MIT HYPOTHESIS- How To Prove It According To Scientific Methods?

According to MIT HYPOTHESIS, active principles of post-avogadro  potentized drugs are MOLECULAR IMPRINTS of individual chemical molecules contained in the drug substances used for potentization.

As per this hypothesis, ‘molecular imprints’ are hydrogen-bonded supramolecular formations of  water-ethyl alcohol molecules, into which the three-dimensional  spacial conformations of drug molecules are imprinted or engraved as nanocavities, through a process of host-guest interactions or  MOLECULAR IMPRINTING  involved in the process of potentization.

These ‘molecular imprints’ can act as artificial binding sites or key holes for binding to the original drug molecules as well as any pathogenic molecule conformationally similar to the drug molecules.

When applied as therapeutic agent, these molecular imprints specifically bind to the pathogenic molecules having conformational affinity, thereby deactivating them and relieving the biological molecules from pathological molecular inhibitions.

This is the biological mechanism of homeopathic cure as proposed by MIT HYPOTHESIS.

Actually, the biological mechanism of cure proposed in this model is not a new idea. It is well accepted in modern molecular medicine and pharmacology, and is the basis of target-specific drug designing techniques currently very popular in pharmaceutical researches. There remains nothing to be proved on this idea.

Molecular imprinting in polymers (MIP) also is recently a very popular research area, a technique used in developing artificial binding sites in polymer matrices through a process of molecular level ‘host-guest’ interactions. These ‘molecular imprinted polymers’ are currently utilized in various laboratory procedures as molecular binding and filtering agents.

What I have been trying to do by MIT hypothesis is to adapt these well-accepted scientific concepts into the theoretical frame work of homeopathy, so that a scientific model could be developed to explain the biological mechanism of homeopathic  cure. MIT hypothesis explains homeopathic potentization in terms of ‘molecular imprinting in water’, and homeopathic cure in terms of removal of molecular inhibitions.

Only thing remaining to be scientifically proved is that potentized homeopathic drugs contain ‘molecular imprints’. It raises the question whether water-ethyl alcohol mixture can act as a medium for molecular imprinting, similar to polymers. Various studies regarding supra molecular properties of water indicate some ‘polymer-like’ properties of water and formations of hydrogen-bonded nanoclusters in a micro-environment, which obviously opens up possibilities of molecular imprinting in water-ethyl alcohol matrix.


a) high dilution drugs really work as curative agents when applied according to indications,

b) high dilution drugs works not only in living bodies, but also up on ‘in vitro’ biological samples,

c) high dilution drugs cannot interfere or prevent the normal interactions between biological molecules and their natural ligands,

d) high dilution drugs can antidote the biological effects of same drugs used in crude or molecular forms,

e) biological properties of high dilution drugs are different or reverse to those of same drugs in molecular forms,

f) high dilution drugs do not contain original drug molecules,

g) high dilution drugs and unpotentized water-alcohol mixture are similar in their chemical structure and properties,

h) high dilution drugs differ from unpotentized water-alcohol mixture regarding physical properties and various physical parameters,

i) high dilution drugs  differ from unpotentized water-alcohol mixture regarding supra-molecular arrangements by formation of nano-clusters as could be observed by difference in spectroscopic studies,

j) Medicinal properties of high dilution drugs could be destroyed by applying strong heat, electric currents or other forms of electromagnetic energy, which will also change the characteristic physical properties of those potentized drugs,


