Sarcodes Should Be Understood In Terms Of The Biological Ligands They Contain

Elsewhere im my articles I have discussed about need of developing a new range of Molecular Imprinted Drugs using biological ligands  as the templates for imprinting.

Sarcodes used in homeopathy should be understood in terms of biological ligands they contain. When potentizing the sarcodes, we are actually producing Molecular Imprints of their constituent biological ligands.

First of all we have to understand why the molecular imprints of biological ligands are so much important as therapeutic agents.

All normal biological interactions being part of all biological processes actually happen by binding of a biological molecule with its natural ligands. Biological molecules such as cellular and intercellular  receptors, Various enzymes, transport molecules etc have bind with different natural ligand molecules to do their work.

These natural ligands have to bind to specific binding sites or active sites of the biological molecules in order to initiate a biochemical interaction between them. Various endogenous or exogenous alien molecules having conformational similarity with natural ligands can compete with natural ligands and produce a molecular inhibition, which amounts to a state of pathology. Since the competing pathogenic molecules and natural ligands have some conformational similarities, molecular imprints of natural ligands can obviously act as artificial binding pockets for those pathogenic molecules also. That is how the molecular imprints of natural ligands or sarcodes work as powerful therapeutic agents.

Two important questions have to be answered regarding sarcodes when considering from MIT perspective:

1. If sarcodes are natural biological ligands having specific functional roles in human organism, how they become pathogenic agents, requiring the intervention of their own potentized forms or ‘molecular imprints’?

2. If the sarcodes are biological ligands being essential parts of living system, will not their physiological functions get negatively affected by the use of their potentized forms, since it is true that potentized form of a drug substance can antidote the biological effects of same drug in crude form?

Let us consider pituitary hormones first. They play a decisive role in the whole metabolism of the organism, and hence called ‘master gland’. Pitutary hormones control many enzyme systems in our body. Then how can they act as pathogenic agents, requiring the use of potentized pituitary extract?

Next question is, when we use potentized pitutrin as a sarcode, will it not act as an antidote towards molecular forms of pituitary hormones and create dangerous
consequences, by disrupting the whole endocrine activities mediated by pituitary hormones?

Pepsinum is very important in digestion of proteins. If pepsinum 30 is given to a person, will it create problems in protein digestion by deactivating pepsin molecules? If they cannot antidote pepsin molecules, how can they act as therapeutic agents?

Thyroid hormones play very important roles in metabolic activities in the living organism. Then how it can be pathogenic agents, requiring the intervention of potentized thyroidinum? Will not potentized thyroidinum hinder the biological processes mediated by thyroid hormones?

These are very pertinent questions we have to answer while trying to explain the science behind using of potentized sarcodes.

We can answer these questions only if we know the dynamics of molecular processes involved in biochemical interactions.

Every biological molecules, especially those belonging to hormones, signaling molecules(cytokines), neuro-chemicals, antibodies and enzymes being circulated in the organism enter into two types of biological interactions:

1. ‘On-target interactions’ 2. ‘Off-target interactions’.

‘On-target’ interactions are those happening between natural ligands and their genuine natural biological targets. Such interactions are essential part of vital processes through which biochemical pathways are carried unhindered.

Natural ligands and their genuine targets interact through two steps:

a). molecular identification and binding, which is effected by complementary conformational affinity between targets and ligands,

b). actual chemical interaction, which is effected by perfect charge affinity between ligands and their natural targets.

Off-target interactions are those accidentally happening between ligands and wrong targets having conformational affinity only. In the absence of exact charge affinity, no chemical changes occur. Such interactions are always ‘inhibitory’, temporarily or permanently deactivating the involved biological molecules. Such ‘inhibitory’ off-target
interactions inevitably lead to derangement in associated biochemical pathways resulting in pathological states.

‘Off-target’ inhibitions caused by biological molecules such as hormones, enzymes, antibodies, signaling molecules(cytokines) and neurochemicals are causative
factors of a wide range of pathological conditions in living beings.

Sarcodes, or potentized preparations of these biological molecules, which contain their ‘molecular imprints’, can effectively remove these molecular inhibitions and thereby act as therapeutic agents. Here lies the importance of sarcodes in homeopathic

Then comes the issue of selective action of the potentized sarcodes. As any other molecular imprints, molecular imprints in potentized sarcodes also cannot interfere in in the interactions between natural ligands and their genuine targets which involves conformational affinity as well as charge affinity. Since molecular imprints act through conformational affinity only, they can interfere in only inhibitory ‘off-target’ interactions.

It is now obvious that thyroidinum 30 cannot interfere in the essential biochemical processes mediated by thyroid hormones, Piturin 30 cannot interfere in the natural actions of pituitary hormones. This principle is applicable to all potentized sarcodes. We can use potentizeds arcodes above 12c without any fear of adverse effects.

Sarcodes or potentized biological ligands can play a very important role in the treatment of diverse types of diseases belonging to metabolic, emotional, psychosomatic, and ontological factors. They can also be part of constitutional prescriptions.

Pathogenic molecules cause diseases by binding to the biological targets and inhibiting their actions by mimicking as their natural ligands, due to the similarity of conformations of their functional groups.

Molecular Imprints of biological ligands can bind and deactivate the pathogenic molecules having functional groups similar to that of the biological ligands used for preparing the particular Molecular Imprints .

