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“ശാസ്ത്രീയമായ ഗവേഷണ പഠനങ്ങൾവഴി നവീകരിക്കപ്പെട്ട ആധുനിക ഹോമിയോ ചികിത്സാരീതിയുടെ ഗുണഫലങ്ങൾ ജനങ്ങളെ പരിചയപ്പെടുത്തുന്നതിനായി ഹാനിമാൻ ജന്മവാർഷികത്തോടനുബന്ധിച്ച് Center for Research in Redefining Homeopathy (CRRH) “ശാസ്ത്രീയഹോമിയോപ്പതി അനുഭവിച്ചറിയുക” എന്ന 6 മാസം നീണ്ടുനിൽക്കുന്ന ഒരു സൗജന്യ ചികിത്സാ പദ്ധതി ആവിഷ്കരിച്ചിരിക്കുകയാണ്. ശ്രീകണ്ഠപുരം എം എം കോംപ്ലക്സിൽ പ്രവർത്തിക്കുന്ന MIT SCIENTIFIC HOMEOPATHY CHAMBER എന്ന സ്ഥാപനം വഴിയാണ് ഈ പദ്ധതി നടപ്പിലാക്കുന്നത്. പഴകിയതോ താൽക്കാലികമോ ആയ എല്ലാവിധ ശാരീരിക-മാനസിക രോഗങ്ങൾക്കും, ജീവിതശൈലീരോഗങ്ങൾക്കും, ലൈംഗിക-വന്ധ്യതാ പ്രശ്നങ്ങൾക്കും, മദ്യ-മയക്കുമരുന്ന്-ലഹരി അടിമത്തത്തിനും പ്രത്യേകം തയാർചെയ്യപ്പെട്ട ഹോമിയോ ഔഷധങ്ങൾ ഉപയോഗിച്ച് വിദഗ്ധ ഡോക്ടർമാർ MIT PROTOCOL അനുസരിച്ചുള്ള ശാസ്ത്രീയ ഹോമിയോപ്പതി ചികിത്സ നൽകുന്നതാണ്. ഈ പദ്ധതി അനുസരിച്ച് കൺസൾട്ടേഷനും ഔഷധങ്ങളും പൂർണമായും സൗജന്യമായിരിക്കും. താൽപര്യമുള്ളവർ ഈ നോട്ടീസോ വാട്ട്സപ്പ് വഴി ലഭിച്ച ഈ മെസേജോ സഹിതം ശ്രീകണ്oപുരം എം എം കോപ്ലക്സിലുള്ള ഞങ്ങളുടെ സ്ഥാപനത്തിന്റെ കൗണ്ടറിൽ വന്ന് പേരും വ്യക്തിവിവരങ്ങളും നൽകിയാൽ സൌജന്യ ചികിത്സക്കായി രജിസ്റ്റർചെയ്ത് കാർഡ് വാങ്ങിക്കാവുന്നതാണ്. നേരിട്ടു വരാതെതന്നെ 9747320252 എന്ന ഫോൺ നമ്പറിൽ വിളിച്ച് പേർ രജിസ്റ്റർ ചെയ്യാവുന്നതുമാണ്.”

When you say NANOPARTICLES of elemental atoms contained in original drug substances are the ACTIVE PRINCIPLES of homeopathic potentized drugs, first of all you are bound to explain where from this unending supply of original substances come in even in minutest doses of preparations diluted much above avogadro limit or 12c, whereas it is well known to everybody that number of molecules in a sample of substance will be limited by avogadro number.

Remember, what the scientists of IIT-B said was only that they could “detect nanoparticles of elemental particles floating randomly in the 1% top layer of the solution”!

You are bound to explain how these “random particles” found to be floating on “top 1% layer” of solution could be the active principles of each and every drops and split drops of even the “bottom most layer” of drugs used by homeopaths!

Will you theorize using your “quantum science” that unlimited number of elemental particles are generated by the process of serial dilution and shaking involved in potentization?

When you say NANOPARTICLES of elemental atoms contained in original drug substances are the ACTIVE PRINCIPLES of homeopathic potentized drugs, you are bound to explain by what mechanism the complex chemical molecules contained in drug substances are converted into nanoparticles or “clusters of elemental atoms” by the simple process of serial dilution involved in the process of homeopathic potentization.

Do you think the strong co-valent bonds that hold atoms together in complex chemical molecules could be broken and atoms liberated by the simple mechanical energy applied during shaking or succussion? If so, can anybody be so ridiculous to imagine to split the simple water molecules into hydrogen and oxygen by shaking water taken in a bottle?

When you say NANOPARTICLES of elemental atoms you claim to have detected in some highly diluted samples subjected to spectroscopic studies are the ACTIVE PRINCIPLES of homeopathic potentized drugs, you are bound to explain how these simple elemental particles or their clusters can represent or reproduce the biological and medicinal properties of highly complex biological molecules such as proteins, enzymes, alkaloids, glycosides, cytokines, hormones, biological ligands, metabolites etc etc contained in the drug substances used to prepare potentized homeopathic drugs.

For example, the highly neurotoxic alkaloid STRYCHNINE contained in nux vomica is a chemical molecule with formula C21H22N2O2. BRUCINE is another alkaloid with chemical formula C23H26N2O4, and with different set of chemical and biological properties . Both of them contain only carbon, hydrogen, nitrogen and oxygen, but in different numbers. Do you think these individual elemental atoms generated by division of strychnine can produce the neurotoxic biological effects of strychnine?

Do you think the individual hydrogen and oxygen atoms produced by division of water molecule can produce the chemical or biological properties of water?

Please understand, it is not merely the individual constituent elemental atoms that produce the biological properties of a chemical molecule, but their peculiar organization, spacial placement of atoms, energy levels, molecular conformation and a lot of other factors are involved in it.

It is utter foolishness to think that individual elemental particles or their clusters isolated from complex chemical molecules can represent or produce their highly complex biological or medicinal effects.

Please be careful not to forget these simple basic things while theorizing that nanoparticles of elemental atoms are the active principles of potentized homeopathic drugs.

We should study aphorisms of organon in the light of advanced knowledge provided by modern science.

What Dr Samuel Hahnemann taught us regarding “similarity of symptoms” two centuries ago should be understood in modern advanced scientific knowledge environment as “similarity of chemical molecules” that “compete” each other for binding to “similar” biological targets, that lead to “similar” molecular inhibitions or similar “displacements” and “similar” deviations in biochemical pathways, that are naturally expressed through “similar symptoms”.

Once you understand the real meaning and relevance of above explanation provided by MIT, you can realise how much scientific is “Similia Similibus Curentur” and HOMEOPATHY!

ORGANON- APHORISM 20:

“This Spirit like Power to alter mans state of health which lie hidden in the inner of medicines can in itself never be discovered by us by a mere effort of reason , it is only by experience of the phenomena it displays when acting on the state of health of man that we can become clearly Cognizant of it._”

MY COMMENT:

According to MIT view, it is not any “spirit like power”. The capacity of a medicinal substance to produce biological effects in living bodies lies in the structure and conformations of individual chemical molecules contained in it, by which they bind to various molecular targets inside the body and produce biomolecular inhibitions and cascading deviations in associated biochemical pathways, which are expressed through diverse trains of mental and physical symptoms.

ORGANON – APHORISM 21:

“How as it is deniable that the curative principle in medicines is not in itself perceptible , and as in pure experiments with medicines conducted by the mOst accurate observers, nothing can be observed that can constitute them medicines or remedies except that power of causing distinct alterations in the state of health of the human body, and particularly in that of healthy individual, and of exciting in him various definite morbid symptoms so it follows that when medicines act as remedies , they can only bring their curative property into play by means of this their power of altering mans state of health by the production of peculiar Symptoms and that therefore , We have only to rely on the Morbid phenomena which the medicines produces in the healthy body as the sole possible revelation of their in-dwelling curative power in order to learn what disease-producing power, and at the same time what disease-curing power, each individual medicines possess”.

MY COMMENT:

As per MIT VIEW based on modern scientific knowledge, therapeutic properties of a substance is determined by the chemical and conformations of individual constituent molecules contained in that particular substance. When applied on healthy individuals for drug proving, these chemical molecules bind to various biological molecules and produce molecular inhibitions in related biochemical pathways, which are expressed through diverse groups of mental and physical symptoms. When drug symptoms and disease symptoms are similar, it means the drug substance as well as disease substance contain similar chemical molecules with similar functional groups, by which they can compete each other to bind to similar molecular targets. It is this competitive relationship with disease substance that produce a therapeutic effect when drug substance is used as a medicinal agent in a disease condition. This is the biological mechanism of cure involved in similia Simmilibus Curentur
©Chandran Nambiar KCRedefining homeopathy

ORGANON- APHORISM 22:

“But as nothing is to be observed in disease that must be removed in order to change them into health besides the totaity of their signs and Symptoms, and likewise medicines can show nothing curative besides their tendency to produce morbid symptoms in healthy persons and to remove them in diseased persons , it follows, on the one hand, that medicines only become remedies and capable of annihilating disease, because the medicinal substances, by exciting certain artificial mOrbid state, removes and abrogates the symptoms alredy present, to wit the natural mOrbid state we Wish to Cure. On the Other hand, it follows that for the totality of the Symptoms of the disease to be cured, that Medicine must be sought  which (according as experience shall prove whether the mOrbid Symptoms are mOst readily , certainly and permenently removed and changed into helath by similar or opposite medicinal symptoms ) proved to have the greatest tendency to produce similar or opposite symptoms.”

This aphorism contains FOUR important statements.

Statement 1 in aphorism 22:

“Nothing is to be observed in disease that must be removed in order to change them into health besides the totality of their signs and symptoms”.

MY COMMMENTS:

In modern scientific perspective, hahnemann’s phrase  “totality of signs and symptoms” includes not only the “physical and mental symptoms” that we learn from our drug provings and read in our materia medica books, but a wider  whole of SUBJECTIVE and OBJECTIVE symptoms expressed by the patient. All the laboratory reports regarding pathophysiological biochemical changes  in the patient, all the radiological and endoscopic investigations, and every information collected by the physician with the help of advanced technological extensions of his sense organs belong to the class of OBJECTIVE symptoms. As such, what Hahnemann said in the statement quoted above is scientifically true and relevant even today.

Statement 2 in aphorism 22:

“Medicines can show nothing curative besides their tendecy to produce morbid symptoms in healthy persions and to remove them in diseased persons.”

MY COMMMENTS:

Actually, “morbid symptoms in healthy persions” produced by a drug substance represent the biomolecular inhibitions produced in various biochemical pathways by the individual chemical molecules contained in the particular drug substance. Since disease-causing and disease-curing properties of drug substance is determined by the chemical properties of those constituent molecules. If the symptoms produced by a drug substance is SIMILAR to the symptoms expressed in a particular disease condition, it means the drug molecules and disease-causing molecules have a COMPETITIVE relationship, which could be ustilzed for its therapeutic application as per the homeopathic law of SIMILIA SIMILIBUS CURENTUR.

Statement 3 in aphorism 22:

“Medicines become remedies and capable of annihilating disease, only because the medicinal substances, by exciting certain artificial morbid state, removes and abrogates the symptoms already present, to wit the natural morbid state we wish to cure.”

MY COMMMENTS:

“Medicines become remedies and capable of annihilating disease” only because the chemical molecules contained in it can compete with the disease-causing molecules having SIMILAR functional groups in binding to SIMILAR biological target molecules, which could be identified by comparing the drug symptoms and the symptoms of “natural morbid state we wish to cure.”

Statement 4 in aphorism 22:

“For the totality of the symptoms of the disease to be cured, that medicine must be sought  which is proved to have the greatest tendency to produce similar or opposite symptoms.”

MY COMMMENTS:

For the totality of the symptoms of the disease to be cured, that medicine must be sought  which is proved to have the greatest tendency to produce symptoms SIMILAR to the symptoms of disease we are dealing with, which means our drug substance contains some chemical molecules that are having a COMPETITIVE relationship with the disease-causing molecules in binding to similar biomolecular targets.

When I talk about “combinations of post-avogadro diluted drugs”, some “classical” friends come with the quesion whether these combinations are “proved”? One of them declared: “If the the symptoms of combination drugs are same as single drug in provings, then only we can accept this theory.. Without clinical proving of combination drugs how we can accept this theory sir.”

First of all, I am not bothered whether anybody “accepts” my suggestions or not. No compulsions at all. I have already explained my rationale regarding “combinations of post-avogadro diluted drugs”. If you are capable of understanding my rationale, and convinced about the the scientific wisdom underlying it, you can accept.

Asking for “proving” of “combinations of post-avogadro diluted drugs” by itself shows that they have not seen or understood my explanations regarding drug proving.

A drug substance could be “proved” only if it can act upon biological molecules and inhibit their normal interactions. Only then it can produce a state of “drug pathology” as well as “drug symptoms”. Inorder to act upon biological molecules and change their actions, drug substance should contain some “chemical” molecules. Most of the drug substances contain diverse types of chemical molecules having their own individual chemical properties. During drug proving, a drug substance interact with our biological molecules not as a singular entity, but the individual drug molecules contained in the drug substance act upon various biological targets by their individual chemical properties, and produce molecular inhibitions that are expressed through diverse groups of symptoms that we compile in our materia medica.

Dear friends, please understand, durg substances potentized above avogadro limit or 12c will not contain even a single drug molecule, if they were genuinely potentized.

Your idea of “proving” post avogadro diluted drugs actually originated from this lack of scientific understanding regarding how drug substances act upon the body and produce symptoms. If you are talking about some mysterious “dynamic energy” that works upon a spiritual “vital force”, sorry sir, I am not interested in discussing that nonsense again and again. I have already done it more than enough earlier.

According to my view, potentization involves a process of MOLECULAR IMPRINTING. Spacial conformations of drug molecules are imprinted as three dimensional nanocavities in the water-alcohol supramolecular matrices. Each individual chemical molecule contained in the drug substance undergoes molecular imprinting as an individual unit. As such, drugs potentized above 12c or avogadro limit will contain diverse types of molecular imprints representing the diverse types of chemical molecules contained in the original drug substance. These individual molecular Imprints are the ACTIVE PRINCIPLES of post avogadro diluted drugs we use in homeopathy. Molecular Imprints act as ARTIFICIAL BINDING POCKETS for pathogenic molecules by their conformtional affinities, deactivate them, and remove the Molecular inhibitions they have produced in the biological molecules. This is the biological mechanism of Homeopathic cure. Molecular imprints cannot interfere in the normal interactions between biological molecules and their natural ligands, and hence, cannot produce any molecular errors in normal vital processes. That is why I say post avogadro diluted drugs cannot produce any pathological conditions or produce any drug symptom. Obviously, idea of conducting drug proving using drugs potentized above post avogadro limit is simply RIDICULOUS!

When we combine post avogadro diluted drugs, we are actually adding more MOLECULAR IMPRINTS together. Since Molecular Imprints cannot interact each other, there is no harm in combining any number of potentized drugs. Individual Molecular Imprints will remain as such, and act only upon specific pathogenic molecules having conformational affinity when introduced into the body as therapeutic agents.

My scientific explanations of Homeopathy may not agree with your “classical” beliefs that evolved in the 200 year old primitive knowledge environment. Sorry for that. Either you update yourselves, or reject my ideas and remain eternally blind! It is your choice!

Arsenic Album or Arsenic Trioxide is a chemical substance that can inhibit more than 200 essential enzymes in our body involved in diverse types of biomolecular processes related with genetic transcription, metabolism, energy conversions etc etc. This is due to the ability of Arsenic ions to bind to the cysteine radicals which are part of active sites all enzymes. Almost every biochemical pathways in the living body are deranged by the action of arsenic. This is the reason why the homeopathic materia medica of arsenic album is so rich with symptoms associated with almost all organs and systems of the body.

Arsenic content may be high in people due to living in certain areas, consuming arsenic rich ground water, cigarette smoking, eating unpolished rice, prawns and crabs, exposure to arsenic containing environments, etc etc. Arsenic may enter the body through contaminated liquors, Chinese, Ayurvedic, unani or Herbal preparations, industrial exposures, chemically treated wooden furniture etc also. Arsenic content will naturally be high in aged people, as it has a tendency to accumulated in the body over years through exposures.

It is an already established fact that during viral infections, persons having high levels of arsenic in their body are prone to develop serious complications such as respiratory failure, acute myocardial degeneration, renal failures, liver failures, multiple organ failures etc faster than those having low arsenic levels.

Researchers working upon arsenic toxicity problems in certain arsenic affected countries have already proved that ARSENIC ALBUM 30 can antidote and reverse the chronic effects of arsenic toxicity, and remove the symptoms.

My suggestion to the experts involved in current pandemic research is that determination of arsenic levels in the body of covid patients should be made mandatory, so that high risk people could be identified and better care provided.

Arsenic Album 30 contains MOLECULAR IMPRINTS of arsenic trioxide molecules. Molecular imprints are three dimensional nanocavities formed in water-alcohol supra-molecular matrix through a host-guest interactions between templates and diluent medium during the process of homeopathic POTENTIZATION. Molecular imprints of arsenic trioxide contained in Arsenicum Album 30 can act as artificial binding pockets for arsenic ions and deactivate them, thereby removing the molecular inhibitions they have produced in the enzyme systems of the body.

By using Arsenicum Album 30 in sufficient quantities and frequencies to provide molecular imprints in optimum levels, it will be possible to prevent dangerous complications and multiple organ failures in patients affected with current pandemic, so as to prevent the chances of morbidities due to the disease. Complications and mortality rates could be definitely lowered by use of Arsenic Alb 30.

I don’t know how to get this very important message reach the right persons in right time, or how to convince the scientific basis of this approach described above.

A word to homeopaths : It is a nonsense idea that Arsenic album 30 will “boost immunity”. Arsenic Alb 30 will not contain any chemical molecules that can act as antigens to initiate production of antibodies and boost immune system. But it will surely prevent complications even if you get infected, if molecular imprints of arsenic is available in the body during the time of virus infection.

Homeopaths currently involved in distribution of Arsenicum Album 30 should realize the hard truth that the dosage you are giving now is actually of no use. 4 or 5 medicated sugar pills for 3-4 days you give now cannot provide the sufficient quantity of molecular imprints required to produce desired biological effects. To ensure optimum availability of molecular imprints, medicine should be used in drop doses at least twice a day until the epidemic threat is over. Please understand, it is not any mysterious “dynamic energy” or “vibrations” that work in our potentized drugs. It is “material” MOLECULAR IMPRINTS, that act as “artificial binding pockets” for pathogenic molecules, and deactivate them. As such, dosage and repetition should be appropriate to ensure this availability. I would suggest minimum 1 or 2 drops direct on tongue bds until epidemic is over.

There is a wild propaganda going on, claiming that homeopathy medicine ASPIDOSPERMA is the GENUS EPIDEMICUS of current pandemic, and people are desperately running from store to store to get a bottle of this “miracle drug” to save their dear ones gasping for oxygen. They also recommend the use of Vanadium as an “oxygen supplier”.

It is claimed that a few drops of “mother tincture” of aspidosperma given twice or thrice for a few days will relieve the breathlessness, and will be helpful in curing the disease.

Problem underlying this claim as well as the propaganda is that homeopaths fail to understand  the difference between MOLECULAR forms and MOLECULAR IMPRINTS forms of drugs.

They also fail to remember the primary lesson that if a drug is found to  be GENUS EPIDEMIC for a disease, it will be administered only in potencies above 12c, and it is NEVER used in mother tincture form.

Crude drugs, mother Tinctures, Potencies below 12c and biochemic TRITURATIONS are MOLECULAR forms of drugs, since they contain molecules of drug substances.

Potencies above 12c or Post-avogadro dilutions do not contain drug molecules, but MOLECULAR IMPRINTS only.

We must not forget the fact that drug symptoms provided in our materia medica actually constitute the list of symptoms that are generated in healthy persons by the use of these drugs in crude form.  Indiscriminate long-term use of mother tinctures containing plant enzymes, poisonous alkaloids, glycosides and various other phyto-chemical ingredients is an  unpardonable  crime even if it is done in the name of homeopathy. The chemical molecules contained in these tinctures might give temporary relief  by nutritional supplementation, or by competitive relationship towards pathological  molecules due to their  conformational similarity. But it is evident from their symptomatologies  that those chemical molecules are capable of creating dangerous pathological molecular inhibitions in various bio-chemic channels in the organism.

We should never forget that the subjective and objective symptoms provided in our materia medica were createdby the molecular errors happened in healthy individuals during drug proving.

Regarding ASPIDOSPERMA, even though homeopaths enthusiastically quote “It stimulates the respiratory centers and increases the oxygen in the blood” from Boericke materia Medica, they conveniently ignore the following statement in Clarke’s materia Medica: “Hale says ASPIDOSPERMA produces in animals respiratory paralysis, slowed heart, and paralysis of extremities.”

Even though it is said in materia Medica that VANADIUM is an “oxygen carrier”, please understand, it is only a chemical property of Vanadium in its molecular form. Vanadium potentized above 12c will not contain any single molecule of Vanadium, and hence, it is totally irrational to expect Vanadium in potentized form to act as an “oxygen supplier”. The widely quoted statement from materia Medica “it increases amount of hemoglobin, also combines its oxygen with toxines and destroys their virulence” is actually applicable to molecular forms of Vanadium only. Vanadium 30 will not contain even a single molecule of Vanadium, and hence, this property cannot be attributed to vanadium 30.

Same time, vanadium in Molecular form is highly toxic, and it is not at all safe to use Vanadium in 3x or potencies below 12c. It is now well known that molecular forms of VANADIUM is a competitive inhibitor of various enzymes such as ATPases, alkaline and acid phosphatases, and protein-phosphotyrosine phosphatases, and hence, very dangerous if given in Molecular form.

Molecular forms of drugs act by the chemical properties of constituent molecules, whereas MOLECULAR IMPRINTS forms of drugs act by the conformational properties of Molecular imprints.

Since Molecular imprints cannot interfere in the normal interactions between biological molecules and their natural ligands, Molecular imprints forms of drugs cannot produce any short term or long term adverse effects.

On the other hand, Molecular forms of drugs can interact with biological molecules and produce inhibitions, and may cause harmful adverse effects. Even though mother Tinctures are considered Homeopathy drugs, they are no way different from allopathy drugs, when considered in terms of their active principles as well as biological mechanism of actions.

