Role Of ‘Serial Dilution’ And ‘Succussion’ In The Process Of Molecular Imprinting Involved In Potentization

We have learned that homeopathic potentization involves ‘serial dilution’ and ‘succussion’ or violent shaking.
Nobody so far scientifically explain what is the exact role of ‘succussion’ or ‘violent shaking’ in deciding the final outcome during homeopathic potentization, or why simple progressive dilution is not enough in homeopathic drug preparation.
We cannot potentize a drug by doing serial dilution only, avoiding the process of succussion. You cannot also potentize a drug by succussion only, avoiding serial dilution. We all know dilution and succussion are essential steps in perfect method of potentization. But we need a scientifically viable explanation.
I am trying to answer this question from the MIT view that potentization is a process of ‘molecular imprinting’. For molecular imprinting to happen, drug molecules have to be allowed to form ‘hydration complexes’ or ‘host-guest complexes’ by interacting with the water-alcohol molecules used as imprinting medium. This is done by mixing drug substances with the vehicle and allowing to form a uniform solution.
For preparing molecular imprints, we have to remove the drug molecules lying entrapped in the medium as ‘guest-host complexes’, and make the hydration shells empty. Succussion or violent shaking plays its role at this stage.
Our scientific study regarding the role of ‘succussion’ or violent shaking of drug solutions in the process potentization should begin with a deep study of hydrodynamics of the phenomenon known as cavitation.
Cavitation is the formation of bubble-like gaps in a liquid. Mechanical forces, such as the moving blades of a ship’s propeller or sudden negative changes in pressure, can cause cavitation. Violent shaking of fluids may cause cavitation. Skimming or separating butter from milk by violent agitation is an example of practical utilization of cavitation.
Put it in a different way, cavitation is the formation of vapor cavities in a liquid – i.e. small liquid-free zones (“bubbles” or “voids”) – that are the consequence of cavitational forces acting upon the cavitational liquid. It usually occurs when a liquid is subjected to rapid changes of pressure that cause the formation of cavities where the pressure is relatively low. When subjected to higher pressure, the voids implode and can generate an intense shock wave.
Cavitation happening in solutions of very low dilutions due to violent shaking done during homeopathic potentization will result in formation of nanobubbles. Due to hydrodynamic forces, drug molecules entrapped in the hydration shells of of water-alcohol medium will be adsorbed into the microfilms of nanobubbles. When the shaking is stopped and solution put to rest, these nanobubbles, along with the drug molecules adsorbed into it, will rise to the top layer of the solution. It will result in the removal of drug molecules from ‘host-guest’ complexes, leaving the free hydration shells as ‘molecular imprints’ in the lower layers of the solution.
By this process, drug molecules begin to concentrate in top layers, and the number of drug molecules gradually decreases in the lower layers of the solution. The upper layer that contains the remaining drug molecules are transferred to next bottle for making next higher potencies, and will be utilized for molecular imprinting the next bottle. As the serial dilution goes higher to approach Avogadro limit, lower layers will become completely free of drug molecules, and the drug molecules collected in top layers get transferred to the next bottle. The lower portions, devoid of any drug molecules, will be saturated with ‘molecular imprints’ only.
Phenomena of ‘cavitation’ and ‘nanobubble formation’ due to succussion plays a decisive role in the production of molecular imprints during homeopathic potentization, by removing the drug molecules from the hydrogen-bonded supra-molecular ‘vehicle-drug’ or ‘guest-host’ complexes formed in the solution. As such, ‘succussion’ is an inevitable part of effective ‘molecular imprinting’.
According to my view, this is the exact mechanism by which molecular imprints are prepared by ‘serial dilution’ and ‘succussion’ involved in the process of homeopathic potentization.
This view is corroborated by the IIT-B studies which says they could detect molecules of original drug substances floating in the ‘top layers’ of highly diluted drugs, which could be explained only by the phenomenon of ‘cavitation’, ‘nanobubble formation’ and rising of drug molecules to top layers due to succussion. Same time, their conclusion that these ‘nanoparticles’ seen on the ‘top layers’ are the active principles of potentized drugs is untenable, since it is not the ‘top layers’ only, but the ‘whole’ dilution up to the last drop is found to be therapeutically effective. Such a therapeutic activity of ‘whole’ dilution, even without any chance of drug molecule remaining in it could be explained only by ‘molecular imprinting’ as proposed by MIT.