It is by this molecular mechanism that the molecular imprints of thyroid hormones contained in potentized THYROIDINUM removes the molecular inhibitions in the cellular receptors of thyroid hormones caused by pathogenic molecules.

We often experience cases where the patient shows symptoms of thyroid deficiency, but thyroid function tests will show normal production of thyroid hormones. It is a very confusing situation for physicians. What actually happens is, cellular receptors of thyroid hormones are blocked by some pathogenic molecules having functional groups similar to those of thyroid hormones binding to the receptors, presenting the interactions between thyroid hormones and their receptors.

If potentized applied in such cases, molecular imprints contained in the potentized drugs will bind to the pathogenic molecules, there by clearing the pathological inhibitions of receptors. Interactions between thyroid hormones and their biological targets are brought back to normal, and the deficiency symptoms of thyroid hormones are relieved.

It is by this same biological mechanism most of the HORMONE REMEDIES as well as the whole class of SARCODES used in homeopathy actually work. We should study SARCODES in terms of biological ligands they contain.



Author: Chandran Nambiar K C

I started practicing homeopathy in 1970, when I was 20 years old and studying for final year of BSc (Zoology) course. My interest in homeopathy happened very accidentally, through a constant relationship with a local practitioner who happened to be father of my classmate. I was a regular visitor in his clinic, where from I started reading BOERICKE MATERIA MEDICA and other homeopathic books, which helped me to cure myself my troublesome asthma that have been haunting me since my childhood days. I became a voracious reader of homeopathy. I was also deeply involved in studying marxism and dialectical materialism during my college days, which attracted me to political activities. MARXISM and HOMEOPATHY became two essential parts of my intellectual and practical life, which still continues so. Even though I joined DHMS course in a karnataka homeopathic college, I could not continue it due to my intense involvement in revolutionary political activities that resulted in jail life and a lot of criminal cases. Once that phase was over, I took a diploma in veterinary science and became a livestock inspector in animal husbandry department under govt of kerala. I have been continuing my study and practice of homeopathy all through these years. Since CCH act came into force only in 1976, and it contained provisions allowing existing practitioners to continue, my homeopathic practice went smoothly in parallel with my government job. In 1987, co-operating with some local homeopaths and social activists, I started Kannur District Homeopathic Hospital Sociey, which established a chain of hospitals and homeopathic clinics in different parts of Kannur district. After a few years I had to leave the society for some political reasons, and I established a 100 bedded well equipped homeopathic hospital in Taliparamba, employing a number of prominent homeopaths. That was ended up as a financial disaster for me due to many reasons, including my lack of skills as a money manager, and I was compelled to close down my dream project with in a short period. I lost huge money I invested, lost my reputation, and it pulled me into a debt trap. I learned a lot of valuabl lessons from this failure- about life, human psychology, relationships, and above all, about myself. I realized failure is the greatest teacher, if you are prepared learn from it. I learned how will power and determination to win will help us come back into life as a phoenix from our own ashes. I learned, one does not fail unless he stops fighting and accepts failure. My failure and the hardships that followed has moulded my personality in such a way that I can now withstand any disaster and fight back. I tell you, you will not know what life really is, unless you miserably fail at least once in your life. By this time, I left my government job also, and settled as a full time homeopathic practitioner. By this practice, I could repair my earlier financial losses, and establish well in life. It was during this period that I felt the need of developing a simple and user-friendly homeopathic software, that resulted in the evolution of SIMILIMUM, which was later upgraded into SIMILIMUM ULTRA. Similimum Ultra was well accepted by the profession, and it collected good revenues which continues even today. I stopped my practice a few years back , and concentrated in the study and research activities to evolve scientifically viable explanations to the so-called riddles of homeopathy. This unrelenting study resulted in MIT or Molecular Imprints Therapeutics, which provides a scientific and rational explanation for homeopathy. I started a homeopathic discussion group on facebook called HOMEOPATHY FOR TOTAL CURE, which has more than 35000 homeopaths as members. By this work on facebook, I could establish close relationship with many homeopaths around the world. It goes on. I could successfully convert facebook as my office and work place, from where I propagate my MIT ideas, co-ordinate my works for homeopathic community, and sell my Similimum Ultra Software. My years of hardwork in search of HOW HOMEOPATHY WORKS ultimately resulted in the publication of a book titled REDEFINING HOMEOPATHY (3000 pages, 3 volumes, hard bound, Rs 6000), in which I have compiled my articles regarding my scientific explanations of basic principles of homeopathy. These ideas are called MIT or MOLECULAR IMPRINTS THERAPEUTICS. MIT is now included in the syllabus of MD (HOM) course of prestigious DY PATIL DEEMED UNIVERSITY, PUNE, INDIA. Research department of SARADA KRISHNA HOMEOPATHIC COLLEGE, Kulashekharam, Tamilnadu, India, the only NAC accredited homeopathy college in India, has recently taken up certain reserch projects for proving the scientific explanations proposed by MIT. Based on MIT perspective of homeopathy, I had developed an MIT PROTOCOL for scientific homeopathy, and initiated a project for establishing a chain of MIT NETWORK CLINICS all over India, where MIT PROTOCOL will be practiced. More over, I have developed a whole range of 351 MIT FORMULATIONS, which are disease-specific combinations of post-avogadro diluted homeopathy drugs. NOW I AM IN 71st YEAR OF MY LIFE, AND STILL LOOKING FOR NEW HORRIZONS!

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