We know, many homeopathic practioners prescribe plenty of mother tinctures, low potency preparations and biochemic TRITURATIONS. They consider it genuine homeopathy, as they manufactured by homeopathy drug companies, and bear the label Homeopathic Medicines. They ignore the fact that mother Tinctures are never prescribed according to similia principles, or on the basis of totality of symptoms.

Mother tinctures and other Molecular forms of drugs may relieve some of the symptoms, due to their allopathic actions. But they are not only un-homeopathic in actions, but chances of emerging new pathological conditions due to them is a reality.

Homeopaths should understand, it is ideal to treat patients using potencies above  12c, which do not contain any trace of the drug molecules of the original drug. If our selection of drug is correct, there is no any chance of failure in such a protocol.

Actually, mother tinctures will have to be considered as identical to Ayurveda, Allopathy or Herbal treatment. Those homeopaths who indulge in excessive use of mother tinctures, without bothering  about their constituent drug  molecules and their adverse long term impacts on the organism, are more hazardous to human health than our allopathic counterparts. I humbly request them to think over.

For example, from our materia medica works, it may be understoodthat most of  those people who had participated in proving of  Hydrastis Canadensis developed symptoms of gastric ulcer and hyperacidity along with many other deep seated pathological conditions. Doctors who administer large doses of Hydrastis Tincture to relive gastric symptoms as part of homoeopathic treatment should note this point . Of course, we may get temporary relief, by the way of competitive relationships with pathological molecules, due to conformational similarity of drug molecules and pathogenic molecules. Prolonged use of Hydrastis Tincture not only produce the symptoms mentioned in the materia medica,  but may even induce very serious genetic errors to happen. If  hydrastis is the similimum for the patient, it will be effective in high potencies. This is real homeopathy.

Please do not be provoked when I say that those who give Vanadium 3x for supplying oxygen,  Passiflora for inducing sleep, Rauwolfia for lowering blood pressure and Syzijium for high blood sugar in their tincture form, are not practicing ideal Homeopathy even if they may be well known homeopaths.

No homeopath with some common sense, who had carefully read the material medica of Alfalfa will dare to prescribe it as tonics to improve the appetite and general health of innocent children. It is evident from its symptomatology that Alfalfais capable of producing diabetes, bulimia, and upsetting the normal functioning of kidneys.

We should remember that there was no exact knowledge regarding the long term evil effects of many drugs, when many of them were proved and their materia medica prepared. There was least knowledge about the genetic disorders they were likely to produce. It is found in Boecricke Materiamedica that Arsenic Bromide Mother Tincture is indicated for Diebetes. No physician with scientific awareness will even think of prescribing it today. Who will now dare to prescribe Ars iod 3x, Iodum 3x, Sulphur Q, or various compounds of Mercury and Lead only because they are found in our text books of Materia Medica?

We know a lot of homeopaths who make their patients consume for prolonged periods, the mother tinctures of several drugs, including various patented combinations flooding the market in the name of Homeopathy. How can Homeopaths prescribe them without any prick of conscience? Those who love homoeopathy should take urgent initiative to prevent such tendencies either through awareness programs and campaigns, or through stringent legislational procedures.

Since crude drugs and mother tinctures contain drug molecules that can act upon biological molecules, they can also bind to various biological targets in the organism. Obviously, there is always chance for creation of new molecular inhibitions and drug-induced pathologies when we use crude drugs and mother tinctures. That is the draw back of using mother tinctures even if they are similimum.

Advantage of drugs potentized above 12c, also known as post-avogadro Dilutions,   is that they do not contain any drug molecule, but only molecular imprints, which are only supra-molecular clusters of water and alcohol molecules. They can act upon pathogenic molecules only, not upon biological molecules. As such, potentized drugs cannot do any further harm to organism.

That is why MIT says use of mother Tinctures and other Molecular forms of drugs cannot be considered genuine Homeopathy. To be genuinely homeopathic regarding active principles as well as biological mechanism of action, we should use only post-avogadro diluted drugs.

Many homeopaths recently suggest VANADIUM 30 as a remedy for oxygen deficiency in blood during the current Covid 19 pandemic. This suggestion is based on the statements in some homeopathic materia Medica works regarding the “oxygen carrier” capacity of vanadium.

First of all, let us see what is said in Boericke Materia Medica about Vanadium:

“Its action is that of an oxygen carrier and a catalyzer, hence its use in wasting diseases.  Increases amount of hemoglobin, also combines its oxygen with toxines and destroys their virulence. Also increases and stimulates phagocytes. A remedy in degenerative conditions of the liver and arteries.

Anorexia and symptoms of gastro intestinal irritation; albumen, casts and blood in urine. Tremors; vertigo; hysteria and melancholia; neuro-retinitis and blindness. Anaemia, emaciation. Cough dry, irritating and paroxysmal, sometimes with haemorrhages. Irritation of nose, eyes and throat. Tuberculosis, chronic rheumatism, diabetes.

Acts as a tonic to digestive function and in early tuberculosis. Arterio-sclerosis, sensation as if heart was compressed, as if blood had no room in the aorta. Anxious pressure on whole chest. Fatty heart. Degenerative states, has brain softening.  Atheroma of arteries of brain and liver.

Dose:  6-12 potency. The best form is Vanadiate of Soda, 2 mg daily, by mouth.”

Clarke’s Dictionary of Materia Medica says about Vanadium as follows : 

“Addison’s disease. Atheroma. Fatty degeneration. Innutrition.
Burnett  tells how he came to use Vanadium through reading the result of some experiments on animals in which the Salts of Vanadium produced “true cell destruction, the pigment escaping, the liver being hit hardest.”  Burnett had at the time a case of “fatty liver, atheroma of the arteries, much pain corresponding to the course of the basilar artery, large, deeply pigmented patches on forehead, profound adynamia.” Vanadium restored the patient, who was seventy, and at eighty he was “hale and hearty.” Marc Jousset tells of experiments with salts of Vanadium, chiefly the meta-vanadate of sodium, by Lyonnet and others.  Animals poisoned by intravenous injections rapidly develop Cheyne-Stokes respiration; with little or no action on circulation or blood. These observers gave Vanadates to two hundred patients suffering from tuberculosis, chlorosis, chronic rheumatism, neurasthenia etc, and produced in nearly all cases increased appetite, strength, and weight. The amount of urea was also increased. They regard Vanadium as “an energetic excitant of nutrition,” and probably an oxydent stimulating organic combustion. The dose was 2-5 mgr. in twenty-four hours, and only on three separate days in the week.”

Obviously, Boericke and Clarke were saying about the use of “2-5 mg of Sodium Vanadate daily”. Not Vanadium 30! It makes a big difference.

Sodium vanadate is the inorganic compound  with the chemical formula  Na3VO4·2H2O (sodium orthovanadate dihydrate). It is a colorless, water-soluble solid.

Vanadates exhibit a variety of biological activities, in part because they serve as structural mimics of PHOSPHATES. By this mimicking, it acts as a COMPETITIVE INHIBITOR of ATPases, alkaline and acid phosphatases, and protein-phosphotyrosine phosphatases. By this competitive relationship VANADIUM acts as a SIMILIMUM for many disease conditions involving inhibitions of ATPases by various endogenous or exogenous pathogenic molecules having phosphate functional groups or moieties. 

ATPases  adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5′-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) etc are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion or the inverse reaction. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur. This process is widely used in all known forms of life

Transmembrane ATPases import many of the metabolites necessary for cell metabolism and export toxins, wastes, and solutes that can hinder cellular processes.

All the symptoms described by Boericke and Clarke are actually due to this inhibitory actions of vanadites  upon the various enzymes listed above, which lead to blocking of all biological pathways associated with involvement of PHOSPHATES. 

Please understand, Vanadium potentized above 12c used in homeopathy will not contain even a single molecule or atom of Vanadium. It contains only MOLECULAR IMPRINTS of vanadium, and hence, will act just opposite to the actions of Molecular or crude forms of Vanadium.  These Molecular imprints actually act by removing the molecular inhibitions caused in the various enzymes by Vanadium or any other pathogenic molecules having functional groups similar to vanadites or phosphates.

 Obviously, Vanadium 30 will not supply oxygen to the tissues as some homeopaths wrongly believe, but may be useful in deactivating harmful reactive oxygen species or ROS generated in the body during the disease processes. 

Even though Boericke and Clarke talks about use of “Vanadium Vanadate 2-5 mg daily” for therapeutic purposes, as per advanced scientific knowledge, vanadium is not a safe substance for human consumption.

Vanadium excess can be toxic and detrimental to human health like any other metal. For instance, occupational inhalation exposure to vanadium was found to induce acute respiratory symptoms, DNA damage in blood cells of workers from a vanadium pentoxide factory, and altered neurobehavioral functions. In turn, environmental overexposures to vanadium oxides attached to fine particulate matter were associated with increased risk of respiratory symptoms in children, and a higher risk of cardiovascular and respiratory hospitalizations of older people. ilRecently, urinary vanadium concentrations during pregnancy were positively associated with impaired fetal growth and preterm or early-term delivery. Association between the high level of trace elements including vanadium in the drinking water and the increased thyroid cancer incidence was suggested. A suicidal death after ingestion of an undetermined amount of ammonium vanadate has also been reported. In addition, laboratory-based studies conducted in animal models or cell cultures found that vanadium exposure can induce a variety of toxic effects such as cardiovascular effects, vascular endothelial dysfunction and arterial hypertension, immune toxicity, damage to the spleen and thymus, neurotoxicity, hippocampal alterations and memory loss, developmental disturbances, increased embryolethality and skeletal defects, and pulmonary toxicity. It should be added that, besides the dose of vanadium and the route of vanadium exposure, many other factors such as the form of vanadium (inorganic versus organic forms) and interactions with other elements such as selenium or magnesium can also influence vanadium toxicity.

Along with the studies of the toxic effects of vanadium, many investigators have been focused on the examination of potential medical applications of this mineral. These include antidiabetic or insulin-mimetic actions, antiviral effects, and anticarcinogenic activity. Among these effects, the antidiabetic action of vanadium complexes with organic ligands has been very intensively studied, which entered into stage II clinical trials. However, due to kidney problems in some patients, this study as an antidiabetic agent could not progress to the next phase of research. Indeed, the risks associated with vanadium intoxication such as vanadium-induced reactive oxygen species generation, adverse effects on the immune system, and a risk of mutagenesis are listed among the arguments against the antidiabetic application of vanadium. Reviews of the results of past and recent human studies on vanadium in diabetes have concluded that the use of vanadium compounds in oral diabetes therapy is misplaced.

Vanadium occurs as a natural component of the earth crust in various minerals, coal, and crude oil, and is released to the environment mainly due to human activities. The unique chemical and physical features of vanadium compounds make it an indispensable material in many industries. Its compounds are frequently used in the production of steel and titanium-aluminum alloys, as catalysts in the sulfuric acid manufacture, and in the production of pigments, inks, and varnishes. The latest use of vanadium involves green technologies and the production of vanadium-based redox flow batteries, which can store electricity produced from renewable sources such as wind or sun.  The industrial use of vanadium is on the increase and so is the release of vanadium to the environment.  Vanadium is one of the elements listed on the second drinking water contaminant candidate list that was announced by the United States Environmental Protection Agency in 2005. This is a list of contaminants that are known or anticipated to occur in public water systems and may require future regulations. Vanadium was reported to contribute to soil pollution.  Heavy oil combustion contributes to the release of vanadium as a component adhering to fine particulate matter observed in large urban and industrial agglomerations. High groundwater concentrations of vanadium of natural geological sources have been noted in volcanic areas.  Vanadium excess can be toxic and detrimental to human health like any other metal. For instance, occupational inhalation exposure to vanadium was found to induce acute respiratory symptoms, DNA damage in blood cells of workers from a vanadium pentoxide factory, and altered neurobehavioral functions. In turn, environmental overexposures to vanadium oxides attached to fine particulate matter were associated with increased risk of respiratory symptoms in children, and a higher risk of cardiovascular and respiratory hospitalizations of older people. Recently, urinary vanadium concentrations during pregnancy were positively associated with impaired fetal growth and preterm or early-term delivery. Association between the high level of trace elements including vanadium in the drinking water and the increased thyroid cancer incidence was suggested. A suicidal death after ingestion of an undetermined amount of ammonium vanadate has also been reported. In addition, laboratory-based studies conducted in animal models or cell cultures found that vanadium exposure can induce a variety of toxic effects such as cardiovascular effects, vascular endothelial dysfunction and arterial hypertension, immune toxicity, damage to the spleen and thymus, neurotoxicity, hippocampal alterations and memory loss, developmental disturbances, increased embryolethality and skeletal defects, and pulmonary toxicity. It should be added that, besides the dose of vanadium and the route of vanadium exposure, many other factors such as the form of vanadium (inorganic versus organic forms) and interactions with other elements such as selenium or magnesium can also influence vanadium toxicity.

Along with the studies of the toxic effects of vanadium, many investigators have been focused on the examination of potential medical applications of this mineral. These include antidiabetic or insulin-mimetic actions, antiviral effects, and anticarcinogenic activity. Among these effects, the antidiabetic action of vanadium complexes with organic ligands has been very intensively studied, which entered into stage II clinical trials. However, due to kidney problems in some patients, this study as an antidiabetic agent could not progress to the next phase of research. Indeed, the risks associated with vanadium intoxication such as vanadium-induced reactive oxygen species generation, adverse effects on the immune system, and a risk of mutagenesis are listed among the arguments against the antidiabetic application of vanadium. Reviews of the results of past and recent human studies on vanadium in diabetes have concluded that the use of vanadium compounds in oral diabetes therapy is misplaced. Vanadium compounds have attracted interest of researchers as potential antitumor agents. Vanadium as vanadyl sulfate has been used by weight training athletes as a nutritional supplement that can increase muscle mass. The role of vanadium in muscle development has been emphasized to be associated with its insulin-mimetic properties and anabolic effects. So far, however, human studies have failed to demonstrate significant effects of vanadium on the body composition and performance enhancement, and the use of vanadium as a sport nutrition supplement is not recommended. Vanadium is also a well-known constituent of the most commercialized titanium alloy named Ti-6Al-4V, which has been widely used in the manufacture of biomedical implants such as artificial hip joints, knee joints, and dental implants due to its excellent physical and mechanical properties. Again, however, the potential cytotoxicity of vanadium limits the medical value of the Ti-6Al-4V alloy. Recently, for example, a case of systemic allergic dermatitis to vanadium has been reported in a patient following placement of a titanium alloy plate in the left foot. Summing up, due to the intensive use of vanadium in industry and the vanadium environmental pollution often related with it as well as the popularity of vanadium-based dietary supplements and medicinal applications of vanadium compounds, increasing numbers of humans are likely to experience the exposure to vanadium compounds in the near future.

Vanadium enters the human body via the gastrointestinal tract or respiratory system. In the bloodstream, transferrin is the major serum protein of vanadium transport from blood into tissues.  Other serum proteins, i.e., albumin, hemoglobin, and immunoglobulin, and low-molecular ligands, e.g., lactate and citrate, can be involved in the blood transport of vanadium as well. From the blood, vanadium is transferred to different tissues such as the liver, kidney, heart, spleen, brain, and bones. Final excretion of absorbed vanadium occurs through urine. In the human body, vanadium can exist in oxidation state +5 (vanadate ions) or +4 (vanadyl cations). Cellular uptake of vanadium species proceeds via receptor-mediated endocytosis of vanadium-laden proteins (transferrin, albumin), phosphate or sulfate ion channels, or membrane citrate transporters. Reductants, e.g., glutathione, ascorbic acid, or NADH, convert pentavalent vanadium to a tetravalent state, the latter being regarded as a predominant oxidation state of vanadium within the cell. Simultaneously, oxidants such as NAD+, O2, and O22- can oxidize vanadyl back to vanadate.

Metabolic detoxification of vanadium possibly involves reduction of vanadate to vanadyl by cellular reductants, and  complexation reactions during which vanadyl interacts with cellular agents such as reduced glutathione (GSH), an oxidized form of glutathione (GSSG), L-cysteine, and cystine forming stable, nonharmful complexes. In addition, vanadium accumulates in bones by replacing bone phosphate in apatite Ca5(PO4)OH with vanadate. The storage of vanadium in bones is also recognized as a potent detoxification mechanism of vanadium in animals.

In contrast to the aforementioned chelating compounds, ascorbic acid was suggested to be a very effective and safe pharmacologic agent for the treatment of vanadium toxicity in humans. Detoxification of vanadium by ascorbic acid mainly relies on ascorbic acid-mediated reduction of vanadate to vanadyl and its high capacity to scavenge reactive oxygen species. Furthermore, vanadyl was found to interact with oxidation products of ascorbic acid forming stable complexes, which may allow excretion of vanadium from the organism. In addition, the results of studies have shown that pyruvic acid could be another potential antidote for the treatment of vanadium toxicity. The studies showed that this alpha-keto acid protected against vanadium-induced oxidative stress and cytotoxicity in a cell culture model. The mechanism of protection probably involves antioxidative effects of pyruvate, especially its ability to neutralize hydrogen peroxide, but still more research is required to elucidate this issue. 

It is well known that many edible plants are the main source of natural compounds acting as exogenous antioxidants. Exogenous antioxidants cannot be produced in the body and therefore must be provided through daily nutrition. They reinforce our intrinsic antioxidant system in the protection of the organism against reactive oxygen species-mediated injuries. As shown below in this review, research studies indicate that vanadium toxicity, which is strongly associated with prooxidant mechanisms, can be efficiently reduced or alleviated by dietary and plant-derived antioxidants. 

Very early studies already explored the efficiency of vitamin C (ascorbic acid, ascorbate) in the prevention and treatment of vanadm toxicity, and found that vitamin C was effective against acute vanadate and vanadyl intoxication. 

Some studies focused on the role of vitamin E (α-tocopherol) in the treatment of vanadium toxicity, which provided in vivo evidence that vitamin E acetate decreased sodium metavanadate-induced oxidative stress and histopathological changes in the testes of rats. Furthermore, vitamin E was demonstrated to exhibit protective activity against sodium metavanadate-mediated neurotoxicity in rat pups. In this study, vitamin E increased performance in neurobehavioral tests,  and decreased reactive astrogliosis in brain tissue of vanadium-treated animals. Both vitamins C and E exhibited protective activity against vanadium pentoxide-induced genotoxicity measured using a micronucleus assay in mouse polychromatic erythrocytes.

In addition, polyphenolic compounds (and other phytochemicals) may prove beneficial for the treatment of vanadium toxicity. 
In conclusion, although the investigations cited in this review show that supplementation with dietary antioxidants has beneficial effects on vanadium poisoning.

First of all, let us see what is said in Boericke Materia Medica about Vanadium:

“Its action is that of an oxygen carrier and a catalyzer, hence its use in wasting diseases. 

Increases amount of hemoglobin, also combines its oxygen with toxines and destroys their virulence. Also increases and stimulates phagocytes. A remedy in degenerative conditions of the liver and arteries.

Anorexia and symptoms of gastro intestinal irritation; albumen, casts and blood in urine. Tremors; vertigo; hysteria and melancholia; neuro-retinitis and blindness. Anaemia, emaciation. Cough dry, irritating and paroxysmal, sometimes with haemorrhages. Irritation of nose, eyes and throat. Tuberculosis, chronic rheumatism, diabetes.
Acts as a tonic to digestive function and in early tuberculosis. Arterio-sclerosis, sensation as if heart was compressed, as if blood had no room in the aorta. Anxious pressure on whole chest. Fatty heart. Degenerative states, has brain softening.  Atheroma of arteries of brain and liver.

Dose:  6-12 potency. The best form is Vanadiate of Soda, 2 mg daily, by mouth.”

Clarke’s Dictionary of Materia Medica says about Vanadium as follows : 

“Addison’s disease. Atheroma. Fatty degeneration.

Innutrition.Burnett  tells how he came to use Vanadium through reading the result of some experiments on animals in which the Salts of Vanadium produced “true cell destruction, the pigment escaping, the liver being hit hardest.”  Burnett had at the time a case of “fatty liver, atheroma of the arteries, much pain corresponding to the course of the basilar artery, large, deeply pigmented patches on forehead, profound adynamia.” Vanadium restored the patient, who was seventy, and at eighty he was “hale and hearty.” Marc Jousset tells of experiments with salts of Vanadium, chiefly the meta-vanadate of sodium, by Lyonnet and others.  Animals poisoned by intravenous injections rapidly develop Cheyne-Stokes respiration; with little or no action on circulation or blood. These observers gave Vanadates to two hundred patients suffering from tuberculosis, chlorosis, chronic rheumatism, neurasthenia etc, and produced in nearly all cases increased appetite, strength, and weight. The amount of urea was also increased. They regard Vanadium as “an energetic excitant of nutrition,” and probably an oxydent stimulating organic combustion. The dose was 2-5 mgr. in twenty-four hours, and only on three separate days in the week.”

Obviously, Boericke and Clarke were saying about the use of “2-5 mg of Sodium Vanadate daily”. Not Vanadium 30! It makes a big difference.

Sodium vanadate is the inorganic compound  with the chemical formula  Na₃VO₄·2H₂O (sodium orthovanadate dihydrate). It is a colorless, water-soluble solid.

Vanadates exhibit a variety of biological activities, in part because they serve as structural mimics of PHOSPHATES. By this mimicking, it acts as a COMPETITIVE INHIBITOR of ATPases, alkaline and acid phosphatases, and protein-phosphotyrosine phosphatases. 

All the disease conditions described by Boericke and Clarke are actually due to this inhibitory actions of vanadites upon the various enzymes listed above, which lead to blocking of all biological pathways associated with PHOSPHATES. 

Please understand, Vanadium potentized above 12c used in homeopathy will not contain even a single molecule or atom of Vanadium. It contains only MOLECULAR IMPRINTS of vanadium, and hence, will act just opposite to the actions of Molecular or crude forms of Vanadium.  These Molecular imprints actually act by removing the molecular inhibitions caused in the various enzymes by Vanadium or any other pathogenic molecules having functional groups similar to vanadites or phosphates. Obviously, Vanadium 30 will not supply oxygen to the tissues as some homeopaths wrongly believe, but may be useful in deactivating harmful reactive oxygen species or ROS generated in the body during the disease processes. 

Even though Boericke and Clarke talks about use of “Vanadium Vanadate 2-5 mg daily” for therapeutic purposes, as per advanced scientific knowledge, vanadium is not a safe substance for human consumption.

