Possibilities of potentized homeopathic medicines interacting with genetic substance in the organism and producing harmful genetic effects is a subject of much concern, speculations and controversy among homeopaths. Such controversies arise from the lack of sufficient understanding regarding the active principles contained in potentized medicines, and their exact mechanism of action in the living system.
With our new scientific understanding of potentization as a process of molecular imprinting, we are now in a better position to answer these questions satisfactorily. Since, molecular imprints contained in the potentized homeopathic preparations cannot successfully compete with natural ligands in binding with their target molecules, there is no possibility of potentized homeopathic medicines producing any effect on genetic material that may result in mutations.
Molecular imprints contained in the potentized homeopathic preparations bind to ligands or biological molecules merely due to their complementary configurations without any charge affinity, whereas natural ligands bind to their biological target molecules in capacity of their appropriate spacial configurations as well as charge affinities. So, the bindings of molecular imprints with biological molecules or their ligands will be very temporary and cannot stay long. Such bindings of molecular imprints cannot replace the natural ligand-target interactions happening as part of vital processes.
Molecular imprints can not compete with natural ligands in binding to their natural biological targets. Hence it is obvious that potentized homeopathic preparations cannot interfere in biological ‘ligand-target’ processes such as ‘substrate-enzyme’, ‘antigens-antibodies’, ‘signal-receptor’ etc. As such, chances of potentized homeopathic medicines acting as pathological agents are very rare even if used indiscriminately. Molecular imprints can interfere only in interactions between pathogenic molecules and biological molecules, as well as off-target bindings of ligands with biological molecules, where only conformational affinity is involved. Obviously, molecular imprints can act upon only the molecular blocks created by exogenous or endogenous foreign pathological molecules.
At the same time, these molecular imprints can effectively deal with the pathogenic actions of deformed proteins that may result from genetic errors, thereby preventing them from creating cascading of pathological molecular blocks at various targets. As such, homeopathic medicines can play a great role even in the treatment of certain diseases of genetic origin, at least as palliatives.
More over, potentized homeopathic medicines can safeguard genetic material from dangerous mutations that may be caused the by inhibitory actions of endogenous or exogenous pathogenic agents such as toxic drugs, heavy metals, super-oxides etc., on enzymes related with nucleic acid synthesis and genetic expressions.