPRESSIONS are different from genetic diseases. Errors in genetic expressions are caused by ERRORS IN ENZYME SYSTEMS associated with the biochemical processes involved in protein synthesis using genetic codes. These errors may be either MIASMATIC or NON-MIASMATIC in origin. We can cure such diseases if dealt with CHRONIC approach effectively.
GENETIC DISEASES does not mean FROM BIRTH. ‘From birth’ is CONGENITAL DISEASE. Genetic diseases are diseases due to errors in inherited genetic substance or chromosomes
All congenital diseases need not be genetic. All genetic diseases need not appear as congenital. Genetic diseases are inherited. But all inherited diseases are not genetic. There is epigenetic inheritance also.
Epigenetics is the study of changes in gene expression or cellular phenotype, caused by mechanisms other than changes in the underlying DNA sequence. They are seen to be inherited.
EPIGENETICS refers to functionally relevant modifications to the genome that do not involve a change in the nucleotide sequence. Examples of such modifications are DNA methylation and histone modification, both of which serve to regulate gene expression without altering the underlying DNA sequence. Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA. These changes may remain through cell divisions for the remainder of the cell’s life and may also last for multiple generations. However, there is no change in the underlying DNA sequence of the organism; instead, non-genetic factors cause the organism’s genes to behave or “express themselves” differently.
Epigenetics involves the study of CHANGES in GENETIC SUBSTANCE happening without any change in DNA sequence. These changes are caused through DNA METHYLATION and HISTONE MODIFICATION. They are normal processes that facilitates GENETIC EXPRESSION. Some endogenous factors can influence the METHYL TRANSFERASE enzymes involved in this process, there by producing ABNORMAL methylation of certain particular genes resulting in their silencing or over activation. These ABNORMAL epigenetic changes play a role in cancers, and many psychological problems. NEUROCHEMICALS generated as part of emotional processes also can affect the ENZYMES involved in methylation of DNA and cause errors in genetic expressions. That is the way EMOTIONS cause various disease conditions.When epigenetic changes happen in SPERMS or OVUM, such changes will be inherited to the next generation.
EPIGENETIC processes play a big role in DISEASES that are not GENETIC, but related with errors in GENETIC EXPRESSION. Epigenetics can explain why persons of similar genetic inheritance behave differently, or get diseases differently. EPIGENETICS will help us in understanding the BIOCHEMISTRY of PSYCHOSOMATIC DISEASES, and also how the EMOTIONAL DISTURBANCES happened in parents affect the offsprings
WIKIPEDIA SAYS: “EPIGENETICS is the study of functionally relevant modifications to the genome that do not involve a change in the nucleotide sequence. Examples of such modifications are DNA methylation and histone modification, both of which serve to regulate gene expression without altering the underlying DNA sequence. Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA. These changes may remain through cell divisions for the remainder of the cell’s life and may also last for multiple generations. However, there is no change in the underlying DNA sequence of the organism; instead, non-genetic factors cause the organism’s genes to behave (or “express themselves”) differently. There are objections to the use of the term epigenetic to describe chemical modification of histone, since it remains unclear whether or not histone modifications are heritable.
One example of epigenetic changes in eukaryotic biology is the process of cellular differentiation. During morphogenesis, totipotent stem cells become the various pluripotent cell lines of the embryo, which in turn become fully differentiated cells. In other words, a single fertilized egg cell – the zygote – changes into the many cell types including neurons, muscle cells, epithelium, endothelium of blood vessels, etc. as it continues to divide. It does so by activating some genes while inhibiting others.
The epigenetic code can be multidimensional in nature. It could include any of the three major cellular macromolecucles; namely, DNA (code independent), RNA, and/or protein.