Vanadium excess can be toxic and detrimental to human health like any other metal. For instance, occupational inhalation exposure to vanadium was found to induce acute respiratory symptoms, DNA damage in blood cells of workers from a vanadium pentoxide factory, and altered neurobehavioral functions. In turn, environmental overexposures to vanadium oxides attached to fine particulate matter were associated with increased risk of respiratory symptoms in children, and a higher risk of cardiovascular and respiratory hospitalizations of older people. ilRecently, urinary vanadium concentrations during pregnancy were positively associated with impaired fetal growth and preterm or early-term delivery.

Association between the high level of trace elements including vanadium in the drinking water and the increased thyroid cancer incidence was suggested. A suicidal death after ingestion of an undetermined amount of ammonium vanadate has also been reported. In addition, laboratory-based studies conducted in animal models or cell cultures found that vanadium exposure can induce a variety of toxic effects such as cardiovascular effects, vascular endothelial dysfunction and arterial hypertension, immune toxicity, damage to the spleen and thymus, neurotoxicity, hippocampal alterations and memory loss, developmental disturbances, increased embryolethality and skeletal defects, and pulmonary toxicity. It should be added that, besides the dose of vanadium and the route of vanadium exposure, many other factors such as the form of vanadium (inorganic versus organic forms) and interactions with other elements such as selenium or magnesium can also influence vanadium toxicity.

Along with the studies of the toxic effects of vanadium, many investigators have been focused on the examination of potential medical applications of this mineral. These include antidiabetic or insulin-mimetic actions, antiviral effects, and anticarcinogenic activity. Among these effects, the antidiabetic action of vanadium complexes with organic ligands has been very intensively studied, which entered into stage II clinical trials. However, due to kidney problems in some patients, this study as an antidiabetic agent could not progress to the next phase of research. Indeed, the risks associated with vanadium intoxication such as vanadium-induced reactive oxygen species generation, adverse effects on the immune system, and a risk of mutagenesis are listed among the arguments against the antidiabetic application of vanadium. Reviews of the results of past and recent human studies on vanadium in diabetes have concluded that the use of vanadium compounds in oral diabetes therapy is misplaced.

A Complete Clinical Utility Software Package For Homoeopaths

As per the scientific explanation of homeopathy proposed by MIT or Molecular Imprints Therapeutics, potentized medicines contain MOLECULAR IMPRINTS or hydrogen bonded supra-molecular clusters of water/ethyl alcohol carrying the conformational imprints of drug molecules, which act artificial binding sites for pathogenic molecules and thereby removing the pathological molecular inhibitions.

One of the important predictions put forward to be verified for proving MIT was that supramolecular structure of potentized drugs will be different from that of unpotentized water-alcohol mixture, even though both contain same chemical molecules, which should be proved by tools and techniques of scientific methods.

I think the two remarkable works discussed below, one by Dr Tanmoy Maity, and the other by by Louis Rey, provide crucial support as very strong scientific proofs for this important prediction, thereby validating the MIT explanation of scientific homeopathy.

First study is one done by Tanmoy Maity (Department of Electrical Engineering, Indian School of Mines, Dhanbad, Jharkhand 826004, India), D. Ghosh & C.R. Mahata (Department of Electrical Engineering, Bengal Engineering and Science University, Shibpur, Howrah 711103, West Bengal, India), regarding effect of dielectric dispersion on potentised homeopathic medicines, which indicates a “rearrangement of vehicle molecules” in potentized drugs.

This report is available on
http://www.sciencedirect.com/science/article/pii/S1475491609001258

Second is one conducted by Louis Rey on thermo-luminescence of ultra-high dilutions of lithium chloride and sodium chloride, and published in December 2002, which is available in its full form at: http://www.janscholten.com/janscholten/Evidence_files/Rey.thermoluminescence.pdf E-mail address: ouis.rey@bluewin.ch (L. Rey).

STUDY I:

SCIENTIFIC EVIDENCE FOR RE-ARRANGEMENT OF VEHICLE MOLECULES DURING POTENTIATION :

This paper reports dielectric dispersion occurring in potentised homeopathic medicines subjected to variable frequency electric field using an instrumentation method developed by the authors. Oscillations occur in the direction of electric field, and are usually termed longitudinal/acoustic-mode vibrations.

The test material was lactose soaked with homeopathic medicine. Multiple resonance frequencies, forming a frequency-set, were observed repeatedly for each medicine.

The team reports experimental results for three potencies of Cuprum metallicum (Cuprum met) in the frequency range of 100 kHz–1 MHz. Each exhibits a set of resonance frequencies, which may be termed as its characteristic set. As the frequency-set of each medicine is different from those of others, each medicine may, therefore, be identified by its characteristic frequency-set. This suggests that potentised homeopathic medicines, which are chemically identical with the vehicle, differ from one another in the arrangement of vehicle molecules.

According to them, these “experiments show that potentised homeopathic medicines, which are chemically identical with the vehicle, differ from one another in the arrangement of vehicle molecules”.

“Difference in arrangement of vehicle molecules” strongly indicates the presence of “supra-molecular clusters of water and ethyl alcohol, into which the three-dimensional configuration of drug molecules are imprinted as nanocavities” as proposed by the hypothesis proposed by MIT.

The observation that “the resonance frequencies frequency-set of each medicine is different from those of others” strongly indicates clusters of water-ethyl alcohol molecules specifically rearranged in accordance with the shapes of constituent molecules of drug substance used for potentization.

Such a re-arrangement of vehicle molecules strongly indicates the process of ‘molecular imprinting’ happening during homeopathic potentization. Present work is a decisive step in the scientific understanding of homeopathy proposed by MIT.

STUDY II:

SCIENTIFIC EVIDENCE FOR SUPRAMOLECULAR STRUCTURAL CHANGES IN POTENTIZING MEDIUM HAPPENING BY THE PROCESS OF POTENTIZATION:

As per the reported work, ultra-high dilutions of lithium chloride and sodium chloride (10−30g cm−3) have been irradiated by X- and gamma rays at 77 K, then progressively re-warmed to room temperature. During that phase, their thermo-luminance has been studied and it was found that, despite their dilution beyond the Avogadro number, the emitted light was specific of the original salts dissolved initially.

This wonderful observation that high dilutions of salts very much above avogadro number retains the specific thermo-luminance patterns reminding of of original salts seems to be very crucial. This phenomenon could be well explained only in terms of supramolecular nanostructures of water carrying the imprints of exact ‘conformations’ of ‘individual’ molecules of salts, as explained by MIT concepts.

Thermo-luminance studies have been developed and utilized so far as a “tool to study the structure of solids, mainly ordered crystals”. In the present study, the researchers successfully utilized it in ultra-high aqueous dilutions, which demonstrates the short range ‘crystalline’ character of water as well as high dilution preparations.

Actually, the researchers took up this work to ‘challenge’ the ‘water memory’ theory, but proved it otherwise. They confess in their report: “we thought that it would be of interest to challenge the theory according which preexistent ‘structures’ in the original liquid, developed around some added chemicals, could survive a great number of successive dilutions when done under vigorous mechanical stirring”.

Another important point to be noted is that the researchers did not use ‘commercial samples’ as most ‘researches’ do, but prepared themselves 15c dilutions of lithium chloride and sodium chloride under the guidance of boiron labs. This fact provides more scientific credence to this study.

The study “showed quite clearly that the initial addition of a solute (NaCl and LiCl) in the original D2O leaves a permanent effect even when, by successive dilutions made under strong vibration, all traces of solute have disappeared.” The results were reproduced in several repeated experiments, “beyond any ambiguity”.

Thermally stimulated luminance—often called thermo-luminance—is a well known phenomenon amongst the thermally stimulated processes (thermally stimulated conductivity—thermally stimulated electron emission—thermogravimetry—differential thermal analysis and differential scanning calorimetry, etc.). Its theory and applications have been fully developed inter alia by McKeever, Chen and Visocekas and it proved to be a most interesting tool to study the structure of solids, mainly ordered crystals. To that end, the studied material is “activated” at low-temperature, usually by radiant energy (UV, X-rays, gamma rays, electron beams, or neutrons) which most generally creates electrons–holes pairs which become separately “trapped” at different energy levels. Then, when the irradiated material is warmed up, the heating serves as a trigger to release the initially accumulated energy and the trapped electrons and holes move and recombine. A characteristic glow is emitted most often under the shape of different successive peaks according to the depths of the initial traps. As a general rule this phenomenon is observed in ordered crystals though it can be equally seen in disordered materials such as glasses. In that mechanism, imperfections in the lattice play a major role and are considered to be the place where luminance centres appear. Thus, thermoluminance is a good tool to study these imperfections and understand how they appear in the crystal.

This is exactly along those lines that the researchers carried our first investigations, starting, this time, from liquids which were turned into stable solids by low-temperature cooling.

Working essentially with water—mainly deuterium oxide—they have shown that the thermoluminance glow of irradiated hexagonal ice consisted in two major peak areas—Peak 1 near 120 K and Peak 2 near 166 K having well-defined emission spectra the D2O samples giving a much higher signal than the H2O ones.

In both cases, un-irradiated samples gave no signals whatsoever. For both D2O and H2O it was shown that the relative intensity of the thermoluminance glow was a function of the irradiation dose and, that at least for Peak 2, it did show a maximum between 1 and 10 kGy .

As a first hypothesis on the nature of the emission itself it has been suggested by Teixeira that Peak 2 could be connected to the hydrogen-bond network within the ice which, in turn, could result from the structure of the original liquid sample, whilst Peak 1 looked to be closely related to the molecule. This strengthens the views on the involvement of hydrogen bonds in this mechanism.

To develop this concept further, the researchers did select to study the effect of lithium chloride on the thermoluminescence of irradiated D2O ice since this particular substance is known to suppress hydrogen bonds. The result, indeed, is spectacular and, at the relatively low concentration of 0:1M, Peak 2 is totally erased whereas the basic emission of Peak 1 remains almost unchanged.

At that point the researchers thought that it would be of interest to challenge the theory according which pre-existent “structures” in the original liquid, developed around some added chemicals, could survive a great number of successive dilutions when done under vigorous mechanical stirring.

To that end they prepared, courtesy of the BOIRON LABORATORIES, ultra-high dilutions of lithium chloride and sodium chloride by successive dilutions to the hundredths, all done under vigorous mechanical stirring (initially 1 g in 100 cm3, then 1 cm3 of this solution in 99 cm3 of pure D2O … and so on) until they reached— theoretically—at the 15th dilution, a “concentration” of10−30 g cm−3. A reference sample of D2O alone was also prepared according to this technique, still keeping vigorous agitation (150 strokes=7:5 s at each successive “dilution” step).

They did proceed, then, to the “activation” of these materials by irradiation according the following experimental protocol.

One cubic centimeter of each solution is placed in aluminium test cavities of 20 mm diameter and 2 mm depth and frozen to −20◦C on a cold metallic block. The frozen systems are kept 24 h at −20◦C to achieve stability into their crystallization patternand they are immersed into liquid nitrogen and kept at −196◦C for 24 h.

In a first set of experiments the frozen ice disks are irradiated at 77 K with 100 kV X-rays to achieve a dose of 0:4 kGy (30 min). Previous determinations were done to check that the disks having identical positions in the field did receive the same dose (dosimetry has been done using Harwell, FWT, and alanine dosimeters).

After irradiation, all the “activated” samples are transferred into a liquid nitrogen container and kept, there, for a week-time, to even out whatever small differences could exist between them.

Finally, all samples are placed in the thermoluminance equipment and their respective glow recorded—with both a photo-multiplier and a CCD camera connected to a spectrograph—in the course of rewarming (3=min) between 77 and 13 K, as has been done in our previous published experiments.

Much to their surprise, the experimental results do show—without any ambiguity— that for an X-ray dose of 0:4 kGy the thermoluminescence glows of the three systems were substantially different. These findings did prove to be reproducible in the course of many different identical experiments.

To compare the curves between them the researchers normalized the emitted light readings taking Peak 1 as the reference. In doing so, we obtain for Peak 2 the different curves presented which show quite clearly that the initial addition of a solute (NaCl and LiCl) in the original D2O leaves a permanent effect even when, by successive dilutions made under strong vibration, all traces of solute have disappeared. More remarkable were the fact that, by far, lithium chloride demonstrates a stronger hydrogen bond suppressing “ghost” effect which could be related to the larger size of the lithium ion.

A second set of experiments done with gamma rays (courtesy of CELESTIN Reactor, COGEMA, Marcoule), at a higher dose (19 kGy) did confirm these findings

It appears, therefore, that the structural state of a solution made in D2O can be modified by the addition of selected solutes like LiCl and NaCl. This modification remains even when the initial molecules have disappeared and the effect is the same at different irradiation doses (0.4 –19 kGy) and for different radiant sources (X-rays, gamma rays). As a working hypothesis, the researchers propose that this phenomenon results from a marked structural change in the hydrogen bond network initiated at the onset by the presence of the dissolved ions and maintained in the course of the dilution process, probably thanks to the successive vigorous mechanical stirrings.

Researchers had no any idea of Molecular Imprinting. They proposes the following hypothesis for explaining their observation:

“As a working hypothesis, we propose that this phenomenon results from a marked structural change in the hydrogen bond network initiated at the onset by the presence of the dissolved ions and maintained in the course of the dilution process, probably thanks to the successive vigorous mechanical stirrings.”

See, this hypothesis comes very close to the concept of Molecular Imprinting!

If we fail to explain the observations of this monumental research in terms of Molecular Imprinting, there remains the danger that it will be hijacked by ‘energy medicine’ theoreticians, by interpreting in terms of ‘essence of drugs’, ‘information’, ‘vibrations’ and the like. Actually, Jan Scholten has already done such an exercise, by saying ‘information’ of drugs imprinted in water are the cause of thermoluminance observed by the researchers. Then he very cleverly fits this thermoluminance into his energy medicine frame work of ‘bioluminance’, vibrations, vital force, resonance and other pseudoscientific theories.

To be specific, precise and fitting to modern scientific knowledge system and its accepted paradigms, it is better to say ‘molecular imprints’ of original drug molecules are the cause of similarity of thermoluminance the researchers could observe. Such an explanation will clearly demonstrate that we are talking about the ‘complementary’ shape of drug molecules imprinted into nanostructures of water, which produce therapeutic effects by acting as ‘artificial binding sites’ for pathogenic molecules.

While introducing the concept of MIASMS, Hahnemann was actually trying to explain the role of residual effects of acute INFECTIOUS DISEASES in precipitating chronic disease conditions. His main focus was on infectious ITCH/LEPROSY, SYPHILIS and HPV-GONORRHOEA complex, which were most widespread around his place during his time.

Hahnemann, from his practical experience of applying ‘Similia Similibus Curentur’, came to the conclusion that complete cure is not possible using SIMILIMUM only, if such a similimum is selected using totality of currently existing symptoms only, without considering the MIASMS or residual effects of previous acute infectious diseases.

Even though Hahnemann could rightly observe the role of MIASMS or residual effects of infectious diseases in the causation as well as the curative process of chronic diseases, he could not explain the exact biological mechanism by which this phenomenon works. This failure was due to the primitive state scientific knowledge available during his period, which later led to various kinds unscientific and “dynamic” interpretations by his “disciples” and “followers” which continue till the present day.

Using the scientific knowledge already available now, I have been trying to explore the exact molecular mechanism by which residual effects of acute INFECTIOUS diseases contribute to the development of chronic disease conditions, which Hahnemann called MIASMS.

It is common knowledge that ANTIBODIES are generated in our body against infectious agents or proteins that are alien to our genetic codes. Even after infectious disease is over, these antibodies remain in our body for long periods, even for whole life in certain cases.

Since ANTIBODIES are native globulin PROTEINS that have undergone misfolding by interacting with alien proteins or infectious agents, they can themselves behave as aliens in the organism and produce pathological inhibitions by binding to various OFF-TARGET biological molecules. Such molecular inhibitions caused by ANTIBODIES are the real molecular level villains playing behind various chronic diseases such as AUTOIMMUNE DISEASES, PROTEINOPATHIES, AMYLOID DISEASES AND PRION DISEASES.

Hahnemann called these chronic residual effects of ANTIBODIES as MIASMS.

See, how Hahnemann’s concept of CHRONIC DISEASES relating it with INFECTIOUS MIASMS, paves the way for a SCIENTIFIC understanding of a whole class of grave diseases, and developing of a whole new range of therapeutic agents and techniques to combat them.

Hahnemann’s observations of CHRONIC DISEASES, relating it with INFECTIOUS DISEASES, would have been a revolutionary event in medical history, had anybody- be it hahnemann himself, his followers or scientists- taken up the task of explaining it in scientific terms.

Had anybody asked the question how an infectious disease can cause life-long RESIDUAL EFFECTS in the organism even after the infection is over, everything would have been clear. It would have been obvious that infectious agents can produce life-long RESIDUAL EFFECTS in the form of CHRONIC DISEASES only through ANTIBODIES generated in the body against infectious agents.

Such a realization would have helped medical as well as scientific community to view ANTIBODIES from a different perspective- as CAUSATIVE AGENTS of diverse types of CHRONIC DISEASES- over and above their role as DEFENSE molecules.

It was hahnemann, who for the first time proposed that diverse types of CHRONIC DISEASES could be produced in the long run by INFECTIOUS agents, which he called MIASMS.

I have been trying to explain in scientific terms, how CHRONIC DISEASES could be produced by infectious agents, even after the infections are over. This led me into the realization that INFECTIOUS AGENTS can produce life-long chronic disease dispositions only through OFF-TARGET actions of ANTIBODIES generated in the body against them.

By Chandran Nambiar KC
Redefining Homeopathy
Whatsapp 9446520252

Without acquiring a baseline knowledge of CHEMISTRY OF LIFE, you cannot follow the MIT explanation regarding biological mechanism of homeopathic cure.

By the term ‘living organism’, we indicate a highly organized complex material system with a specific quantity, quality, structure and functions of its own, which is capable of self-controlled growth and reproduction of its progeny, through an interaction involving constant exchange of matter and energy with its environment.

The phenomenon we call ‘life’ exists through a continuous chain of highly complex biochemical interactions which control each other known as METABOLIC PATHWAYS, which depend up on each other and are determined by each other.

A ‘living organism’ represents a much higher and advanced level of organized existence of the same elements of matter we meet in the inorganic world, different only in its structural organization and functional complexity. The universal phenomenon of material motion we find as part of primary existence of matter itself, attains the wonderful qualities of life, due to this complex structural organization.

In fact, phenomenon of ‘life’ was the result of a continuous evolutionary process of primary matter in this universe through millions of years, attaining different levels of organizational and functional forms. Primary forces, sub-atomic particles, elementary atoms, simple chemical molecules, complex inorganic molecules, carbon containing organic molecules, bio-molecules, complex bio-polymers, RNA-DNA-Protein structures, organelles, unicellular organisms, multi-cellular organisms, diverse species of plants and animals, and ultimately Homo Sapiens- these are the prominent milestones in the known evolutionary ladder on earth, panning through millions and millions of years. Human beings represent the highest form of this material evolutionary history on earth, as far as it is known to us.

Parallel to this biological evolution, we can perceive a systematic evolution and perfection of the nervous system also. Simple forms of conditioned reflexes that existed in primitive organisms, gradually evolved into nerve cells, neural networks and ultimately into a well organized nervous system in higher animals. In higher forms of life such as humans, this nervous system has attained such a structural and functional perfection that human brain and its diverse faculties have begun playing a decisive role even in the existence and development of that species and even life on earth itself. Of course, collective labor, language and social relations also played a major role in this evolutionary process.

A living organism can exist only through a continuous interaction and material exchange with its environment. There is an unceasing flow of matter and energy in both directions, between internal and external environments of the organism. Metabolism, or ‘life process’ is the term used to describe the sum total of this bidirectional flow. The moment this bi-directional flow of matter and energy ceases, the organism can no longer exist.

A living organism is distinguished from other non-living forms of matter by certain fundamental features such as: high level of structural organization, the ability to convert and utilize energy, continuous material exchange with environment, self regulation of chemical transformations, and, reproduction or transfer of hereditary information. A state of disease may ensue when any of the biochemical pathways governing these fundamental factors of life are disturbed. Obviously, it is impossible to make a scientific study of pathology and therapeutics without an understanding of these subjects.

Complex bio-molecules which participate in the diverse chemical processes of life are broadly classified into four major groups: Proteins, Carbohydrates, Lipids and Nucleic Acids. These are polymers of simple chemical components or sub units, called monomers. The monomers of proteins are amino acids, and those of carbohydrates are monosaccharides. Lipids are polymers of fatty acids. The monomers of Nucleic acids are known as nulcleotides. These bio-molecules are considered to be the building blocks of life on earth, and are never seen in the non-living world. These bio-molecules, with their highly complex structure and organization, interact each other in the organism through hundreds of bio-chemic pathways, collectively called ‘vital processes’.

Scientific explanation of Homeopathy should be based on a proper understanding of the the complex dynamics of bio-molecular interactions involved in vital processes, especially protein biochemistry.

Understanding PROTEIN CHEMISTRY and PROTEIN DYNAMICS is an essential part of understanding LIFE, DISEASE and CURE:

Proteins are a class of highly complex nitrogen-containing bio-molecules, functioning as the primary carriers of all the biochemical processes underlying the phenomenon of life. There exist millions of protein molecules belonging to thousands of protein types in a living organism.

Each protein molecule is formed by the polymerization of monomers called amino acids, in different proportions and sequences. Each protein type has its own specific role in the biochemical interactions in an organism. Most of the amino acids necessary for the synthesis of proteins are themselves synthesized from their molecular precursors inside the body. A few types of amino acids cannot be synthesized inside the body, and have to be made available through food. These are called essential aminoacids.

There are specific protein molecules assigned for each biochemical process that take place in the body. Various proteins play different types of roles, such as biological catalysts or enzymes, receptors, transport molecules, hormones, antibodies etc. Some proteins function as specialized molecular switches, systematically switching on and off of specific biochemical pathways.

Proteins are synthesized from amino acids, in conformity with the neucleotide sequences of concerned genes, with the help of enzymes, which are themselves proteins.

‘Protein synthesis’ and ‘genetic expression’ are very important part of vital process. It may be said that genes are molecular moulds for synthesizing proteins of specific conformations. There are specific genes, bearing appropriate molecular codes of information necessary for synthesizing each type of protein molecule. Even the synthesis of these genes happens with the help of various enzymes, which are protein molecules. There is no any single bio-molecular process in the living organism, which does not require an active participation of a protein molecule of any kind.