Author: Chandran Nambiar K C

I started practicing homeopathy in 1970, when I was 20 years old and studying for final year of BSc (Zoology) course. My interest in homeopathy happened very accidentally, through a constant relationship with a local practitioner who happened to be father of my classmate. I was a regular visitor in his clinic, where from I started reading BOERICKE MATERIA MEDICA and other homeopathic books, which helped me to cure myself my troublesome asthma that have been haunting me since my childhood days. I became a voracious reader of homeopathy. I was also deeply involved in studying marxism and dialectical materialism during my college days, which attracted me to political activities. MARXISM and HOMEOPATHY became two essential parts of my intellectual and practical life, which still continues so. Even though I joined DHMS course in a karnataka homeopathic college, I could not continue it due to my intense involvement in revolutionary political activities that resulted in jail life and a lot of criminal cases. Once that phase was over, I took a diploma in veterinary science and became a livestock inspector in animal husbandry department under govt of kerala. I have been continuing my study and practice of homeopathy all through these years. Since CCH act came into force only in 1976, and it contained provisions allowing existing practitioners to continue, my homeopathic practice went smoothly in parallel with my government job. In 1987, co-operating with some local homeopaths and social activists, I started Kannur District Homeopathic Hospital Sociey, which established a chain of hospitals and homeopathic clinics in different parts of Kannur district. After a few years I had to leave the society for some political reasons, and I established a 100 bedded well equipped homeopathic hospital in Taliparamba, employing a number of prominent homeopaths. That was ended up as a financial disaster for me due to many reasons, including my lack of skills as a money manager, and I was compelled to close down my dream project with in a short period. I lost huge money I invested, lost my reputation, and it pulled me into a debt trap. I learned a lot of valuabl lessons from this failure- about life, human psychology, relationships, and above all, about myself. I realized failure is the greatest teacher, if you are prepared learn from it. I learned how will power and determination to win will help us come back into life as a phoenix from our own ashes. I learned, one does not fail unless he stops fighting and accepts failure. My failure and the hardships that followed has moulded my personality in such a way that I can now withstand any disaster and fight back. I tell you, you will not know what life really is, unless you miserably fail at least once in your life. By this time, I left my government job also, and settled as a full time homeopathic practitioner. By this practice, I could repair my earlier financial losses, and establish well in life. It was during this period that I felt the need of developing a simple and user-friendly homeopathic software, that resulted in the evolution of SIMILIMUM, which was later upgraded into SIMILIMUM ULTRA. Similimum Ultra was well accepted by the profession, and it collected good revenues which continues even today. I stopped my practice a few years back , and concentrated in the study and research activities to evolve scientifically viable explanations to the so-called riddles of homeopathy. This unrelenting study resulted in MIT or Molecular Imprints Therapeutics, which provides a scientific and rational explanation for homeopathy. I started a homeopathic discussion group on facebook called HOMEOPATHY FOR TOTAL CURE, which has more than 35000 homeopaths as members. By this work on facebook, I could establish close relationship with many homeopaths around the world. It goes on. I could successfully convert facebook as my office and work place, from where I propagate my MIT ideas, co-ordinate my works for homeopathic community, and sell my Similimum Ultra Software. My years of hardwork in search of HOW HOMEOPATHY WORKS ultimately resulted in the publication of a book titled REDEFINING HOMEOPATHY (3000 pages, 3 volumes, hard bound, Rs 6000), in which I have compiled my articles regarding my scientific explanations of basic principles of homeopathy. These ideas are called MIT or MOLECULAR IMPRINTS THERAPEUTICS. MIT is now included in the syllabus of MD (HOM) course of prestigious DY PATIL DEEMED UNIVERSITY, PUNE, INDIA. Research department of SARADA KRISHNA HOMEOPATHIC COLLEGE, Kulashekharam, Tamilnadu, India, the only NAC accredited homeopathy college in India, has recently taken up certain reserch projects for proving the scientific explanations proposed by MIT. Based on MIT perspective of homeopathy, I had developed an MIT PROTOCOL for scientific homeopathy, and initiated a project for establishing a chain of MIT NETWORK CLINICS all over India, where MIT PROTOCOL will be practiced. More over, I have developed a whole range of 351 MIT FORMULATIONS, which are disease-specific combinations of post-avogadro diluted homeopathy drugs. NOW I AM IN 71st YEAR OF MY LIFE, AND STILL LOOKING FOR NEW HORRIZONS!

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