Author: Chandran Nambiar K C

I started practicing homeopathy in 1970, when I was 20 years old and studying for final year of BSc (Zoology) course. My interest in homeopathy happened very accidentally, through a constant relationship with a local practitioner who happened to be father of my classmate. I was a regular visitor in his clinic, where from I started reading BOERICKE MATERIA MEDICA and other homeopathic books, which helped me to cure myself my troublesome asthma that have been haunting me since my childhood days. I became a voracious reader of homeopathy. I was also deeply involved in studying marxism and dialectical materialism during my college days, which attracted me to political activities. MARXISM and HOMEOPATHY became two essential parts of my intellectual and practical life, which still continues so. Even though I joined DHMS course in a karnataka homeopathic college, I could not continue it due to my intense involvement in revolutionary political activities that resulted in jail life and a lot of criminal cases. Once that phase was over, I took a diploma in veterinary science and became a livestock inspector in animal husbandry department under govt of kerala. I have been continuing my study and practice of homeopathy all through these years. Since CCH act came into force only in 1976, and it contained provisions allowing existing practitioners to continue, my homeopathic practice went smoothly in parallel with my government job. In 1987, co-operating with some local homeopaths and social activists, I started Kannur District Homeopathic Hospital Sociey, which established a chain of hospitals and homeopathic clinics in different parts of Kannur district. After a few years I had to leave the society for some political reasons, and I established a 100 bedded well equipped homeopathic hospital in Taliparamba, employing a number of prominent homeopaths. That was ended up as a financial disaster for me due to many reasons, including my lack of skills as a money manager, and I was compelled to close down my dream project with in a short period. I lost huge money I invested, lost my reputation, and it pulled me into a debt trap. I learned a lot of valuabl lessons from this failure- about life, human psychology, relationships, and above all, about myself. I realized failure is the greatest teacher, if you are prepared learn from it. I learned how will power and determination to win will help us come back into life as a phoenix from our own ashes. I learned, one does not fail unless he stops fighting and accepts failure. My failure and the hardships that followed has moulded my personality in such a way that I can now withstand any disaster and fight back. I tell you, you will not know what life really is, unless you miserably fail at least once in your life. By this time, I left my government job also, and settled as a full time homeopathic practitioner. By this practice, I could repair my earlier financial losses, and establish well in life. It was during this period that I felt the need of developing a simple and user-friendly homeopathic software, that resulted in the evolution of SIMILIMUM, which was later upgraded into SIMILIMUM ULTRA. Similimum Ultra was well accepted by the profession, and it collected good revenues which continues even today. I stopped my practice a few years back , and concentrated in the study and research activities to evolve scientifically viable explanations to the so-called riddles of homeopathy. This unrelenting study resulted in MIT or Molecular Imprints Therapeutics, which provides a scientific and rational explanation for homeopathy. I started a homeopathic discussion group on facebook called HOMEOPATHY FOR TOTAL CURE, which has more than 35000 homeopaths as members. By this work on facebook, I could establish close relationship with many homeopaths around the world. It goes on. I could successfully convert facebook as my office and work place, from where I propagate my MIT ideas, co-ordinate my works for homeopathic community, and sell my Similimum Ultra Software. My years of hardwork in search of HOW HOMEOPATHY WORKS ultimately resulted in the publication of a book titled REDEFINING HOMEOPATHY (3000 pages, 3 volumes, hard bound, Rs 6000), in which I have compiled my articles regarding my scientific explanations of basic principles of homeopathy. These ideas are called MIT or MOLECULAR IMPRINTS THERAPEUTICS. MIT is now included in the syllabus of MD (HOM) course of prestigious DY PATIL DEEMED UNIVERSITY, PUNE, INDIA. Research department of SARADA KRISHNA HOMEOPATHIC COLLEGE, Kulashekharam, Tamilnadu, India, the only NAC accredited homeopathy college in India, has recently taken up certain reserch projects for proving the scientific explanations proposed by MIT. Based on MIT perspective of homeopathy, I had developed an MIT PROTOCOL for scientific homeopathy, and initiated a project for establishing a chain of MIT NETWORK CLINICS all over India, where MIT PROTOCOL will be practiced. More over, I have developed a whole range of 351 MIT FORMULATIONS, which are disease-specific combinations of post-avogadro diluted homeopathy drugs. NOW I AM IN 71st YEAR OF MY LIFE, AND STILL LOOKING FOR NEW HORRIZONS!

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