The most important factor we have to understand while discussing proteins is the role of their three-dimensional spacial organization evolving from peculiar disulphide bonds and hydrogen bonds. Water plays a vital role in maintaining the three dimensional organization of proteins intact, thereby keeping them efficient to participate in the diverse biochemical processes.

Proteins exhibits different levels of molecular organization: primary, secondary, tertiary and quaternary. It is this peculiar three dimensional structure that decides the specific biochemical role of a given protein molecule. More over, co-enzymes and co-factors such as metal ions and vitamins play an important role in keeping up this three-dimensional structure of protein molecules intact, thereby activating them for their specific functions. Buffering properties of body fluids also are decisive in maintaining the specific conformations of proteins and keeping them reactive.

Whenever any kind of error occurs in the particular three-dimensional structure of a given protein molecule, it obviously fails to interact with other biomolecules to accomplish the specific functions it is intended to play in the concerned biochemical processes. Such a failure leads to further harmful deviations in several biochemical processes in the organism, that require the participation of this particular protein, ultimately resulting in a cascading of multitude of molecular errors. This is the fundamental molecular mechanism of pathology, which we perceive as disease of some or other category.

These deviations in biochemical pathways are expressed as various groups of subjective and objective symptoms of disease. The organic system exhibits a certain degree of ability and flexibility to overcome or self repair such molecular deviations and preserve the state of homeostasis required to maintain life. Anyhow, if these deviations happen in any of the vitally decisive biochemical pathways, or, if these are irreversible, the bio-chemical processes ultimately stop and death happens.

Disease is a state of derangement in biochemical interactions so as to disrupt the normal pathways of vital processes of the organism

Derangement in normal biochemical interactions amounting to a state of disease may happen due to diverse reasons.

1. GENETIC FACTORS: Defects in genetic codes arising from heredity or acquired by mutations result in the absence of certain proteins (enzymes, receptors, antibodies etc) that are essential for normal biochemical interactions.defective genes may also synthesis faulty proteins with wrong conformation, which can act as endogenous pathogenic agents by binding to various biological targets.

2. EPIGENETIC FACTORS: Defects of enzymes involved in genetic expressions and post synthetic translations and modifications of protein molecules act as epigenetic factors of diseases.

3. NUTRITIONAL FACTORS: Nutritional deficiencies of essential building blocks and precursors of biological molecules, such as amino acids and other monomers, vitamins, co-factors, elements, metal ions, minerals etc may disrupt the normal biochemical interactions. Any shortage in the availability of various amino acids and their precursers may lead to non- production of essential proteins in the organism. In some cases, it may also result in the production of defective proteins.

4. ENVIRONMENTAL FACTORS: Biochemical interactions happen only if an appropriate pH level and temperature is maintained in the body fluids. Any physical influence that may derange these physical parameters will act as pathogenic factors by deactivating protein molecules. Temperature, magnetic field, electromagnetic radiations, vibrations and various other physical influences can affect the normal biochemical processes. Physical influences actually act as pathogenic agents by producing derangement in protein conformations, which are deactivated or converted to pathogenic molecules.

5. EXOGENOUS MOLECULAR FACTORS: Chemical molecules released by infectious agents invading the organism, drugs, toxins, food articles, environmental pollutants alien proteins entering the body act as EXOGENOUS factors of disease by binding to various biological molecules such as enzymes and receptors and producing molecular inhibitions.

6. ENDOGENOUS MOLECULAR FACTORS: Antibodies, hormones, neuro-mediators, neurotransmitters, cytokines, growth factors, super-oxides, enzymes and various biological molecules of endogenous origin may cause molecular inhibitions of proteins such as enzymes and receptors, thereby acting as pathogenic agents.

It is obvious that almost all conditions of pathology we normally confront, including those resulting from genetic origin, are involved with some or other errors or absence of some protein molecules that are essential for concerned biochemical processes.

Moreover, most of such molecular errors other than of nutritional deficiencies or genetic origin, arise due to binding of some exogenous or endogenous foreign molecules or ions on the active, binding or allosteric sites of protein molecules, effecting changes in their three-dimensional conformations. A host of diseases originating from viral-bacterial infections, allergies, poisoning, drugs, food articles etc, belong to this category. Chronic diseases caused by antibodies, which are considered in homeopathy as miasmatic diseases and modern medicine as auto-immune diseases, also belong to this class. Diseases caused by emotional factors, hormones, neuro-mediators, neurotransmitters, cytokines, growth factors, super-oxides, enzymes and various biological molecules also include in this group.

KEY-LOCK MECHANISM: The most important factor we have to bear in mind when talking about kinetics of proteins in general, and enzymes in particular is their highly defined, peculiar specificity. Each type of protein molecules, or some times even some part of a single protein molecule, is designed in such a way that it can bind only with a specific class of molecules, and hence participate in a specific type of bio-chemic interaction only. This functional specificity is ensured through the peculiar three-dimensional configuration of the protein molecules, exhibited through their characteristic folding and spacial arrangement. Reactive chemical groups known as active sites, binding sites, and regulatory sites are distributed at specific locations on this three dimensional formations of protein molecules. These chemical groups can interact only with molecules and ions having appropriate spacial configurations that fits to their shape. This phenomenon can be compared with the relationship existing between a lock and its appropriate key. Just as a key with an exactly fitting three dimensional shape alone can enter the key hole of a lock and open it, molecules with exactly fitting three dimensional structure alone can establish contact and indulge in chemical activities with specific protein molecules. This key-lock relationship with substrates defines all biochemical interactions involving proteins, ensuring their optimum specificity. Obviously, any deviation in the three dimensional configuration of either lock or key makes their interaction impossible.

It has been already explained that the primary basis of any state of pathology is some deviations occurring in the biochemical processes at the molecular level. Endogenic or exogenic foreign molecules or ions having any configurational similarity to certain biochemical substrates can mimic as original substrates to attach themselves on the regulatory or the active sites of proteins, effecting changes in their native 3-D configuration, thereby making them unable to discharge their specific biochemical role. This situation is called a molecular inhibition, which leads to pathological molecular errors. It is comparable with the ability of objects having some similarity in shape with that of key, to enter the key hole of a lock and obstructing its function. As a result of this inhibition, the real substrates are prevented from interacting with the appropriate protein molecules, leading to a break in the normal biochemical channels. This type of molecular errors are called competitive inhibitions. It is in this way that many types of drugs, pesticides and poisons interfere in the biochemical processes, creating pathologic situations. Such substances are known as anti-melabolities.

To understand the ridiculous foolishness involved in the claims regarding distribution of homeopathic medicine Arsenic Album 30 as  IMMUNE BOOSTERS against covid 19, we should first of all learn what is IMMUNITY. Most disappointing thing is that most of our homeopaths are not bothered about such a learning.

In a scientifically conscious and watchful community, we cannot talk about IMMUNE BOOSTING using homeopathic medicines without explaining the biological mechanism by which such a phenomenon works. We have to be ready to face obvious hard questions.

From the ongoing discussions below, you will understand that you cannot produce IMMUNITY against particular disease without inducucing production of ANTIBODIES against the specific pathogens. It is a matter of basic scientific knowledge that production of antibodies will happen only if we introduce into the body some  protein molecules that are ALIEN to the genetic blueprint of the organism. Everybody knows ASENICUM ALBUM 30 does not contain any such molecules having antigenic properties, and as such, claiming to boost immunity using that preparation is totally baseless.

What we call IMMUNITY is actually a complex biological system functioning  in living organisms, endowed with the capacity to recognize and tolerate whatever belongs to the SELF, and to recognize and reject
what is non-self or ALIEN to its genetic blueprint.

IMMUNITY is the capability of multicellular organisms to resist harmful microorganisms invading our body. Immunity involves both specific and nonspecific components. The NONSPECIFIC components act as barriers or eliminators of a wide range of pathogens irrespective of their antigenic make-up. SPECIFIC components of the immune system adapt themselves to each new disease encountered and can generate pathogen-specific immunity.

The immune system has two components: innate and adaptive immunity. The innate immunity is present in all animals, while the adaptive immunity occurs only in vertebrates.

The innate system involves the biological mechanism for recognition of certain ALIEN molecules and stimulating of two types of innate immune responses against them, such as inflammatory responses and phagocytosis.

The adaptive immune system, on the other hand, is composed of more advanced lymphatic cells that are programmed to distinguish between specific “non-self” or alien substances in the presence of “self”. The reaction to foreign substances is etymologically described as inflammation, meaning to set on fire.

Actually, IMMUNITY is the ‘non-reaction’ or ‘exemption’ towards “self” substances.

These innate and adaptive components of the immune system create a dynamic biological environment where “health” can be seen as a physical state where the self is immunologically spared, and what is foreign is inflammatorily and immunologically eliminated.

A state of “disease” can arise when our immune system fails to eliminate ‘alien’ substances, or spare what is ‘self’.

Innate immunity, also known as native immunity, is a semi-specific form of immunity, considered as the first line of defense against pathogens, representing a critical systemic response to prevent infection and maintain homeostasis, and contributing to the activation of an adaptive immune response.

Innate immune system does not adapt to specific external stimulus or a prior infection, but relies on genetically encoded recognition of particular molecular patterns.

Adaptive immunity is also known as acquired immunity. It is the active component of the host immune response, and is mediated by antigen-specific lymphocytes.

Unlike the innate immunity, the acquired immunity is highly specific to a particular pathogen, including the development of immunological memory. Similar the innate system, the acquired system includes both humoral immunity components and cell-mediated immunity components.

Adaptive immunity can be acquired either ‘naturally’ by infection, or ‘artificially’ through deliberate actions such as vaccination.  it is associated with molecular memory of the pathogen.

Adaptive immunity is classified as ‘active’ or ‘passive’.

Active immunity is acquired through the exposure to a pathogen, which triggers the production of antibodies by the immune system.

Passive immunity is acquired through the transfer of antibodies or activated T-cells derived from an immune host either artificially or through the placenta; it is short-lived, requiring booster doses for continued immunity.

A drug substance becomes CONSTITUTIONAL MEDICINE of an individual, if it contains one or more types of chemical molecules which can “compete” with the pathogenic molecules that have produced molecular inhibitions in diverse types of biological targets causing errors in various important biochemical pathways, that are expressed through diverse trains of symptoms that belong to the classes considered to be ‘physical’ and ‘mental’ generals.

In post-avogadro dilutions, this CONSTITUTIONAL MEDICINE will contain molecular imprints of the chemical molecules contained in them, which can act as artificial binding pockets for the pathogenic molecules due to their conformational affinity, deactivate them, and remove the pathological molecular inhibitions they have produced in the body.

CONSTITUTIONAL SYMPTOMS are the expressions of disruptions in METABOLIC PATHWAYS- both anabolic as well as catabolic. These disruptions happen mainly due to inhibitions of enzymes involved in the biochemical processes in metabolic pathways caused by binding with diverse types of exogenous or endogenous pathogenic molecules. Metabolic pathways may also be disrupted due to reasons such as nutritional non-availability of essential molecules and metabolites, scarcity or over expressions of signalling molecules such as hormones and cytokines etc, which are also related with inhitions of related with their genetic expressions.

METABOLIC PATHWAYS

A metabolic pathway is a series of interdependent biochemical reactions controlled by enzymes occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites, which are modified by a sequence of chemical reactions catalyzed by enzymes. In most cases of a metabolic pathway, the product of one chemical reaction catalyzed by a particular enzyme acts as the substrate for the next. These enzymes often require dietary minerals, vitamins, and other cofactors to function. Side products of these reactions are considered waste, and normally removed from the cell.

Different metabolic pathways take place based on the position within a eukaryotic cell and the significance of the pathway in the given compartment of the cell. For instance, the, metabolic pathways such as electron transport chain, and oxidative phosphorylation etc take place in the mitochondrial membrane. Glycolysis, pentose phosphate pathway, and fatty acid biosynthesis etc occur in the cytosol of a cell.

There are two types of metabolic pathways:

ANABOLIC pathways are characterized by their ability to either synthesize molecules with the utilization of energy.

CATABOLIC pathways are involved with break down of complex molecules by releasing energy in the process.

The two pathways complement each other in that the energy released from one is used up by the other. The degradative process of a catabolic pathway provides the energy required to conduct a biosynthesis of an anabolic pathway. In addition to the two distinct metabolic pathways there is the amphibolic pathway, which can be either catabolic or anabolic based on the need for or the availability of energy.

Metabolic pathways are required for the maintenance of HOMEOSTASIS within an organism, and the flux of metabolites through a pathway is regulated depending on the needs of the cell and the availability of the substrate.

The end product of a metabolic pathway may be used immediately, initiate another metabolic pathway or be stored for later use. The metabolism of a cell consists of an elaborate network of interconnected pathways that enable the synthesis and breakdown of molecules.

Each metabolic pathway consists of a series of biochemical reactions that are connected by their intermediates. The products of one reaction are the substrates for subsequent reactions, and so on. Metabolic pathways are often considered to flow in one direction. Although all chemical reactions are technically reversible, conditions in the cell are often such that it is thermodynamically more favorable for flux to proceed in one direction of a reaction. For example, one pathway may be responsible for the synthesis of a particular amino acid, but the breakdown of that amino acid may occur via a separate and distinct pathway.

Glycolysis was the first metabolic pathway discovered. As glucose enters a cell, it is immediately phosphorylated by ATP to glucose 6-phosphate in the irreversible first step. In times of excess lipid or protein energy sources, certain reactions in the glycolysis pathway may run in reverse to produce glucose 6-phosphate, which is then used for storage as glycogen or starch.

Metabolic pathways are often regulated by feedback inhibition.

Some metabolic pathways flow in a ‘cycle’ wherein each component of the cycle is a substrate for the subsequent reaction in the cycle, such as in the Krebs Cycle.

Anabolic and catabolic pathways in eukaryotes often occur independently of each other, separated either physically by compartmentalization within organelles or separated biochemically by the requirement of different enzymes and co-factors.

A CATABOLIC PATHWAY is a series of reactions that bring about a net release of energy in the form of a high energy phosphate bond formed with the energy carriers adenosine diphosphate (ADP) and guanosine diphosphate (GDP) to produce adenosine triphosphate (ATP) and guanosine triphosphate (GTP), respectively. The net reaction is, therefore, thermodynamically favorable, for it results in a lower free energy for the final products. A catabolic pathway is an exergonic system that produces chemical energy in the form of ATP, GTP, NADH, NADPH, FADH2, etc. from energy containing sources such as carbohydrates, fats, and proteins. The end products are often carbon dioxide, water, and ammonia. Coupled with an endergonic reaction of anabolism, the cell can synthesize new macromolecules using the original precursors of the anabolic pathway. An example of a coupled reaction is the phosphorylation of fructose-6-phosphate to form the intermediate fructose-1,6-bisphosphate by the enzyme phosphofructokinase accompanied by the hydrolysis of ATP in the pathway of glycolysis. The resulting chemical reaction within the metabolic pathway is highly thermodynamically favorable and, as a result, irreversible in the cell.

Cellular respiration is a core set of energy-producing catabolic pathways occuring within all living organisms in some form. These pathways transfer the energy released by breakdown of nutrients into ATP and other small molecules used for energy (e.g. GTP, NADPH, FADH). All cells can perform anaerobic respiration by glycolysis.

Additionally, most organisms can perform more efficient aerobic respiration through the citric acid cycle and oxidative phosphorylation. Additionally plants, algae and cyanobacteria are able to use sunlight to anabolically synthesize compounds from non-living matter by photosynthesis.

In contrast to catabolic pathways, ANABOLIC PATHWAYS require an energy input to construct macromolecules such as polypeptides, nucleic acids, proteins, polysaccharides, and lipids. The isolated reaction of anabolism is unfavorable in a cell. Thus, an input of chemical energy through a coupling with an exergonic reaction is necessary. The coupled reaction of the catabolic pathway affects the thermodynamics of the reaction by lowering the overall activation energy of an anabolic pathway and allowing the reaction to take place. Otherwise, an endergonic reaction is non-spontaneous.

An anabolic pathway is a biosynthetic pathway, meaning that it combines smaller molecules to form larger and more complex ones. An example is the reversed pathway of glycolysis, otherwise known as gluconeogenesis, which occurs in the liver and sometimes in the kidney to maintain proper glucose concentration in the blood and supply the brain and muscle tissues with adequate amount of glucose. Although gluconeogenesis is similar to the reverse pathway of glycolysis, it contains three distinct enzymes from glycolysis that allow the pathway to occur spontaneously.

1. Feedback from Dr. Suresh S Patel. Om Shree clinic, opp: Gawara tower, Mochiwad Road, Khambhat. Gujarat.388620, Ph: 9879062647,  regarding his experience with MIT formulation CEPHAMIT in the treatment of chronic MIGRAINE:

“A female patient, Age: 38 yrs. Migraine type headache since last 3yrs. Every 15 to 20 days repeats the attack. Pain in one side of skull, with vomiting & feeling of nausea. Has been taking painkillers & anti-migraine tabs & Tranquilizers,  but only temporarily relief. Gave Nat.Mur 1M  one dose, and
MIGROMIT 10drops  tid .  2 bottles of migromit completed,  till date no occurrence of headache. Patient feel very well. Thanks MIT formulation.”

2. Feedback from Dr.Pulkit Gupta,  Homoepathic clinic,  Aghwanpur,  moradabad, Uttarpradesh,
+91 96544 99884, regarding his experience with MIT formulation
BRONCHOMIT:

“Patient a child of aged 6 years of  age,  suffering from broncho spasmodic cough with vomiting since 2-3 days.  I started with BRONCHOMIT 10 drops 3 times a day with indicated  remedy.  All the cough symptoms was no more. Child started playing as usual which he used to. Thanks to MIT.”

3. MIT IN PERSISTENT COUGH:

Feedback from Dr Arshad pathan,  Life Care Clinic, Bus stand,  Ambua,  Alirajpur,  Madhya pradesh, Ph 7869230555, regarding his experience with MIT formulation BRONCHOMIT in a case of persistent COUGH.

“Male patient, age 53 years, suffering from cough since 5-6 months.  Taken treatment from various doctors ( including chest physician). All investigations where normal,  includind x ray.

Patient came to me. Chest was clear and no any abnormal sounds. I started with BRONCHOMIT 5 drops tds  then in just 4 days there is no cough…”

4. MIT IN LUMBOSACRAL SPONDYLOSIS

A feedback from Dr Manisha Deshmukh, Pune, Maharashtra, Ph: 98221 18479, regarding her experience with MIT formulations in a case of LUMBOSACRAL SPONDYLOSIS:

“A 62 yrs old female patient, suffering from Cervical and Lumbosacral spondylosis since 2 years

Had visited my hospital on 20th Jan 2020. Was given Spinomit and spondomit 10 drops bd for 2 months

Later she visited us on 10th Apr 20 informing all symptoms cleared.

On 1st Sep 20, patient reported for mild pain in left leg and pain in Lt knee joint
She was prescribed Spinomit, Arthromit and Gerimit 10 drops bd  for 15 days, after she is fine till date with no complaints”

5. Feedback from Dr Arshad pathan,  Life Care Clinic, Bus stand,  Ambua,  Alirajpur,  Madhya pradesh, Ph 7869230555, regarding his experience with MIT formulations GYNOMIT and AMENMIT in a case of AMENORRHEA:

“Female patient, age 40, came to me with c/o amenorrhea since 6 months.  All investigations were normal ( usg,  blood reports and harmonal reports).  Also taken treatment from many gynecologists. But there is no any result.

I started with with GYNOMIT and AMENMIT.  Within just  1 month normal mentrual cycle came…”

6. Feedback from Dr.Pulkit Gupta,  Homoepathic clinic,  Aghwanpur,  moradabad, Uttarpradesh,
+91 96544 99884, regarding his experience with MIT formulation ARTHROMIT:

“Female patient aged 48 years was complaining of joint pain since 2-3 years. I started with ARTHROMIT, 10 drops 3 times a day for 2 weeks.  Joint pain was no more, thanks to MIT protocol.

I have also tried PYROMIT, DYSMENMIT etc in other cases, and  all worked well. Thankyou sir.”

7. A feedback from Dr Manisha Deshmukh, Pune, Maharashtra, Ph: 98221 18479, regarding her experience with MIT formulations ALLERMIT and RHINMIT:

“A lawyer aged 28 yrs, was suffering from allergic rhinitis since August 2019, reported in my clinic on 18th November 2020.

Allermit and Rhinimit 10 drops bd was dispensed.

Surprisingly she has called me on 21st November, informing me about all symptoms of allergic rhinitis gone.

 Thank you Chandran Nambiar sir,  for introducing me to this wonderful system of medicine in a scientific way.
Looking forward for more such patients to be getting cured in our clinic.”

8. Here is a great feedback from Dr.G.Madhu sudhan Bsc.BHMS, Balaji clinic, Hoskote, Bangalore, 9980509963, regarding his experience with MIT formulation CEPHAMIT in chronic headache:

“CEPHAMIT has excellent result in headache.

A Lady aged 39 years consulted me for her complaint of headache. Headache since 2 to 3 years. Took treatment for the same…she tried allopathy..ayurveda…even homeopathy…but no permanent relief. She was fedup with all these things..she relied on croc in..anacin..or paracetamol like analgesics..

She came to me without much confidence… first I ruled out   is there any sinus problem & then I send her for eye testing..nothing wrong in that..and checked for BP to rule out hypertension & blood check up for hormonal changes…everything is alright..she is from well settled family..no financial burden..no anxiety…no sleeping problems.(.sleep disturbance is there because of headache..once if she takes analgesics that is also ok).

I simply prescribed CEPHAMIT 10drops BD. She got relief within 8days. Suggested to continue for one month. In between that frequency of episodes of her headache reduced, and having sound sleep also. From last 2 months she had not took single analgesic. Really CEPHAMIT is an excellent remedy for headache.  Thank you sir.”

9. Dr Manojkumar Chajjed, Nashik, Maharastra ph- 7588037280 writes about his experience with MIT formulation CEPHAMIT :

“A Female 20 year old ,  43kg,  had severe Head pain during lockdown time April. She can’t sleep. She cunsulted Physician but not get relief. I give CEPHAMIT 10 drops tds.  Within 10 day she got relief.

She has till now no any complaint about head pain in routine working.

