We should study aphorisms of organon in the light of advanced knowledge provided by modern science.
What Dr Samuel Hahnemann taught us regarding “similarity of symptoms” two centuries ago should be understood in modern advanced scientific knowledge environment as “similarity of chemical molecules” that “compete” each other for binding to “similar” biological targets, that lead to “similar” molecular inhibitions or similar “displacements” and “similar” deviations in biochemical pathways, that are naturally expressed through “similar symptoms”.
Once you understand the real meaning and relevance of above explanation provided by MIT, you can realise how much scientific is “Similia Similibus Curentur” and HOMEOPATHY!
ORGANON- APHORISM 20:
“This Spirit like Power to alter mans state of health which lie hidden in the inner of medicines can in itself never be discovered by us by a mere effort of reason , it is only by experience of the phenomena it displays when acting on the state of health of man that we can become clearly Cognizant of it._”
According to MIT view, it is not any “spirit like power”. The capacity of a medicinal substance to produce biological effects in living bodies lies in the structure and conformations of individual chemical molecules contained in it, by which they bind to various molecular targets inside the body and produce biomolecular inhibitions and cascading deviations in associated biochemical pathways, which are expressed through diverse trains of mental and physical symptoms.
ORGANON – APHORISM 21:
“How as it is deniable that the curative principle in medicines is not in itself perceptible , and as in pure experiments with medicines conducted by the mOst accurate observers, nothing can be observed that can constitute them medicines or remedies except that power of causing distinct alterations in the state of health of the human body, and particularly in that of healthy individual, and of exciting in him various definite morbid symptoms so it follows that when medicines act as remedies , they can only bring their curative property into play by means of this their power of altering mans state of health by the production of peculiar Symptoms and that therefore , We have only to rely on the Morbid phenomena which the medicines produces in the healthy body as the sole possible revelation of their in-dwelling curative power in order to learn what disease-producing power, and at the same time what disease-curing power, each individual medicines possess”.
As per MIT VIEW based on modern scientific knowledge, therapeutic properties of a substance is determined by the chemical and conformations of individual constituent molecules contained in that particular substance. When applied on healthy individuals for drug proving, these chemical molecules bind to various biological molecules and produce molecular inhibitions in related biochemical pathways, which are expressed through diverse groups of mental and physical symptoms. When drug symptoms and disease symptoms are similar, it means the drug substance as well as disease substance contain similar chemical molecules with similar functional groups, by which they can compete each other to bind to similar molecular targets. It is this competitive relationship with disease substance that produce a therapeutic effect when drug substance is used as a medicinal agent in a disease condition. This is the biological mechanism of cure involved in similia Simmilibus Curentur
©Chandran Nambiar KCRedefining homeopathy
ORGANON- APHORISM 22:
“But as nothing is to be observed in disease that must be removed in order to change them into health besides the totaity of their signs and Symptoms, and likewise medicines can show nothing curative besides their tendency to produce morbid symptoms in healthy persons and to remove them in diseased persons , it follows, on the one hand, that medicines only become remedies and capable of annihilating disease, because the medicinal substances, by exciting certain artificial mOrbid state, removes and abrogates the symptoms alredy present, to wit the natural mOrbid state we Wish to Cure. On the Other hand, it follows that for the totality of the Symptoms of the disease to be cured, that Medicine must be sought which (according as experience shall prove whether the mOrbid Symptoms are mOst readily , certainly and permenently removed and changed into helath by similar or opposite medicinal symptoms ) proved to have the greatest tendency to produce similar or opposite symptoms.”
This aphorism contains FOUR important statements.
Statement 1 in aphorism 22:
“Nothing is to be observed in disease that must be removed in order to change them into health besides the totality of their signs and symptoms”.
In modern scientific perspective, hahnemann’s phrase “totality of signs and symptoms” includes not only the “physical and mental symptoms” that we learn from our drug provings and read in our materia medica books, but a wider whole of SUBJECTIVE and OBJECTIVE symptoms expressed by the patient. All the laboratory reports regarding pathophysiological biochemical changes in the patient, all the radiological and endoscopic investigations, and every information collected by the physician with the help of advanced technological extensions of his sense organs belong to the class of OBJECTIVE symptoms. As such, what Hahnemann said in the statement quoted above is scientifically true and relevant even today.
Statement 2 in aphorism 22:
“Medicines can show nothing curative besides their tendecy to produce morbid symptoms in healthy persions and to remove them in diseased persons.”
Actually, “morbid symptoms in healthy persions” produced by a drug substance represent the biomolecular inhibitions produced in various biochemical pathways by the individual chemical molecules contained in the particular drug substance. Since disease-causing and disease-curing properties of drug substance is determined by the chemical properties of those constituent molecules. If the symptoms produced by a drug substance is SIMILAR to the symptoms expressed in a particular disease condition, it means the drug molecules and disease-causing molecules have a COMPETITIVE relationship, which could be ustilzed for its therapeutic application as per the homeopathic law of SIMILIA SIMILIBUS CURENTUR.
Statement 3 in aphorism 22:
“Medicines become remedies and capable of annihilating disease, only because the medicinal substances, by exciting certain artificial morbid state, removes and abrogates the symptoms already present, to wit the natural morbid state we wish to cure.”
“Medicines become remedies and capable of annihilating disease” only because the chemical molecules contained in it can compete with the disease-causing molecules having SIMILAR functional groups in binding to SIMILAR biological target molecules, which could be identified by comparing the drug symptoms and the symptoms of “natural morbid state we wish to cure.”
Statement 4 in aphorism 22:
“For the totality of the symptoms of the disease to be cured, that medicine must be sought which is proved to have the greatest tendency to produce similar or opposite symptoms.”
For the totality of the symptoms of the disease to be cured, that medicine must be sought which is proved to have the greatest tendency to produce symptoms SIMILAR to the symptoms of disease we are dealing with, which means our drug substance contains some chemical molecules that are having a COMPETITIVE relationship with the disease-causing molecules in binding to similar biomolecular targets.