Really MIT FORMULATIONS work wonderful. Thank you Sir ”

10. Feedback from Dr.Redage Sumit B.
BHMS, Nashik, Maharashtra, Ph- +91 95273 74951, regarding his experience with MIT formulation ARTHROMIT in a case of OSTEOARTHRITIS:

“A 30 years old lady having c/o joint pain treated with Arthromit. #Promising Result with Scientific Homoeopathy

Patient Testimonial:-
“I have been suffering from joint pain for the last 1 year. Even taking a lot of pain Killers didn’t alleviate the problem. It also made it difficult for me to do my daily chores. Finally I took Homoeopathic treatment from Dr.Redage Sir. Within 4 days of starting medication I started to feel better. Now I can manage my pain without a single painkiller. Now I can also do my daily work. Thank you Doctor.”

Dx,
Osteoarthritis

Treatment Given:-

Rx,
Arthromit 5 drops (in tsp water) × TDS for 15 days

Contact Details:-
Dr.Redage Sumit B.
BHMS(MUHS,Nashik)
Reg.No.72347
Email Id:- sumitredge@gmail.com
Mob.No.:- +91 95273 74951
Address :- Vasmat road, Parbhani(Maharashtra)
Pin code:-431401“

11. A feedback from Dr Partha Ghosh, Siliguri,West Bengal, ph- 8250487994, regarding his experience with MIT formulations BRONCHOMIT in a chronic BRONCHITIS patient: “Male retired Govt employee,  age 61, male.  Service time was smoker. Bronchitis patient. Tremendous problem of breathing asthama
After BRONCHOMIT, he is now totally ok, where allopathy plus hospitalized conditions occurred earlier. Now no complaints.  Excellent MIT!”

Patients around West Bengal may contact Dr Partha Ghosh over 8250487994  for expert treatment according to MIT PROTOCOL.

He has got a good stock of MIT FORMULATIONS. Doctors can contact him for knowing more about their use and buying them.

12. A feedback from Dr Partha Ghosh, Siliguri,West Bengal, ph- 8250487994, regarding his experience with MIT formulations BRONCHOMIT in a chronic BRONCHITIS patient:

“Male retired Govt employee,  age 61, male.  Service time was smoker. Bronchitis patient. Tremendous problem of breathing asthama
After BRONCHOMIT, he is now totally ok, where allopathy plus hospitalized conditions occurred earlier. Now no complaints.  Excellent MIT!”

13. A feedback from Dr Dattaraj, Goa,  97645 99530, regarding his experience with MIT formulations BRONCHOMIT and PULMOMIT in relieving a case of acute ASTHMA: “Hello Sir, I did a home visit of 55yrs old female. Presented with severe wheezing since yesterday night. Spo2 80% , RS- B/L Rhonchi.  I had given BRONCHOMIT 10drops with PULMOMIT 10drops every 15mins. Plus steam inhalation by adding 10 drops of both. Pt improved drastically. Spo2 from 80% came to 94% within 1/2hour.”

14. Dr Alokesh Bhattacharya, Hooghly, West Bengal, Ph- 91 93309 49695, has shared a feedback regarding his experience with MIT FORMULATIONS:

“Good morning sir.  I would like to share an outstanding successful case of dysmenorrhoea treatment wit MIT FORMULATIONS.

Patient was suffering from dysmenorrhoea since her menerche. Now she is 24 yrs. Unmarried . She has tremendous maddening pain from 1st day  of period to 5th day.

She was always taking diclofenac 
for this complaint, though she was taking constitutional  homoepathic medicine as well as palliative homoeopathic medicine during pain without any effect. And she was  bound to take analgesics.

But this time she took ALGIMIT AND DYSMENMIT alternately for 5days during her period, and she required no analgesic. Its great success.

I have also got good results from ALLERMIT, ALGIMIT and PYROMIT in different cases”.

15. Feedback from Dr Partha Ghosh, Siliguri, West Bengal,  Ph- 8250487994, regarding his experience with the MIT formulation SPONDOMIT:

“Spondomit
Tremendous result.

Patient a female house wife. Cervical spondilysis last 20 years,  after birth of her first male child. Stiffness of neck associated with back pain, hand pain and vertigo. They were regular symptoms. Gave ALGIMIT and SPONDOMIT. Within 2 days no pain. Regular work. Now she is coming to me with old songs in singing, that I am completely fine.”

Great mit formulations!”

16. Dr Pravin Prajapati , Mehsana, Gujarat, phone +91 97233 95545, writes about his experience with MIT FORMULATIONS :

“A Female 50 year old , diabetes, over  weight,  90 kg,  had severe lumbar pain during lockdown time April. She can’t sleep. She cunsulted two orthopaedic Doctors within 10 day but no relief. Then  I have gave her SPINOMIT and ALGIMIT. She got a relief from pain within 2 days.  10 drop 6 time. After 2 day 4 time 10 drop. To 15 day.

She has till now no any complaint about lumbar pain in routine working.

I HAVE GOT WONDERFUL RESULTS IN COLD , FEVER  FROM ‘CORYMIT’ AND ‘PYROMIT’ during this VIRAL SEASON
in many patients.

I have also got results in allergic respiratory complaints from ALERMIT in  MANY PATIENTS.

Really MIT FORMULATIONS work wonderfully.”

17. Feedback from Dr Sandeep Selvinus MD, Andhrapradesh, ph- 99488 41285,  regarding his experience with IBSMIT in the treatment of IRRITABLE BOWEL SYNDROME:

“I am Grateful to you for providing such a good combination. A patient of mine suffering from IBS problem since 2 yrs got her problem recovered 80% within 1month after I prescribed “IBSMIT” alone only .

Thank you sir,
Regards
Dr.sandeep selvinus, M.D
ANDHRA PRADESH.”

A lot of SCIENTIFIC SEMINARS are being conducted all over the world. A lot of “scientific papers” and “lectures” are presented by “eminient homeopaths” and “homeopathy researchers”.

I have some simple questions to them:

How can you discuss “MODUS OPERANDI” of post-avogadro diluted homeopathic drugs, without discussing regarding the ACTIVE PRINCIPLES they contain?

MIT or MOLECULAR IMPRINTS THERAPEUTICS is a scientific hypothesis trying to explain homeopathy.

As per this hypothesis, potentization involves a process of Molecular Imprinting in water-alcohol supra-molecular matrix using drug molecules as templates, by which nanocavities or molecular imprints bearing the spacial conformations of drug molecules in a negative orientation are produced. Drugs potentized above avogadro limit contain these MOLECULAR IMPRINTS as their active principles, which can act as artificial binding pockets for the pathogenic molecules.

One of the main criticisms against this hypothesis was that molecular imprinting could be done only in POLYMERS, and since water is not a polymer, molecular imprinting could not be done in water-alcohol matrix. Even though I had scientifically explained why water is considered a polymer-like substance, many people were reluctant to accept my explanations. Now comes a great research work that has scientifically proved that “Liquid water is a dynamic polydisperse branched polymer. This work done by a team led by William A. Goddard III and Saber Naserifar is a great breakthrough in water research, which will of course be of course a decisive help in establishing THE concept MOLECULAR IMPRINTING involved in homeopathic potentization as hypothesised by MIT.

According to the researchers, they have proved through quantum mechanics force field molecular simulations that Liquid water is a dynamic polydisperse branched polymer. They have showed that when ice undergoes melting, the number of SHBs (strong hydrogen bonds) drops quickly to two in liquid water. These two SHBs couple into chains containing over 150 water molecules, resembling a branched polymer, where polymer branches evolve dynamically. Authors expect that this dynamics-branched polymer paradigm may explain long-standing puzzles of water, and may explain the observed angular correlations in water.

You can read the research paper on this link: .https://www.pnas.org/content/116/6/1998

I have before me a research paper titled “covid-19 research Homoeopathy- Efficacy of Arsenicum Alb 30c for upregulating immunological markers among residents of covid-19 related hot spot areas in Pathanamthitta, Kerala”, recently published by Dr M V Thomas and coworkers, including some of the senior homeopaths from kerala.

HAHNEMANN UTILIZED THE CONCEPT OF “DYNAMIC ENERGY” DUE TO HIS “INABILITY” TO EXPLAIN CERTAIN PHENOMENA HE OBSERVED “BY ANY OTHER MANNER”!

Read Hahnemann saying in Organon : Aphorism 11 : Sixth Edition: Foot Note:

“Is it then so utterly impossible for our age celebrated for its wealth in clear thinkers to think of dynamic energy as something non-corporeal, since we see daily phenomena which cannot be explained in any other manner?”

It obviously means, he would not have thought about the concept of ‘dynamic energy’, if it was possible for him to explain these “daily phenomena” “in any other manner”!

Hahnemann was compelled to ‘think’ about ‘dynamic energy’, only because he saw many daily phenomena which he could not explain in “any other manner”‘. It amounts to a humble confession by the master:

Which were those “daily phenomena” Hahnemann observed, “which cannot be explained in any other manner” that prompted him to think about a “dynamic energy” that is something “non-corporeal”?

Further he gives in the same footnote a list of “daily phenomena” which he could not explain by any other manner other than “dynamic energy” as follows:

“If one looks upon something nauseous and becomes inclined to vomit, did a material emetic come into his stomach which compels him to this anti-peristaltic movement? Was it not solely the dynamic effect of the nauseating aspect upon his imagination?”

“if one raises his arm, does it occur through a material visible instrument? a lever? Is it not solely the conceptual dynamic energy of his will which raises it?”

“Our earth, by virtue of a hidden invisible energy, carries the moon around her in twenty-eight days and several hours, and the moon alternately, in definite fixed hours (deducting certain differences which occur with the full and new moon) raises our northern seas to flood tide and again correspondingly lowers them to ebb. Apparently this takes place not through material agencies, not through mechanical contrivances”

“we see numerous other events about us as results of the action of one substance on another substance without being able to recognize a sensible connection between cause and effect”

“dynamic effect of the sick-making influences upon healthy man, as well as the dynamic energy of the medicines upon the principle of life in the restoration of health is nothing else than infection and so not in any way material, not in any way mechanical”

“Just as the energy of a magnet attracting a piece of iron or steel is not material, not mechanical”

“One sees that the piece of iron is attracted by one pole of the magnet, but how it is done is not seen.”

“This invisible energy of the magnet does not require mechanical (material) auxiliary means, hook or lever, to attract the iron. The magnet draws to itself and this acts upon the piece of iron or upon a steel needle by means of a purely immaterial invisible, conceptual, inherent energy, that is, dynamically, and communicates to the steel needle the magnetic energy equally invisibly (dynamically).”

“The steel needle becomes itself magnetic, even at a distance when the magnet does not touch it, and magnetises other steel needles with the same magnetic property (dynamically) with which it had been endowered previously by the magnetic rod”

“a child with small-pox or measles communicates to a near, untouched healthy child in an invisible manner (dynamically) the small-pox or measles, that is, infects it at a distance without anything material from the infective child going or capable of going to the one to be infected”

“A purely specific conceptual influence communicated to the near child small-pox or measles in the same way as the magnet communicated to the near needle the magnetic property.”

These were the “daily phenomena” which he could not explain by “any other means”, and compelled him to explain using the concepts of “dynamic energy”.

1. Hahnemann could not scientifically explain how limbs are raised at will- and hence, he explained it using dynamic energy.

2. Hahnemann could not scientifically explain why people get nauseated by seeing others vomit- and hence, he explained it using dynamic energy.

3. Hahnemann could not scientifically explain how measles and chicken pox are transmitted- and hence, he explained it using dynamic energy.

4. Hahnemann could not scientifically explain why earth revolves around sun- and hence, he explained it using dynamic energy.

5. Hahnemann could not scientifically explain the phenomena of high and low ebbsl- and hence, he explained it using dynamic energy.

6. Hahnemann could not scientifically explain how a magnet attracts an iron needle- and hence, he explained it using dynamic energy.

7. Hahnemann could not scientifically explain how a steel needle gets magnetized in the vicinity of a magnet – and hence, he explained it using dynamic energy.

8. Hahnemann could not scientifically explain the phenomenon of life – and hence, he explained it using vital force and dynamic energy.

9. Hahnemann could not scientifically explain disease and cure- and hence, he explained it using dynamic energy.

10. Hahnemann could not scientifically explain symptoms and drug proving- and hence, he explained it using dynamic energy.

11. Hahnemann could not scientifically explain how substances get medicinal property- and hence, he explained it using dynamic energy.

12. Hahnemann could not scientifically explain how potentization really worksl- and hence, he explained it using dynamic energy.

13. Hahnemann could not scientifically explain how potentized drugs act- and hence, he explained it using dynamic energy.

Some homeopaths think that therapeutic actions of post-avogadro diluted homeopathic medicines could be explained using the concepts of QUANTUM PHYSICS.

They should bear in mind that Quantum physics is a branch modern science that deals with the behaviour of matter and light on the atomic and subatomic scale. It attempts to describe and account for the properties of molecules and atoms and their constituents—electrons, protons, neutrons, and other more esoteric particles such as quarks and gluons.

Attempts of explaining homeopathy using QUANTUM PHYSICS comes from the idea that drug substances are converted to SUBATOMIC PARTICLES and ENERGY during the process of homeopathic potentization.

The funny thing is that those who now comes with QUANTUM THEORIES of homeopathy were so far talking about NANOPARTICLE research in homeopathy!

They should understand, NANOPARTICLES has nothing to do with QUANTUM PHYSICS. Science of nanoparticles deas with the study of SUPRA-MOLECULAR and SUPRA-ATOMIC FORMATIONS of matter, where as quantum physics deals with the study of SUB-ATOMIC particles and forces. First of all you have to decide whether it is “subatomic particles” or “nanoparticles” you are talking about.

Anybody with high school level knowledge of science is aware that complex chemical molecules contained in drug substances cannot be converted to subatomic particles or energy particles by the process of potentization. With the minimal mechanical energy involved in “shaking”, you cannot break the very strong covalent bonds that hold atoms together in a chemical molecule.

What a ridiculous nonsense it will be if anybody says he can split a simple water molecule into oxygen and hydrogen atoms by “shaking” it? It is wonderful to see that our homeopathy “scientists” are imagining about converting matter into energy by the simple mechanical process of shaking involved in potentization! To convert drug substance into energy, they have split molecules into atoms, atoms into subatomic particles, and then subatomic particles into energy particles. One have to be an idiot to believe that it is happening during potentization!

Even if somebody could split drug molecules into atoms and subatomic particles, how can those particles retain the medicinal properties of complex drug molecules? Medicinal properties of drug molecules are due to their peculiar structure and chemical properties. How can an individual atom or subatomic particle retain the chemical properties of complex drug molecules?

Once the complex molecules are divided into constituent atoms, their molecular level properties are lost. Once the atoms are split into subatomic particles, their atomic level properties are lost. When matter is converted into energy, it will be ENERGY only. There cannot be a NUX VOMICA energy or SULPHUR energy once they are converted to energy form!

Same way as our SCIENCE-STARVED homeopaths swallowed the nonsense “nanoparticle theory” without asking a single question, they will swallow this QUANTUM PHYSICS THEORY OF HOMEOPATHY also! Especially when BIG scientists are talking it!

Arsenic Album or Arsenic Trioxide is a chemical substance that can inhibit more than 200 essential enzymes in our body involved in diverse types of biomolecular processes related with genetic transcription, metabolism, energy conversions etc etc.

This is due to the ability of Arsenic ions to bind to the cysteine radicals which are part of active sites all enzymes. Almost every biochemical pathways in the living body are deranged by the action of arsenic. This is the reason why the homeopathic materia medica of arsenic album is so rich with symptoms associated with almost all organs and systems of the body.

It is an already established fact that during viral infections, persons having high levels of arsenic in their body are prone to develop serious complications such as respiratory failure, acute myocardial degeneration, renal failures, liver failures, multiple organ failures etc faster than those having low arsenic levels.

My suggestion to the experts involved in covid 19 research is that determination of arsenic levels in the body of covid patients should be made mandatory, so that high risk people could be identified and better care provided.

Arsenic content may be high in people due to living in certain areas, consuming arsenic rich ground water, cigarette smoking, eating unpolished rice, prawns and crabs, exposure to arsenic containing environments, etc etc. Arsenic may enter the body through contaminated liquors, Chinese, Ayurvedic, unani or Herbal preparations, industrial exposures, chemically treated wooden furniture etc also. Arsenic content will naturally be high in aged people, as it has a tendency to accumulated in the body over years through exposures.

Researchers working upon arsenic toxicity problems in certain arsenic affected countries have already proved that ARSENIC ALBUM 30 can antidote and reverse the chronic effects of arsenic toxicity, and remove the symptoms.

Arsenic Album 30 contains MOLECULAR IMPRINTS of arsenic trioxide molecules. Molecular imprints are three dimensional nanocavities formed in water-alcohol supra-molecular matrix through a host-guest interactions between templates and diluent medium during the process of homeopathic POTENTIZATION.

Molecular imprints of arsenic trioxide contained in Arsenicum Album 30 can act as artificial binding pockets for arsenic ions and deactivate them, thereby removing the molecular inhibitions they have produced in the enzyme systems of the body.

By using Arsenicum Album 30 in sufficient quantities and frequencies to provide molecular imprints in optimum levels, it will be possible to prevent dangerous complications and multiple organ failures in covid 19 patients, so as to prevent the chances of morbidities due to the disease. Covid 19 deaths could prevented by use of Arsenic Alb 30.

I don’t know how to get this vey important message reach the right persons in right time, or how to convince the scientific basis of this approach described above.

A word to homeopaths : Homeopaths currently involved in distribution of Arsenicum Album 30 should realize the hard truth that the dosage you are giving now is actually of no use. 4 or 5 medicated sugar pills you give now cannot provide the sufficient quantity of molecular imprints required to produce desired biological effects. To ensure optimum protection, medicine should be used in drop doses at least twice a day until the epidemic threat is over.

Please understand, it is not any mysterious “dynamic energy” or “vibrations” that work in our potentized drugs. It is MOLECULAR IMPRINTS, that act as “artificial binding pockets” for pathogenic molecules, and deactivate them.

Many homeopaths refer to a link as the most scientific and authoritative reference for research evidences in favor of homeopathy. This article titled “Beyond Substance” by Norman Allan, Ph.D.is about the much discussed findings regarding the so-called “ghost-DNA” molecules in ultra-diluted aqueous solutions of viral DNA. This work was referred to the name of Professor Mounir AbouHaidar and his colleagues, Dr. Mohammed Eweida and Michael Dobbs. Exactly, this ghost DNA concept is same as that of Luc Montagnier. If you read the article carefully, you will understand how clever our ‘pseudoscientists’ are in hijacking scientific studies and misuse them for pseudoscientific explanations of homeopathy. Hence, I think it is worth analyzing the observations and conclusions of this article in detail.  http://www.normanallan.com/Sci/bs.html.

I find this article is a classical example of how scientific studies are misused for pseudo-scientific explanations of homeopathy.

“The team found that a solution of viral DNA, diluted beyond substance in the manner of homeopathy, can physically bind its substantial, molecular, complementary strand. This implies that the water “remembers” the substance that was in it. It behaves as though the DNA – even though diluted beyond substance – were still there. The ramifications of this phenomenon deeply effects ours understanding of physics, medicine, and of psychology, and as I hope to explain may prove to be a key to our understanding consciousness”.

“In Prof. AbouHaidar’s viral assay a solution of DNA, the genetic ribbon – even after it has been serially diluted until there was no substance left – binds its labeled complementary strand. This means water can be patterned; can carry a signal, and in this sense “remembers”. Water prefers to be ordered, to be patterned, prefers this to our usual conception of liquid as random. Water is stressed by, rather than enjoying amorphous chaos. It prefers to be organized, to behave like a crystal. So water takes whatever substance we put in it, be that salt, or sulphur, or viral DNA, as a seed from which to organize a pattern”.

Based on this research finding, the author tries to explain the homeopathic potentization according to his speculative theorizations.

He expects that if the observed “phenomenon can be replicated, we have a scientific revolution, a paradigm shift, possibly as vast as the discovery of electricity some two hundred and fifty years ago: vast because, as with electricity, it shows us whole new dimensions of order underpinning the phenomenal world, and there is no predicting where all of this may lead”.

The author, himself a physical scientist, explains how he was attracted to this work:

“Jacque Benveniste was a prominent French immunologist, chief immunologist at the government’s research institute, INSERM. When two of his research assistants asked him if they might conduct an experiment into homeopathy, believing a happy coworker is a good coworker, Benveniste said they might. They showed the results to Benveniste, and he became curious.

If you take an antigen, and dilute it homeopathically – again, diluted until there is no substance – it will still generate an immunological response in certain white blood cells. In this case Benveniste, and his colleagues, were looking at basophils.

Benveniste took these findings to the most prestigious scientific journal, Nature. Because of Benveniste’s prominence Maddox, the editor of Nature, said he would publish the work if Benveniste could find three reputable laboratories that could replicate his findings. “That should get rid of him,” thought Maddox.

Bruce Pomeranz, of the University of Toronto, was one of the researchers that “replicated” the work, along with labs in Milan and Tel Aviv.

In June 1988 the journal Nature, the gatekeeper of scientific orthodoxy, published Benveniste’s ultradilution (homeopathy) paper. The implications of this work are revolutionary, a paradigm shift it there ever was one. There are a lot of people who would rather fight than shift. Nature, the journal, as part of their publishing arrangement with Benveniste, sent a team to investigate his lab. The team included Randy the Magician, to look for sleight of hand, Walter Stewart, a biologist and statistician who had made his reputation as a figure crunching fraud-detector, and the editor, Maddox himself, who had a background in physics. It did not, however, include a cell biologist who might understand the nuances of Benveniste’s experiment. The team had already made up their minds (as Walter Stewart wrote in “Omni”). They knew there had to be a problem with the experiment because in their view the experiment was impossible. In the lab, Beneviniste and his team demonstrated the phenomenon to them three times, but the Nature team had determined before hand that it was an impossible experiment, and not knowing what else to doubt they decided that they couldn’t trust Beneveniste”blind”. The visiting team therefore insisted on adding their own “blind” to the procedure. To do this they introduced an extra manipulation of the samples (they moved the samples into new tubes). Of course this added procedure might or might not effect the outcome of an already delicate experiment. The investigating team sealed their extra code in an envelope, wrapped that up in silver foil (to foil X-ray eyes), and stuck it on to the ceiling of the lab with a video camera trained on it.! When, in this one trial, this new variation of the experiment no longer worked, Maddox announced that the whole affair was a delusion, or a fraud. Such is the stature of the journal, Nature, that the “expert’s” pronouncement was treated with gravity. “In our view, ultradilution should not work. Therefore it does not. Trust us. We’ve looked. We’ve tried it.” (I paraphrase.) This was all every unscientific, yet here the matter rests. (Work by Professor M Roberfroid, Madeleine Ennis, and colleagues, has since vindicated Beneviniste’s work and homeopath.)

Now our name was on this controversial Benveniste ultradilution paper, and we’re a very respectable laboratory, so there was a large section of the world, at least here in Canada, that looked to us to see what we’d finally have to say on the matter. “We have promising preliminary results,” was all the Professor could say. That, and “No comment.” So when Prof. AbouHaidar’s team stumbled on the incredible that DNA diluted (one part in ten) eighteen or twenty five times (diluted beyond substance) still binds its complementary strand – they came to see us”.

This was how by Norman Allan, Ph.D, author of present article became involved in this work.

The work was done as follows:

“Prof. AbouHaidar is a virologist; a Professor with tenure at the University of Toronto. Professor AbouHaidar was working on a viral assay. You’d take a plant from a field – he was working with potatoes – grind it up, run it through the Professor’s assay, and it would tell you whether there was any of a particular virus present in those potatoes. It works like this: you take a virus, which in this case was a DNA virus, and you “digest it”, splitting each bit of viral DNA into two single complementary strands. Then you divide this digest into two parts. At this point the two parts are (statistically) identical. Take one half of this now single stranded DNA and call it the “target”. Take the other half and call it the “probe”.

The target is spotted out on a filter paper – that is to say, you put a drop of it on a microfilter to make a spot. Then you dilute what’s left one part in ten, and put a drop of the dilute solution at a second spot. Then dilute again one part in ten, and spot it out again. Keep diluting and spotting out the successive dilutions. This is to test how sensitive the assay is. After all, we may be looking for a little bit of virus in a whole field of potatoes. We need a sensitive assay.

Having spotted out all these successive dilutions, we take the filter paper and bake it at 80 degrees centigrade. After baking, the target won’t wash off. Next let us consider the probe. The probe, remember, in this explanation, the probe is made up of the same single stranded viral DNA fragments. These we’re going to label so we can see them. We mix them with avidin-biotin. The avidin binds to the DNA, and the biotin will bind to a stain, so we’ll get a dark spot where our DNA-avidin-biotin binds the stain.

Now we take our probe and wash it over the targeted filter paper. Where the DNA in the probe finds its complementary strand in the target it binds to it. Next we wash the probe and target, and only where the probe has bound to its complementary strand will there be any of the probe be left. The rest is washed away. Then we ‘develop’ the probe/target filterpaper with our stain. Only where the labeled probe has bound to the target will we see any stain. In the test as set it up, the stain gets lighter and lighter with each dilution. It’s dark, almost black, in the first couple of dilutions, but fades out of sight at about the seventh dilution.

That’s the assay AbouHaidar was refining. (Actually, it’s Dr. Southern’s dot-blot test, so it’s called “Southern blot”, though Dr. Western’s “Western dot-blot” predates it and is more widely used.). Mohammed Eweida was a postdoc working in Prof. AbouHaidar’s lab with this Southern blot assay. Mohammed Ewieda wasn’t very happy about his situation. I don’t know why, but he was out of there: he was off to the Karolinska Institute in Stockholm in the summer: and so, perhaps to kill time, he spotted out the dilutions eighteen times, even though the staining was lost to sight at the seventh, and and he got a dark spot at the eighteenth dilution!

“Look at that,” said Dr. Eweida to Michael Dobbs, a postgraduate student working in the lab. Some months before Mike Dobbs had been to Jacque Benveniste’s lecture on ultradilution. (In Homeopathy substances are diluted beyond the infinitesimal till there’s no substance left, which is what is meant by “ultradilution”.) So, when Mohammed showed Michael his anomalous result with an unexpected spot at the eighteenth dilution Michael thought, incredulously, “ultradilution”. “Eh, Mohammed,” he said. “Do that again.” Dr. Eweida repeated the viral assay, this time taking it out to the fiftieth decimal (one in ten) dilution. (That’s 10-50 where ten to the minus 30 is like a drop in the ocean, and 10-37 is like a drop in a million oceans. At 10-26 we pass “Avagadro’s number [which relates to the number of molecules in a “gram molecule”] and would no longer expect to find a single molecule in a gram.) Again there was a dark spot that shouldn’t be there at the eighteenth dilution, and now there were also stained spots at the 19th dilution, and the 25th and 26th, and the 38th, and 43rd dilution, but not at the dilutions in between. At the 25th and 26th dilutions there is certainly no substance left in the solution. We have passed Avagadro’s number. There is no DNA left in the target. And yet the undiluted complementary strands in the probe (labeled with avidin-biotin) binds to the target! They can not be binding to a substance, not to molecular DNA. They may be binding to a signal, an electrical signal imprinted into the nitrocellulose. They are binding to something!

At first sight, to some, this has seemed to contradict classical science. “How can water, with nothing in it, remember what was there formerly, but is no longer there?” But here were Prof. AbouHaidar and Dr. Eweida, here they were with these filterpapers, dozens of them, with dark spots at the 18th and 19th dilution, and the 25th and 26th. Sometimes the pattern moved a little: sometimes only the 18th turned dark, once it was the 17th.

Well, Prof. AbouHaidar when he first saw it, suspected a joke. And when Dr. Eweida repeated it yet again, Menir AbouHaidar suspected a hoax. So he tried it himself, and there it was. No hoax.

What to do next? One of the next things that Prof. AbouHaidar did was to come and see us, Dr. Pomeranz and his research team. From here on in I’m going to call Dr. Pomeranz, the Professor. The Professor’s lab (where I had worked for seven years) was one of the labs that replicated Benveniste’s work with ultradilute antigens. The Professor’s name was on Benveniste’s controversial paper, so Prof. AbouHaidar came to talk to us, in confidence, to hear what we could tell them. “Do it again,” we said. And they did.

What does all this mean? It suggests a multitude of things. First let’s look at the patterning of water. If you put, say, one part salt in a hundred parts of water, it seems that the salt will pattern the water – the water mirrors the salt’s “vibration”. Certainly with Prof. AbouHaidar’s DNA we seem to see an electrical patterning that comes back into register with the original space/charge patterning at the 18th dilution.”

Based on these observations, the author tries to explain homeopathy as follows:

“Now if homeopathic [ultradilute, potentiated] remedies are having effects on organisms – they cured my cat – one of the implications, it seems, is that the body has vibrational fields, patterned energy fields, on which these (vibrational, patterned) remedies can work. Many people, particularly those on the fringe of science, and beyond, have been saying this for years. But no one has demonstrated it in any convincing or replicable manner. This is where Prof. AbouHaidar’s discovery is so special. Finally we have a handle into this realm of vibration.”

Obviously, the author is caught in the “theory of vibrations” in his interpretations. This is a clear example of how a scientist slips and falls into “pseudoscience”. He understands he is moving into the realm of ‘fringe science’ and ‘beyond science’. And now he is trying to utilize “AbouHaidar’s discovery” to rationalize the speculations of ‘fringe science’ and ‘beyond science’, which “have been saying this for years”. He tries to utilize this unexplained phenomenon as a “handle into this realm of vibration”. The intention of the author is clear now. This shows how science can be used to rationalize ‘unscientific’ theories.

How does homeopathy work in practice? As a scientist, we would expect from the author an explanation that would fit to the existing scientific knowledge system available to modern biochemistry, molecular biology and medical science. But to our total dismay, he comes with totally unscientific and irrational concepts and arguments. He says:

“How does homeopathy work in practice? At its simplest level, let’s say you’re in an accident, traumatized, the body goes into a particular pattern of vibration, in this case a kind of ‘shock’, Often people seem to get stuck in these patterns. Tinctures made from the plant Arnica have a vibratory pattern that (we may imagine) closely resembles this vibratory pattern associated with traumatic shock. Empirically it has been observed, again and again, that the potentised remedy prepared from Arnica helps physically traumatised people to heal. So, it may be that the body becomes locked in a particular oscillatory pattern, and the remedy, the “similar”, helps to jog it free, to loosen that pattern’s hold on the body so the body can stop repetitively singing that song”

How is it? Is he talking science? Do these words reflect a scientific mind? We had many times heard this pseudo-scientific ‘theory of vibrations’ from so-called vitalists, classical homeopaths and metaphysical theoreticians. But it is a real pity to hear this from a reputed scientist. As a scientist, we would expect him to talk about the bio-chemical derangements caused by traumas, and how the constituent molecules of arnica tincture rectify these bio-molecular errors. How could the author reach such unscientific conclusions from the reported research findings? The researchers only observed the presence of some sort of ‘memory’ of DNA molecules in ultra-dilutions in water. They said nothing about the mechanism of this ‘memory’. Obviously, the author utilizes these findings to rationalize his ‘fringe science’ speculations. This is unfair and unethical as far as a scientist is concerned.

He continues his imaginative speculations further:

”A further implication of homeopathy is seen in the fact that the personality, the emotional make-up, the thought patterns, of patients are the most important guiding feature in deciding which remedy to use. The “mentals” are given more weight then the physical symptoms. The implication of this is that mind, that thought and emotion, are patterns”.

We expect to hear a scientist explain “thought and emotions” on the basis of neurochemistry, where as this ‘scientist’ is talking about ‘patterns’. Wonderful!.

His interpretation of ‘patterns’ in water formed by adding salt shows his total ignorance regarding the process of ‘hydration’ in aqueous solutions. Every science student knows that so-called patterning is nothing but supra-molecular clustering of water molecules through hydrogen bonding. I think he uses the terms like ‘patterns’ and vibrations’ to take this phenomenon into the realm of ‘fringe science’ which seems to be a subject very dear to him.

Instead of speculating over ‘patterns’ and ‘vibrations’, and discussing ‘fringe science’ and ‘beyond science’, this phenomenon could have been scientifically explained on the basis of “Molecular Imprinting”. Such an explanation would fit in to the existing scientific knowledge-system perfectly. More over, based on this concept, we can provide scientific explanation to the molecular mechanism of therapeutic action of potentized homeopathic medicines, fitting to modern biochemistry and molecular biology. Homeopathy could be dealt with not as a ‘fringe science” or “beyond science”. but as real science!

Let us listen to what the author says further on this subject:

“Come back to the one part salt in a hundred parts water. If we take this salt water and dissolve it again one part in a hundred in clear water, and shake it, it again patterns the water, but this time with some changes. Remember it’s at the 18th and 19th dilution that AbouHaidar’s target bound the probe (at least, that was the case in the first sample that MAME showed us). At the 15th, 16th, there was nothing. This suggests that we are seeing something similar to the interference phenomenon that occurs with harmonic overlays. This is a fairly well known phenomenon (e.g. “Poincare’s recurrence”, see below). However here because it’s a dilution procedure, the harmonics are going to include lower frequency multiples, “subharmonics”, of the original signal as well as the more usual higher frequency harmonics.

It is very funny to see how hastily the author jumps to his pre-determined conclusions such as ‘interference’ phenomenon and ‘frequency harmonics’, based simply on the observed phenomenon of ‘patterning’ of water in salt solutions. Before that he should have applied some thought regarding ‘hydrogen bonding’, hydration’ and ‘supra-molecular clustering’, and also the probability of ‘molecular imprinting’.

“Imagine a conjurer’s rope. Take a segment out of that magician’s rope – say one foot out of ten – and hold it taut between your hands, and twang it. Now (by magic) put it back in the original rope. The note, the vibration, in the small piece will pattern and inform the longer piece. The longer piece will now carry that information, but it will also, during the process, generate harmonics, multiples of that original note. But note, in the dilution process (which the homeopaths have traditionally called “potentiation”) it becomes intuitively apparent that we will be generating both harmonics andsubharmonics of the original pattern. And this explains one of the mysteries of homeopathy”

How can see declare that “this explains one of the mysteries of homeopathy”?

Obviously, he is overtly trying to ‘prove’ his concepts of ‘vibration theory’ in homeopathy utilizing the unexplained phenomenon observed by the research team..

“It is part of the traditional homeopathic wisdom that the higher potencies, the higher dilutions, are stronger and deeper acting than the lower potencies: that the mother tincture and the low potencies act superficially, at a surface level, at skin level, and at the physical level, while the high potencies act deeper and begin to effect emotions, thoughts, personality – and they are also, the high potencies, much stronger.”

Author tries to utilize the “traditional wisdom’ of homeopathy to rationalize his speculations. As a scientist, we expect from him rational explanations for those “traditional wisdom” on the basis of “scientific wisdom”. Not the other way.

“If I were going to treat you, say, with salt, sodium chloride (in Homeopathy we latinize it and call it Nat mur, short for Natrium muraticum). Now why would I treat you with Nat mur. Nat mur is one of the polycrests, which is to say it has power over an extremely broad range of symptoms, and with Nat mur, for sure, I would be guided in large part by personality and etiology (causation). Nat mur is seen in problems caused by grief where the person internalises. With that internalizing there’s a withholding and a holding. The person is likely to brood. “Attachment” is a key word with nat mur, and yet they don’t like to be consoled. Consolation will irritate them. The substance, salt, will cause (this pattern, this disposition) these problems, and it will also cure them. That’s why we call this type of medicine homeopathy: we treat like with like. This thought, that “like cures like” was Hahnemann’s great “law”. Now this, to me, is not intuitively apparent. But it is a piece of empiricism that was first recorded by Hippocrates, was reiterated by Paracelsus, and explored and developed into a fine art and science by Hahnemann at the end of the eighteenth and the beginning of the nineteenth century. Hahnemann experimented on himself. His first experiment was to take quinine. Quinine gave him ague-like fevers!”

As per the author this is the “scientific” explanation for the mechanism of homeopathic therapeutics. The wonder is that this ‘explanation’ comes from a “scientist”. According to him, “internalized grief” creates them “changes in pattern” in the “emotions” of an individual. “The substance, salt, will cause (this pattern, this disposition) these problems, and it will also cure them”. “That’s why we call this type of medicine homeopathy: we treat like with like”. How would this “explain the mysteries of homeopathy” as the author claim? To become a scientific explanation, he would have told us how “grief” creates the pathological disturbances in an individual, and what are the neuro-chemical errors happening at molecular level in various related biological pathways. We would also expect him to explain how sodium chloride creates similar biochemical changes individuals. If he wants to “explain the mysteries of homeopathy”, he should also explain what is the active principles in potentized sodium chloride, and how these active principles interact with the biochemical molecules and relieve the organism from the molecular errors caused by “grief”. That is the way a real scientist would talk about a science of therapeutics. Instead, the author talks about “patterns” created by “grief” and “patterns” created by “sodium chloride”. This is not the language of a scientist. We had already had this type of pseudoscientific “explanations’ ad nauseum fro the “gurus” and “masters” of “classical homeopathy”.

After making all these big noises about “explaining the mysteries” of homeopathy on the basis of concepts like “fringe science”, “beyond science”, “beyond substance”, “harmonics”, “resonance”, “vibrations” etc., it is quite wonderful how the author concludes”

“How do I know all this is what is going on? I don’t. I do know that homeopathy cured my cat. I know that MAME’s ultradilute DNA bound molecular DNA And then we have the well conducted clinical trials of Reilly published in Lancet that demonstrate beyond reasonable doubt that a phenomenon exists. Homeopathic remedies are reproducibly significantly more effective than placebo controls (Reilly 94). We know the phenomenon exists. What I’ve written here is my groping for an explanation.”

See his confession: “What i’ve written here is my groping for an explanation.”. That means, all through this article we were “groping” along with him!

Kindly read further:

“In May 1989 MAME submitted a paper on this ultradilute DNA phenomena to Nature. And Maddox, the editor, sat on it. In the summer of 1989 the University of Toronto opened a new botany building, and Prof. AbouHaidar moved his lab out of its old quarters. After the move and some initial difficulties for a short while the ultradilute experiment ran as before, though the pattern (18, 19, 25, 26) became more chaotic. But then shortly after the move, they lost the phenomenon! It no longer worked. They tried it a few times, and moved back to their mainstream work, genetic engineering, with the world not even ruffled.”

“It was not my impression that procedures, protocols, were clearly and precisely defined in AbouHaidar’s lab. (Elizabeth once characterized their work as “bucket chemistry”.) Nonetheless the phenomenon seemed to be robust up to the move, and for a short while after the move. As far as I am aware, apart from Elizabeth and my follow up in 1992/93, there has been no further work done with the phenomenon”

”The fact that when MAME moved labs the phenomenon vanished is itself fascinating”.

“So I urge anyone who has the opportunity to look for ultradilute activity, whether in dot-blots or in other assays, to do so. We stand on the threshold of a new science, a level of patterning in the natural world hitherto overlooked, and who can say where this knowledge might lead”

Dear friends, is this not the same proverbial situation we say “the mountain delivering a mouse”! The whole verbosity has finally faded into nothing!

According to Luc Montaigner, the ‘nanostructures’ formed in high dilutions are ‘mimics’ of original molecules. Scientifically, ‘molecular imprints’ are 3d structures with configurations just complementary to original molecules. If we consider original molecules as ‘keys’, montaigner consider ‘nanostructures’ as duplicate keys. According to my concept, ‘molecular imprints’ are ‘artificial key holes’ that could act as ‘artificial binding sites’ for original keys or keys similar to them. Molecular imprints bind to the pathogenic molecules due to complementary configuration, exactly like a key hole binds to a key. Molecular imprinting produces artificial key-holes, not duplicate keys. Once we understand this difference in perceptions, it would be easy for us to understand ‘similia similibus curentur’ scientifically.

Concept of ‘Molecular imprinting in Water’ involved in homeopathic potentization could have many unpredictable and unforeseen implications in the field of genetic engineering and gene therapy. Molecular imprints of genes or ‘DNA fragments’ could be utilized as templates for preparing ‘designer genes’ as per requirement in laboratories, that could be utilized for ‘genetic repairing’ protocols.

Extract the required genes or DNA fragments from healthy genomes and potentize them according to homeopathic procedures. These potencies would obviously contain ‘molecular imprints’ of DNA fragments used for potentization.

Add these potentized ‘DNA’ to a mixture of neucleotide primers and DNA polymerase enzymes involved in the biochemical process of DNA synthesis. ‘Molecular imprints’ can act as templates and selectively bind and hold the neucleotide primers in correct positions and sequences exactly similar to original DNA fragments used for imprinting. Polymerase enzymes will then link the individual neucleotides together to form DNA fragments exactly similar to original ones in terms of neucleotide structure and sequence.

This is a possibility I foresee when thinking about ‘molecular imprints’. Interested scientists are free to work upon this idea.

Since Luc Montaigner could not understand the scientific concept of ‘molecular imprinting’, he tried to explain the observed phenomenon using the concepts of ’emr resonance’. That only shows the limitation of his understanding.

Each and every particle in this universe are ‘vibrating’, or exist in constant motion. This ‘motion’ is the primary form of existence of matter. When we subject any object for any form of spectroscopic studies, there will be specific pattern of light rays, depending up on absorption, reflection and refraction which indicates molecular level organization. When we subject potentized drugs for spectrosopy, the light patterns are found to be different from those of unpotentized water-alcohol mixture. That only indicates the presence of ‘supramolecular clusters’ formed by potentization. DNA will have specific spectum, molecular imprints of DNA will also have spectific spectrum. We can utilize spectroscopic studies of potentized drugs to sturdy the presence of molecular imprints in our potentized drugs.

‘Supra molecular nanostructures’ is an important topic of study with implications in in areas of nanotechnology, supramolecular chemistry, molecular imprinting in polymers etc. I was trying to explain homeopathic potentization from this perspective.

Polymer-like supramolecular behavior of water and its capacity to form ‘supramolecular nanostructures’ through hydrogen bonding make water an appropriate medium for molecular imprinting. Through the process of molecular imprinting involved in potentization, three dimensional configuration of individual drug molecules are imprinted into these supramolecular nanostructures of water as ‘nanocavities’, which can act as ‘artificial key-holes’ or ‘binding sites’ for the drug molecules as well as pathogenic molecules having simialar functional groups. This is the scientific explanation I provide for homeopathic potentization.

If a drug substance could produce some groups of symptoms that are similar to those expressed in a disease condition, what does it mean?

It means the drug substance and disease-causing subatance could produce similar errors in siimilar biochemical pathways in the organism.

It means, the drug substance contained some chemical molecules having functional groups similar to those contained in disease causing substance, so that they could bind to similar biomolecular targets in the organism and produce similar molecular inhibitions.

In the language of modern biochemistry, it could be said that the chemical molecules in disease causing substance and the chemical molecules contained in the drug substance have a COMPETITIVE RELATIONSHIP, and they compete each other in binding to similar biological targets.

Both of them will have a COMPETITIVE relationship also with the natural ligands of those biological target molecules.

This phenomenon of COMPETITIVE RELATIONSHIP in biochemical interactions play a big role in molecular processes involved in DISEASE processes, DRUG toxicity as well as CURE.

Modern drug designing techniques are based on the study of this phenomenon of COMPETITIVE RELATIONSHIP.

What HOMEOPATHY calls SIMILIMUM is actually a drug substance that contains some chemical molecules that can COMPETITIVE with the disease causing molecules.

Since molecular inhibitions are expressed through SYMPTOMS, homeopathy identifies this relationship by observing the SIMILARITY OF SYMPTOMS produced in human body by DISEASE as well as those produced by what is called DRUG PROVING.

When drugs are potentized, the individual chemical molecules contained in the the drug substance undergo a peculiar supra-molecular process known as MOLECULAR IMPRINTING in modern polymer chemistry.

Through host-guest interactions between water-alcohol supra-molecular matrix and individual drug molecules, three dimensional nanocavities are formed, having conformations just complementary to the drug molecules that work as templates in this process.

These nanocavities are called MOLECULAR IMPRINTS. These molecular imprints can act as ARTIFICIAL BINDING POCKETS for disease causing molecules having complementary RELATIONSHIP.

As such, molecular imprints can bind to and deactivate the disease causing molecules, thereby removing molecular inhibitions of biological molecules. This is CURE.

It is obvious that molecular imprints of similar molecules will have complementary affinity towards all chemical molecules having similar functional groups, or which have COMPETITIVE RELATIONSHIP to each other.

SIMILIMUM, DRUG PROVING and SIMILIA SIMILIBUS CURENTUR are explained above very clearly, in a way fitting to modern scientific knowledge system.

I am not responsible if you could not understand, or if you hesitate to understand!

Acetylcholine is an organic chemical that functions in the brain and body of many types of animals and humans as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells, such as neurons, muscle cells and gland cells.

Atropine is an alkaloid contained in plants such as belladonna. Since Atropine has some functional groups similar to that of acetylcholine, it competes with acetylcholine in binding to the acetylcholine receptors and inhibits their actions.

During drug proving of belladonna tincture, Atropine molecules contained in it competitively bind to acetylcholine receptors and inhibit their actions. These inhibition of acetylcholine receptors result in a lot of deviations in various bio-chemical pathways involved, which is expressed through diverse groups of subjective and objective symptoms we see in the materia medica of BELLADONNA.

Post-avogadro dilutions of BELLADONNA contains MOLECULAR IMPRINTS of ATROPINE, along with those of many other chemical molecules contained in it.

When a person in disease shows symptoms of BELLADONNA, it means the pathogenic molecules that cause particular disease condition contain some chemical molecules that bind to and inhibit the acetylcholine receptors. Molecular imprints of atropine will have conformational affinity to those pathogenic molecules, by which they can bind the pathogenic molecules and deactivate them. That is exact biological mechanism involved in the therapeutic actions of post-avogadro dilutions of BELLADONNA.

ATROPINE is not the only chemical molecule contained in belladonna, and as such, this explanation is only a partial study of BELLADONNA.

When you understand the science and logic involved in MIT, and start perceiving potentized drugs in terms of diverse types of ‘molecular imprints’ as the ‘active principles’ they contain, you will realize that all controversies over ‘single/multiple’ drug issue leveled against MIT become totally irrelevant.

According to MIT view, ‘similimum’ essentially means a drug substance that can provide the specific molecular imprints required to remove the particular molecular errors that caused the particular disease condition in the particular patient. Whatever be the ‘method’ by which the drug is selected, similimum is a similimum if it serves the purpose of curing the patient when administered in potentized form.

Since ‘multiple’ molecular errors exist in any patient in a particular point of time, expressed through ‘multiple’ groups of symptoms, he will inevitably need ‘multiple’ molecular imprints to remove them. If potentized form of a ‘single’ medicinal substance can provide all those ‘multiple’ molecular imprints, that ‘single’ drug substance will be enough. If we could not find a ‘single’ drug substance that contain ‘all’ the ‘multiple’ molecular imprints required by the patient as indicated by the ‘symptom groups’, we will have to include ‘multiple’ drug substances in our prescription. It is the constituent molecular imprints contained in our particular prescription that matter.

Important point is, we have to ensure that our prescription supplies all the diverse types of molecular imprints required for deactivating all the diverse types of pathogenic molecules existing in the patient, as indicated by the diverse groups of subjective and objective symptoms expressed by him. If we could find a single drug preparation that could supply all the molecular imprints required by the patient I am dealing with, we can use that single drug preparation only. If we do not find such a single drug, we have to include as many number of drug preparations as required, in order to provide all the molecular imprints needed to remove all the molecular errors in the patient.

‘Single/multiple’ drug controversy never bothers one who understands this scientific approach proposed by MIT, as we start thinking in terms of molecular imprints- not in terms of drug names. Actually, a drug becomes ‘single’, if it contains ‘single’ type of molecular imprints only. IF a drug contains more than one type of molecular imprints, it is a compound drug, even if it is known by a ‘single’ drug name, prepared from a ‘single’ source material, kept in a ‘single’ bottle, consumed as a ‘single’ unit for ‘drug proving’, or considered by ‘masters’ as ‘single’ drug.

When we consume a complex drug substance in crude form, it is absorbed into the blood as various individual chemical molecules contained in it. It is these individual chemical molecules that interact with various biological molecules. Different molecules act up on different biological targets according to the molecular affinities of their functional groups. Biological molecules are inhibited, resulting in errors in the biochemical pathways mediated by those biological molecules. Such molecular level errors in biological processes cascades into a series of molecular errors, which are expressed through various groups of subjective and objective symptoms.

It is obvious that what we consider as the symptoms of that drug substance are actually the sum total of different symptom groups, representing entirely different molecular errors produced in entirely different biological molecules, by the actions of entirely different chemical molecules contained in the crude drug.

We have to remember, there is no such a thing called nux vomica molecule or pulsatilla molecule- only individual chemical molecules contained in nux vomica or pulsatilla tinctures. Each constituent molecule has its own specific chemical structure and properties. They act on different biological targets by their chemical properties.

Each individual chemical molecule contained in a complex crude drug substance acts as an individual drug. That means, nux vomica or pulsatilla are not single drugs as we are taught, but compound drugs. Classical homeopaths may find it difficult to accept this fact, as it contradicts with their beliefs as well as the lessons they are taught. But it is the scientific fact.

From scientific point of view of pharmaceutical chemistry, a drug is a biologically active unit contained in a substance used as therapeutic agent. It is the structure and properties of that chemical molecule that decides its medicinal properties and therapeutic actions. if such as substance contains only one type of biologically active unit, it is a single drug. If it contains different types of biologically active units, it is a compound drug. It is obvious that most of the drugs we use in homeopathy – especially drugs of biological origin and complex minerals- contain diverse types of biologically active units, and hence they cannot be considered single drugs.

Molecular imprinting happens as individual molecules, and as such, potentized drugs prepared from a single drug substance will contain diverse types of molecular imprints representing the diverse types of individual constituent molecules contained in the substance. Those molecular imprints also act as individual units when applied in the organism. Hence, potentized drugs prepared by using a complex, seemingly single drug substance is actually a compound drug, containing diverse types of biologically active units, or ‘molecular imprints’.

‘Combinations’ of potentized drugs:

A serious objection against MIT from the side of classical homeopaths is regarding ‘mixing’ or ‘combinations’ of potentized drugs. On the other hand, MIT says that it is permissible for to use combinations of ‘molecular imprinted’ forms (potencies above Avogadro limit- 12c and onwards) of two or more homeopathic drugs selected on the basis of analysis of totality of symptoms, miasmatic study and biochemical evaluation of the individual patient.

MIT view is that it is effective as palliatives to use ‘disease-specific’ combinations of ‘molecular imprinted’ forms (potencies above Avogadro limit- 12c and onwards) of two or more homeopathic drugs selected on the basis of common symptoms and biochemical evaluations of specific diseases. But such ‘disease-specific’ combinations will not offer ‘total cure’ for patients, without incorporating drugs selected on the basis of symptoms also. This approach also is very close to the method of ‘banerji protocols’ that makes ‘specific’ prescriptions based on ‘disease diagnosis’ as well as symptomatology..

I am talking on the basis of my concepts of ‘molecular imprinting’ involved in potentization. I perceive all crude drugs as combinations of diverse types of constituent drug molecules. I perceive even the so called potentized ‘single’ drug as combinations of diverse types of individual drug molecules contained in the drug substance used for potentization.

My stand on this issue is based on my understanding of diseases as multitudes of pathological derangement in the organism, caused by diverse of types of molecular inhibitions caused by different types of pathogenic agents, and therapeutics involves the removal of those inhibitions using appropriate molecular imprints.

I am talking on the basis of my understanding of ‘similia similibus curentur’ as: “pathological molecular inhibitions caused by specific pathogenic molecules and expressed through a certain group of subjective and objective symptoms, could be removed by applying ‘molecular imprints’ of drug molecules that could create similar molecular inhibitions and symptoms in a healthy organism when applied in crude form.

That makes the difference between my views and classical homeopathy. I know, homeopaths trained and experienced in classical homeopathy cannot agree with my views on this topic.

Government of India has finally given permission to conduct trials in prevention and treatment of COVID 19 using homeopathy medicines. Only very rare homeopaths who have access to institutions with facilities for quatentine and covid management will be able to utilize this opportunity. Since I have no such access, I am unfortunately compelled to stay back.

Those homeopaths who are fortunate to conduct trials, should be very careful. You will have to do this trial in a very inimical environment. There will be ethical committees, monitoring committees, evaluation committees etc in such institutions to oversee your work, which will be constituted by modern medical doctors mostly determined to prove homeopathy ineffective. All the paramedical staff and resident doctors will not be under your control. You can imagine what would be the outcome in such situations.

Remember, you are bound to fail, if you think you can convince the skeptics regarding the efficacy of potentized homeopathic drugs by conducting conventional types of ‘clinical trials’ or RCTs as they demand for.

You can never expect ‘individual-based’ homeopathic drugs to be proved using the protocols of testing drugs in ‘disease-based’ modern medicine. Asking to ‘prove’ homeopathic drugs using protocols of allopathic drug trials is like trying to measure ‘length’ using units of ‘mass’.

Allopathic methods of ‘drug trials’ are applicable to ‘molecular forms’ of drugs only. But potentized homeopathic drugs, different from allopathic drugs, contain only ‘molecular imprints’, which can act only up on pathogenic molecules having specific conformational affinity. That means, potentized drugs can act only if indicated by similarity of symptoms.

You cannot ignore this peculiarity of homeopathy in matters of active principles as well as mechanism of drug actions while designing ‘drug trials’ for homeopathy.

In homeopathy, you cannot ‘verify’ action of a particular drug on a particular disease- you have to ‘verify’ action of ‘indicated drugs’ up on indicated individual patients, since different people with same disease may need different drugs.

Same time, disease-specific combinations of post-avogadro dilutions could be subjected to Random Controlled Trials in the same way as allopathic drugs. This is the most effective way to prove that potentized homeopathy drugs are not placebo, fraud, or “mere water”, but they really work.

As far as skeptics as well as homeopaths hesitate to accept this peculiarity of potentized homeopathic drugs and agree to design the ‘trials’ of disease-specific combinations of post-avogadro dilutions, there is no way to convince the scientists that ‘homeopathy’ works’.

I would suggest you to prepare your own combinations for Covid-19 trial, incorporating ALL the drugs you think indicated for that disease, and conduct trials using that combination.

COVID 19 trials pose both an opportunity and a challenge for homeopathy. If we fail in this challenge – remember, people around you want you to fail- it will be very difficult for us to come back.

Ensure success for homeopathy in this trial. Cast away your theoretical prejudices. Don’t hesitate to use multiple remedies and combinations. Don’t hesitate to repeat doses in enough quantities and frequencies. Use 30c potencies only to ensure perfect result.

I WANT TO REPEAT: WE CAN SUCCESSFULLY PROVE THE EFFECTIVENESS OF HOMEOPATHY THROUGH RANDOM CONTROLLED TRIALS ONLY BY USING DISEASE-SPECIFIC COMBINATIONS OF POST-AVOGADRO DILUTIONS.

This is an earnest appeal from an old man who has been loving, living, learning, experimenting and researching homeopathy for around last FIFTY YEARS!

It is a fact that homeopaths around the world produce thousands of genuine homeopathic cures every day by applying post-avogadro diluted homeopathic drugs.

Number of cures produced by homeopaths using mother tinctures, low potencies, triturations and other MOLECULAR forms of drugs, and claimed to be “homeopathic” cures, are very much higher, even though they cannot be considered as genuine homeopathic cures.

“SUCCESS STORIES” you produce by using MOTHER TINCTURES, LOW POTENCIES, or TRITURATIONS cannot be called HOMEOPATHIC CURES.

You have not prescribed those drugs as SIMILIMUM, by using TOTALITY OF SYMPTOMS, and they do not act upon our body by a BIOLOGICAL MECHANISM that is really HOMEOPATHIC.

What you have done is no way different from AYURVEDA or ALLOPATHY!

Genuine HOMEOPATHIC cure will happen only when you use post-avogadro diluted drugs which do not contain DRUG MOLECULES, but MOLECULAR IMPRINTS only!

Most homeopaths do not mention the names of mother tinctures, low potencies and triturations they have used for producing some “results”, while preparing SUCCESS STORIES for publishing, may be due to this prick of conscience! They give names of HIGH POTENCIES only- that too, SINGLE DRUG and SINGLE dose!

Many homeopaths believe that publishing the case records of these cured cases, appended with lab reports are enough PROOF for the SCIENTIFIC VALIDITY of homeopathic theoretical system.

Homeopaths should understand that these “success stories”, or so called “anecdotes”, are never accepted as valid proof for anything, as per SCIENTIFIC METHOD.

To be accepted as scientific proof, we have to produce repeatable results of homeopathic cures through well monitored double blind random controlled trials. In the absence of such random controlled trials, nobody except homeopaths are going to take these “success stories” seriously.

Do you think your “success stories” validates every thing written in organon, and taught as FUNDAMENTAL PRINCIPLES of HOMEOPATHY, such as the theory of VITAL FORCE and DYNAMIC ENERGY?

Do you think your “success stories” validates you beliefs such as “matter is converted into energy” during potentization, and that “atomic energy” is preserved in the potentizing drugs we carry in sugar pills and glass bottles?

Do you think your “success stories” have proved your BELEIF that bacteria or viruses do not cause diseases, but diseases are caused by deficiencies of VITAL FORCE?

Do you think your “success stories” have proved your unscientific notions of IMMATERIAL life, IMMATERIAL disease, IMMATERIAL cure and IMMATERIAL drugs?

Even if these “success stories” are considered genuine, only thing they actually prove even to a SUPPORTER of homeopathy is that “homeopathy works”! They do not provide any proof for scientific validity of the theoretical system of homeopathy.

Success stories do not prove HOW homeopathy works. For that, we should formulate scientifically viable hypotheses, evolve PREDICTIONS therefrom , conduct experiments, and prove the hypothesis according to SCIENTIFIC METHOD.

In short, as per SCIENTIFIC METHOD, we need to provide sufficient data to prove HOMEOPATHY WORKS, through well organized and well supervised Random Controlled Trials (RCT), if we really want homeopathy to be recognized as a THERAPEUTIC METHOD by scientific community.

We need to explain what is the material process involved in POTENTIZATION, what are the ACTIVE PRINCIPLES of post-avogadro homeopathic dilutions, and what is the BIOLOGICAL MECHANISM of their therapeutic actions, prove those explanations according to SCIENTIFIC METHOD, if we really want homeopathy to be recognised as a MEDICAL SCIENCE by scientific community.

Concept of combining potentized drugs evolves from my understanding that potentization involves a process of ‘molecular imprinting’, and individual constituent molecules of drugs are ‘imprinted’ in their individual capacities.

According to this understanding, even a drug we consider ‘single’ is in fact a mixture of different types of  ‘molecular imprints’ of diverse constituent drug molecules, and they exist without interacting with each other.

According to this view, even if we mix two or more potentized drugs together, the constituent ‘molecular imprints’ will not interact each other, and will act up on the appropriate molecular targets in their individual capacities.

For the last few years I was experimenting on this issue, and I have found it totally harmless and very effective to combine potentized drugs above 30c, selected on the basis of  constitutional as well as particular ‘symptom complexes’.

Hahnemann was talking about SINGLE drug on the basis of scientific knowledge available to him during his period 250 years ago.

He had no idea about the molecular level structure of drug substances, or their molecular level interactions with biological molecules. He had no idea about the molecular level pathology and molecular inhibitions undelying diseases. He considered drugs as ‘single’ substance, and diseases as ‘singular’ entities.

For him, NUX was a ‘single’ substance, whereas we now know NUX tincture is a mixture of hundreds of types of alkaloids, gycosides and other phytochemicals, which act upon our body on the basis of their molecular structure and chemical properties.

All those noises made by CLASSICAL homeopaths over SINGLE DRUG/ MULTIPLE DRUGS issue actually come from their lack scientific understanding of homeopathy.

When a drug substance containing different types of chemical molecules is subjected to potentization, each chemical molecule undergoes  molecular imprinting as individual units.

As such, any potentized drug will be a combination of diverse types of molecular imprints representing diverse types of constituent chemical molecules, which can act upon the pathogenic molecules as individual units, in capacity of their individual conformational properties.

When we combine two or more potentized drugs together, all the diverse types of individual molecular imprints contained in those different drugs will exist in that combination as individual units, and act up on pathogenic molecules by their individual conformational properties.

Obviously, a combination of of different potentized drugs will be no way different from a potentized single drug that contains diverse types of chemical molecules.

Molecular imprints act upon pathogenic molecules act as individual units, whether they come from single drug substance or multiple drug substances.

All controversies over single drug/ multiple drugs become totally irrelevant once you realise this scientific truth. But you can understand this truth only if you have a scientific temper, and you are capable of thinking beyond the lessons you learned from organon and your unscientific teachers!

Once homeopathic community could realize and accept the great truth that disease-specific COMBINATIONS of homeopathic drugs in 30c potencies are many many times more effective and safer than so-called SINGLE drugs, homeopathy will be on the top of all medical systems in this world! There will not be any disease that could not be practically cured by using rationally formulated appropriate combinations. All homeopaths should be taught the art and science of preparing and using their own formulations

Whether for prophylactic or curative purpose, you cannot expect a so-called SINGLE homeopathic post-avogadro diluted drug to work as a specific for a DISEASE in a community as a whole.

To be successful, you need to use a well-formulated disease-specific combination of MULTIPLE drugs in post-avogadro dilutions for that purpose.

It is based on this rational idea that we have formulated more than 350 disease-specific post-avogadro MIT FORMULATIONS which are used by homeopaths around the world successfully.

Once you understand MIT explanations of scientific homeopathy, and start perceiving potentized drugs in terms of diverse types of ‘molecular imprints’ as the ‘active principles’ they contain, you will realize that all controversies over ‘single/multiple’ drug  issue  become totally irrelevant.

According to MIT view, ‘similimum’ essentially means a drug substance that can provide the specific molecular imprints required to remove the particular molecular errors that caused the particular disease condition in the particular patient. Whatever be the ‘method’ by which the drug is selected, similimum is a similimum if it serves the purpose of curing the patient when administered in potentized form.

Since ‘multiple’ molecular errors exist in any patient in a particular point of time, expressed through ‘multiple’ groups of symptoms, he will inevitably need ‘multiple’ molecular imprints to remove them. If potentized form of a ‘single’ medicinal substance can provide all those ‘multiple’ molecular imprints, that ‘single’ drug substance will be enough. If we could not find a ‘single’ drug substance that contain ‘all’ the ‘multiple’ molecular imprints required by the patient as indicated by the ‘symptom groups’, we will have to include ‘multiple’ drug substances in our prescription. It is the constituent molecular imprints contained in our particular prescription that matter.

Important point is, we have to ensure that our prescription supplies all the diverse types of molecular imprints required for deactivating all the diverse types of pathogenic molecules existing in the patient, as indicated by the diverse groups of subjective and objective symptoms expressed by him. If we could find a single drug preparation that could supply all the molecular imprints required by the patient I am dealing with, we can use that single drug preparation only. If we do not find such a single drug, we have to include as many number of drug preparations as required, in order to provide all the molecular imprints needed to remove all the molecular errors in the patient.

‘Single/multiple’ drug controversy never bothers one who understands this scientific approach proposed by MIT, as we start thinking in terms of molecular imprints- not in terms of drug names. Actually, a drug becomes ‘single’,  if it contains ‘single’ type of molecular imprints only. IF a drug contains more than one type of molecular imprints,  it is a compound drug, even if it is known by a ‘single’ drug name, prepared from a ‘single’ source material, kept in a ‘single’ bottle, consumed as a ‘single’ unit for ‘drug proving’, or considered by ‘masters’ as ‘single’ drug.

When we consume a complex drug substance in crude form, it is absorbed into the blood as various individual chemical molecules contained in it. It is these individual chemical molecules that interact with various biological molecules. Different molecules act up on different biological targets according to the molecular affinities of their functional groups. Biological molecules are inhibited, resulting in errors in the biochemical pathways mediated by those biological molecules. Such molecular level errors in biological processes cascades into a series of molecular errors, which are expressed through various groups of subjective and objective symptoms.

It is obvious that what we consider as the symptoms of that drug substance  are actually the sum total of different symptom groups, representing entirely different molecular errors produced in entirely different biological molecules, by the actions of entirely different chemical molecules contained in the crude drug.

We have to remember, there is no such a thing called nux vomica molecule or pulsatilla molecule- only individual chemical molecules contained in nux vomica or pulsatilla tinctures. Each constituent molecule has its own specific chemical structure and properties. They act on different biological targets by their chemical properties.

Each individual chemical molecule contained in a complex crude drug substance acts as an individual drug. That means, nux vomica or pulsatilla are not single drugs as we are taught, but  compound drugs.      Classical homeopaths may find it difficult to accept this fact, as it contradicts with their beliefs as well as the lessons they are taught. But it is the scientific fact.

From scientific point of view of pharmaceutical chemistry, a drug is a biologically active unit contained in a substance used as therapeutic agent. It is the structure and properties of that chemical molecule that decides its medicinal properties and therapeutic actions. if such as substance contains only one type of biologically active unit, it is a single drug. If it contains different types of biologically active units, it is a compound drug.  It is obvious that most of the drugs we use in homeopathy – especially drugs of biological origin and complex minerals- contain diverse types of biologically active units, and hence they cannot be considered single drugs.

Molecular imprinting happens as individual molecules, and as such, potentized drugs prepared from a single drug substance will contain diverse types of molecular imprints representing the diverse types of individual constituent molecules contained in the substance. Those molecular imprints also act as individual units when applied in the organism. Hence, potentized drugs prepared by using a complex, seemingly single drug substance is actually a compound drug, containing diverse types of biologically active units, or  ‘molecular imprints’.

SIMILIMUM is the most essential and fundamental concept that characterize homeopathy as a therapeutic method. It originates from the word SIMILAR. Actually, the HOMEOPATHY means SIMILAR  “pathos” or “suffering”- similar “disease”. SIMILIMUM means a drug substance that can produce a “suffering” or “disease” in human body that is SIMILAR to the disease we want to treat.

Homeopathy is basically a method of curing diseases using drug substances that can produce “suffering” in human body that are similar to the “suffering” experienced in that disease condition. 

What does it mean if a substance is capable of producing “suffering” in a human body that are similar to the “suffering” in a disease condition?

It means, the drug substance is capable of producing some pathological molecular inhibitions in human body that are SIMILAR to the molecular inhibitions that caused the original disease condition.

To be capable of producing SIMILAR molecular inhibitions, the drug substance should contain some chemical molecules that can bind to the same biological targets which have been inhibited by the disease causing pathogenic molecules. In order to be capable of binding to the same biological targets, the drug molecules and pathogenic molecules should carry SIMILAR functional groups having SIMILAR molecular conformations.

It is well known in modern BIOCHEMISTRY that chemical molecules having similar functional groups will exhibit a peculiar kind of COMPETITIVE RELATIONSHIP in between them for binding to a perticular biological target molecule. This COMPETITIVE RELATIONSHIP between different chemical having SIMILARITY of functional group conformations plays a big role the molecular dynamics of disease and therapeutics in modern pharmacology.

It is very much obvious that within the historical  limitations of scientific knowledge available to him, the great genius of Dr Samuel Hahnemann was observing this natural phenomenon of COMPETITIVE RELATIONSHIP between chemical molecules in binding to the target molecules and producing DISEASE as well as CURE.

Hahnemann utilized this observation as the basis of a new therapeutic method named HOMEOPATHY, with the therapeutic principle SIMILIA SIMILIBUS CURENTUR.

Can ANYBODY with unbiased rational mind still say homeopathy is UNSCIENTIFIC?

APRIL 10 should be a day of introspection for homeopaths. A rational, truthful, unprejudiced and scientific introspection.

Did we actually do justice to Samuel Hahnemann?

Did we,  his “followers” and “disciples”, actually do anything all these two hundred years to take forward and update his contributions, which were historically limited by the primitive scientific knowledge environment available to  him during his period?

Did we do anything seriously to dig out the precious gems of truthful observations hidden in his voluminous works, such as SIMILIA SIMILIBUS CURENTUR and POTENTIZATION, polish them using scientific methods, and present them to the modern scientific community so as to get the recognition and place he deserved in the knowledge history?

Is it not really amazing that during a period when modern biochemistry did not even emerge, hahnemann could observe the phenomenon of “competitive relationship of similar chemical molecules in  binding to the biological targets”, and develop it into the foundation of a therapeutic principle he called SIMILIA SIMILIBUS CURENTUR?

It is equally amazing that Hahnemann could utilize the natural phenomenon of MOLECULAR IMPRINTING happening in the process of post-avogadro dilutions he called POTENTIZATION, and develop it into a technology of preparing a new class of therapeutic agents, during a period when modern polymer technology or supra-molecular chemistry did not even emerge?

What his “blind” followers did all these years was to make him an idol of worship, without recognizing the great scientist in him. They converted his words into mere dogmas, to be learned and recited just like religious preachings!

Hahnemann failed to get the due respect and recognition in the history of medical science, only due to his unscientific and shortsighted followers and disciples who made his ideas and its practices more and more superstitious, spiritualistic and irrational.

Today should be a day for introspection, dear friends!

I know most homeopaths cannot tolerate what I am saying below, especially if they are not already familiar with the MIT explanations regarding potentization and biological mechanism of homeopathic cure.

Use of pre-prepared ‘disease-specific’ combinations of potentized drugs added with custom-made ‘patient-specific’ constitutional similimum will make the practice of homeopathy more simple and effective, and will bring down the rate of clinical failures to the lowest minimum level, even for most inexperienced beginners.

For example, we can make an effective anti-febrile formulation by working out with ‘symptom-complexes’ expressed in various types of fevers and finding their similimum separately, and then combining them together in a single container.

Selected drugs should be used preferably in 12c or 30c potencies, and should be procured from most reliable manufacturers.

We can add some specifics, sarcodes and nosodes into this combination, selected using our knowledge of biochemistry regarding the molecular level processes involved in producing a pathological condition of fever.

We can keep this preparation as a disease-specific ANTIFEBRILE stock medicine.

In most cases of fevers, a few drops this formulation put on the tongue of the patient will cure the fever instantly. A few more doses may be repeated at intervals, to ensure the fever is completely gone.

If the fever reccurres in spite of repetitions, or in order to avoid the chances of such reccurences, we can work out the constitutional similimum of the individual patient by considering his mental symptoms and physical generals, and add it also to the stock medicine when dispensing. Such a prescription will be ‘disease-specific’ as well as ‘patient-specific’, and it will be amost perfect prescription that will ensure 100%cure.

In this way, we can prepare stock formulations for all common disease conditions, such as headache, diarrhoea, vomiting, cough, asthma, hypertension, diabetes, lipidemia, rheumatism, urinary infection, colic, gall stones, or anything like that.

When a patient comes, work out his constitutional similimum, add it also to a small quantity of stock formulation, and give to the patient without any theoretical inhibitions in your mind. And see the marvel happening!

Please do not come to argue by quoting aphorisms. Try to understand the scientific logic and rationale behind my suggestion. I have explained it in detail in my book REDEFINING HOMEOPATHY, as will as my blog. Try to read. If not interested, kindly excuse me!

‘Palliation’ in medical context actually means ‘temporary relief’ or removal of some of the most disturbing symptoms in the patient using some drugs, without curing the underlying disease.

Allopathic palliative treatment involves the use of certain chemical drugs in molecular forms. They are used to reduce the sufferings, without any hope of cure by that prescription. In some situations, palliative approach is used to reduce sufferings until correct diagnosis and treatment protocol is finalized. Since chemical molecules can interact with biological molecules, allopathic palliation may produce harmful effects. In fact, allopathic palliation makes the case more complicated, and hence it is normally used as a temporary relief measure only in cases that are considered to be incurable.

Some homeopaths even use allopathic drugs under the label of ‘palliative prescription’. Some others use large quantities of mother tinctures even without any homeopathic indications. Even if you call it “homeopathic” drugs, removal of symptoms using molecular forms of drugs such as mother tinctures, low potency drugs or so-called biochemic salts are actually not at all different from allopathic palliation. Such palliation using mother tinctures and low potency drugs may also harm the patient, or hinder the curative process similar to allopathic palliation, since those drugs in molecular forms are no way different from allopathic drugs regarding their biological mechanism of action. Use of such drugs also may produce harmful effects or make the case more complicated, since the chemical molecules contained in them can produce molecular inhibitions in unexpected biological targets.

To be really “homeopathic” in its real sense, palliation should be produced by applying drugs potentized above 12c, which contain only molecular imprints.

Since molecular imprints cannot interact with biological molecules, and can interact only with pathogenic molecules, homeopathic palliation cannot produce any harmful effects. Potentized drugs act only if there are some molecular inhibitions that could be removed by the molecular imprints contained in the particular potentized drug. Symptoms could be removed using potentized drugs only if the underlying molecular errors are removed at least partially.

Each group of symptoms expressed by the patient points to a particular pathological error in a particular biological pathway caused by inhibition of a particular biomolecule by binding of a particular pathogenic molecule. We can remove symptoms only if the drug we apply contains appropriate molecular imprints that can remove at least some of the molecular errors in the patient.

Homeopathic palliation using potentized drugs never hinders the cure. In its exact meaning, it is actually not palliation, but partial cure. We can convert this partial cure into complete cure by supplying the additional molecular imprints that were missing in the earlier prescription, by new drugs given as complementary prescriptions.

Lesson for homeopaths: If you want to offer palliation to a patient, try to produce it it by administering potentized drugs only. They should be similimum selected on the basis of most disturbing groups of symptoms expressed by the patient. Even if such a partial similimum will not offer complete cure, it never hinders the chances of getting complete cure later through additional homeopathic prescriptions.

Never use mother tincture, allopathic drugs, or any drug in molecular form in the name of palliation. Such practice will complicate the case, and hinder the curative process.

Some friends ask me to explain my views on posology of molecular imprinted drugs.

While trying to answer this question, we have to remember that the issue of posology has to consider three aspects:

1. Minimum quantity of drug needed to be given per dose to produce a therapeutic action,

2. Maximum quantity of the drug that could be administered as a dose to ensure that there is no bad effects,

3. Most appropriate frequency of administration or repetition of doses.

Regarding the first question, it is difficult to define exactly what is the minimum quantity of molecular imprinted drug to produce therapeutic effect. To do that, we have to know the exact number of biological molecules affected, as well as the exact number of molecular imprints contained in a given measure molecular imprinted drugs. Both are impossible in the present stage of technology available to us.

Size of a molecular imprint will vary depending upon the size of drug molecule used for molecular imprinting, which in turn determine the number of molecular imprints contained. It is not practical to count these numbers. On the other side, it is also not practical to determine the biological molecules inhibited. Only thing we can do is to determine the minimum dose of drugs through experimenting in real situations.

We should remember, according to avogadro, number of water molecules in 18ml of water will be 6.022140857 × 1023. From this, we can calculate the number of water molecules in 1ml. 1ml contains 15 drops. It is not difficult to understand that the number of water molecules contained in even 1 drop of water so huge for calculation. Same way we can calculate the number of alcohol molecules in 1 drop of alcohol.

Overall, it is obvious that one drop or even a fraction of molecular imprinted drugs will contain millions of molecular imprints. As such, we need not worry much about the minimum quantity of molecular imprinted drugs to be used for therapeutic purpose. It may be as small as we can handle. Normally I prefer one drop for one dose.

Regarding the second question, MIT says that molecular imprints cannot do any harm upon biological system. As such, we need not worry at all about the maximum quantity administered as a dose.

Regarding third question, we have to be aware of the possible changes molecular imprints may undergo once introduced in the body.

Molecular imprints could be antidoted by any chemical molecule having conformations affinity. As such, the drugs we consume may get easily antidoted and deactivated by various chemical molecules entering our body through food, inhalation, drinks and many other ways.

Hence we have to repeat the doses in frequent intervals to ensure adequate quantity of molecular imprints to ensure full and lasting therapeutic effect.

MILK SUGAR or LACTOSE is the most prominent substance currently used as homeopathic drug dispensing vehicles. It is used in the form of POWDERS or TABLETS of different sizes, which are medicated by adding potentized homeopathic drugs.

I think a detailed study of LACTOSE is essential to decide whether it is an ideal dispensing vehicle. Theoretically, an ideal DISPENSING VEHICLE should be a substance with following properties:

1. IT SHOULD NOT BE A DRUG SUBSTANCE BY ITSELF,

2. IT SHOULD BE CHEMICALLY INERT,

3. IT SHOULD NOT INTERACTING WITH DRUGS,

4. IT SHOULD BE INDIGESTIBLE,

6. IT SHOULD NOT BE NOT ABSORBED INTO THE BODY,

7. IT SHOULD NOT HAVE ANY LONG TERM OR SHORT TERM TOXIC EFFECTS,

8. IT SHOULD NOT HAVE ANY NUTRITIONAL OR CALORIC VALUE

I am suggesting homeopaths to go through the complete MATERIA MEDICA of LACTOSE from Clarke’s Materia Medica.

Please read symptomatology carefully, keeping in mind that all those symptoms represent the molecular errors produced by lactose in healthy individuals. Then you decide yourself whether MILK SUGAR we regularly feed our patients is an ideal DISPENSING VEHICLE.

Lactose is a disaccharide. It is a sugar composed of galactose and glucose. Lactose makes up around 2–8% of milk (by weight). The compound is a white, water-soluble, non-hygroscopic solid with a mildly sweet taste. It is used in the food industry.

Lactose is hydrolysed to glucose and galactose, isomerised in alkaline solution to lactulose, and catalytically hydrogenated to the corresponding polyhydric alcohol, lactitol. Lactulose is a commercial product, used for treatment of constipation.

Several million tons are produced annually as a by-product of the dairy industry. Whey is made up of 6.5% solids of which 4.8% is lactose, which is purified by crystallization. Whey or milk plasma is the liquid remaining after milk is curdled and strained, for example in the production of cheese. Lactose comprises about 2–8% of milk by weight. Industrially, lactose is produced from whey permeate – that is whey filtrated for all major proteins. The protein fraction is used in infant nutrition and sport nutrition while the permeate can be evaporated to 60–65% solids and crystallized while cooling Lactose can also be isolated by dilution of whey with ethanol.

Infant mammals nurse on their mothers to drink milk, which is rich in lactose. The intestinal villi secrete the enzyme lactase (β-D-galactosidase) to digest it. This enzyme cleaves the lactose molecule into its two subunits, the simple sugars glucose and galactose, which can be absorbed. Since lactose occurs mostly in milk, in most mammals, the production of lactase gradually decreases with maturity due to a lack of continuing consumption.

Many people with ancestry in Europe, West Asia, South Asia, the Sahel belt in West Africa, East Africa and a few other parts of Central Africa maintain lactase production into adulthood. In many of these areas, milk from mammals such as cattle, goats, and sheep is used as a large source of food. Hence, it was in these regions that genes for lifelong lactase production first evolved. The genes of adult lactose tolerance have evolved independently in various ethnic groups. By descent, more than 70% of western Europeans can drink milk as adults, compared with less than 30% of people from areas of Africa, eastern and south-eastern Asia and Oceania. In people who are lactose intolerant, lactose is not broken down and provides food for gas-producing gut flora, which can lead to diarrhea, bloating, flatulence, and other gastrointestinal symptoms.

Lactose intolerance is a condition in which people have symptoms due to the decreased ability to digest lactose a sugar found in milk products. Those affected vary in the amount of lactose they can tolerate before symptoms develop. Symptoms may include abdominal pain, bloating, diarrhea, gas, and nausea. These symptoms typically start between one half and two hours after drinking milk or eating milk products. Severity depends on the amount a person eats or drinks. It does not cause damage to the gastrointestinal tract.

Lactose intolerance is due to the lack of enzyme lactase in the small intestines to break lactose down into glucose and galactose. There are four types: primary, secondary, developmental, and congenital. Primary lactose intolerance occurs as the amount of lactase declines as people age. Secondary lactose intolerance is due to injury to the small intestine such as from infection, celiac disease, inflammatory bowel disease, or other diseases. Developmental lactose intolerance may occur in premature babies and usually improves over a short period of time. Congenital lactose intolerance is an extremely rare genetic disorder in which little or no lactase is made from birth.

Lactose intolerance primarily refers to a syndrome having one or more symptoms upon the consumption of food substances containing lactose. Individuals may be lactose intolerant to varying degrees, depending on the severity of these symptoms. “Lactose malabsorption” refers to the physiological concomitant of lactase deficiency (i.e., the body does not have sufficient lactase capacity to digest the amount of lactose ingested). Hypolactasia (lactase deficiency) is distinguished from alactasia (total lack of lactase), a rare congenital defect.

Lactose intolerance is not an allergy, because it is not an immune response, but rather a sensitivity to dairy caused by lactase deficiency. Milk allergy, occurring in only 4% of the population, is a separate condition, with distinct symptoms that occur when the presence of milk proteins trigger an immune reaction.

The principal symptom of lactose intolerance is an adverse reaction to products containing lactose (primarily milk), including abdominal bloating and cramps, flatulence, diarrhea, nausea, borborygmi, and vomiting (particularly in adolescents). These appear one-half to two hours after consumption. The severity of symptoms typically increases with the amount of lactose consumed; most lactose-intolerant people can tolerate a certain level of lactose in their diets without ill effects.

Lactose is also a commercial food additive used for its texture, flavor, and adhesive qualities. Lactose is often used as the primary filler (main ingredient) in most prescription and non-prescription solid pill form medications, though product labeling seldom mentions the presence of ‘lactose’ or ‘milk’, and neither do product monograms provided to pharmacists, and most pharmacists are unaware of the very wide scale yet common use of lactose in such medications until they contact the supplier or manufacturer for verification.

Lactose is digested by our digestive enzymes and absorbed into the body. It has its on caloric and nutritional values. It is by itself a drug substance as evident from our drug proving and symptomatology. It is not a chemically inert substance. It can cause a lot of adverse effects in human body. As a whole, it is obvious that Milk Sugar or Lactose is not an ideal dispensing vehicle for homeopathy drugs. A rethinking Is needed!

Elsewhere im my articles I have discussed about need of developing a new range of Molecular Imprinted Drugs using biological ligands  as the templates for imprinting.

Sarcodes used in homeopathy should be understood in terms of biological ligands they contain. When potentizing the sarcodes, we are actually producing Molecular Imprints of their constituent biological ligands.

First of all we have to understand why the molecular imprints of biological ligands are so much important as therapeutic agents.

All normal biological interactions being part of all biological processes actually happen by binding of a biological molecule with its natural ligands. Biological molecules such as cellular and intercellular  receptors, Various enzymes, transport molecules etc have bind with different natural ligand molecules to do their work.

These natural ligands have to bind to specific binding sites or active sites of the biological molecules in order to initiate a biochemical interaction between them. Various endogenous or exogenous alien molecules having conformational similarity with natural ligands can compete with natural ligands and produce a molecular inhibition, which amounts to a state of pathology. Since the competing pathogenic molecules and natural ligands have some conformational similarities, molecular imprints of natural ligands can obviously act as artificial binding pockets for those pathogenic molecules also. That is how the molecular imprints of natural ligands or sarcodes work as powerful therapeutic agents.

Two important questions have to be answered regarding sarcodes when considering from MIT perspective:

1. If sarcodes are natural biological ligands having specific functional roles in human organism, how they become pathogenic agents, requiring the intervention of their own potentized forms or ‘molecular imprints’?

2. If the sarcodes are biological ligands being essential parts of living system, will not their physiological functions get negatively affected by the use of their potentized forms, since it is true that potentized form of a drug substance can antidote the biological effects of same drug in crude form?

Let us consider pituitary hormones first. They play a decisive role in the whole metabolism of the organism, and hence called ‘master gland’. Pitutary hormones control many enzyme systems in our body. Then how can they act as pathogenic agents, requiring the use of potentized pituitary extract?

Next question is, when we use potentized pitutrin as a sarcode, will it not act as an antidote towards molecular forms of pituitary hormones and create dangerous
consequences, by disrupting the whole endocrine activities mediated by pituitary hormones?

Pepsinum is very important in digestion of proteins. If pepsinum 30 is given to a person, will it create problems in protein digestion by deactivating pepsin molecules? If they cannot antidote pepsin molecules, how can they act as therapeutic agents?

Thyroid hormones play very important roles in metabolic activities in the living organism. Then how it can be pathogenic agents, requiring the intervention of potentized thyroidinum? Will not potentized thyroidinum hinder the biological processes mediated by thyroid hormones?

These are very pertinent questions we have to answer while trying to explain the science behind using of potentized sarcodes.

We can answer these questions only if we know the dynamics of molecular processes involved in biochemical interactions.

Every biological molecules, especially those belonging to hormones, signaling molecules(cytokines), neuro-chemicals, antibodies and enzymes being circulated in the organism enter into two types of biological interactions:

1. ‘On-target interactions’ 2. ‘Off-target interactions’.

‘On-target’ interactions are those happening between natural ligands and their genuine natural biological targets. Such interactions are essential part of vital processes through which biochemical pathways are carried unhindered.

Natural ligands and their genuine targets interact through two steps:

a). molecular identification and binding, which is effected by complementary conformational affinity between targets and ligands,

b). actual chemical interaction, which is effected by perfect charge affinity between ligands and their natural targets.

Off-target interactions are those accidentally happening between ligands and wrong targets having conformational affinity only. In the absence of exact charge affinity, no chemical changes occur. Such interactions are always ‘inhibitory’, temporarily or permanently deactivating the involved biological molecules. Such ‘inhibitory’ off-target
interactions inevitably lead to derangement in associated biochemical pathways resulting in pathological states.

‘Off-target’ inhibitions caused by biological molecules such as hormones, enzymes, antibodies, signaling molecules(cytokines) and neurochemicals are causative
factors of a wide range of pathological conditions in living beings.

Sarcodes, or potentized preparations of these biological molecules, which contain their ‘molecular imprints’, can effectively remove these molecular inhibitions and thereby act as therapeutic agents. Here lies the importance of sarcodes in homeopathic
therapeutics.

Then comes the issue of selective action of the potentized sarcodes. As any other molecular imprints, molecular imprints in potentized sarcodes also cannot interfere in in the interactions between natural ligands and their genuine targets which involves conformational affinity as well as charge affinity. Since molecular imprints act through conformational affinity only, they can interfere in only inhibitory ‘off-target’ interactions.

It is now obvious that thyroidinum 30 cannot interfere in the essential biochemical processes mediated by thyroid hormones, Piturin 30 cannot interfere in the natural actions of pituitary hormones. This principle is applicable to all potentized sarcodes. We can use potentizeds arcodes above 12c without any fear of adverse effects.

Sarcodes or potentized biological ligands can play a very important role in the treatment of diverse types of diseases belonging to metabolic, emotional, psychosomatic, and ontological factors. They can also be part of constitutional prescriptions.

Pathogenic molecules cause diseases by binding to the biological targets and inhibiting their actions by mimicking as their natural ligands, due to the similarity of conformations of their functional groups.

Molecular Imprints of biological ligands can bind and deactivate the pathogenic molecules having functional groups similar to that of the biological ligands used for preparing the particular Molecular Imprints .

It is by this molecular mechanism that the molecular imprints of thyroid hormones contained in potentized THYROIDINUM removes the molecular inhibitions in the cellular receptors of thyroid hormones caused by pathogenic molecules.

We often experience cases where the patient shows symptoms of thyroid deficiency, but thyroid function tests will show normal production of thyroid hormones. It is a very confusing situation for physicians. What actually happens is, cellular receptors of thyroid hormones are blocked by some pathogenic molecules having functional groups similar to those of thyroid hormones binding to the receptors, presenting the interactions between thyroid hormones and their receptors.

If potentized THYROIDINUM.is applied in such cases, molecular imprints contained in the potentized drugs will bind to the pathogenic molecules, there by clearing the pathological inhibitions of receptors. Interactions between thyroid hormones and their biological targets are brought back to normal, and the deficiency symptoms of thyroid hormones are relieved.

It is by this same biological mechanism most of the HORMONE REMEDIES as well as the whole class of SARCODES used in homeopathy actually work. We should study SARCODES in terms of biological ligands they contain.

There is a confusion existing among homeopaths regarding the use of CACTUS in conditions of cardiac emergencies. Some people prefer to use mother tinctures and low potencies, whereas others prefer 30c and higher potencies.

CACTUS GRANDIFLOROUS or NIGHT-BLOOMING CEREUS is the plant from which our drug CACTUS is procured.

Raw CACTUS juice contains large amounts of Vitamin K, which contributes to the blood-clotting properties it displays during drug proving.

Potentized CACTUS contains molecular imprints of vitamin k, which help in reversing the blood clotting process by binding to vitamin k in the organism. Thereby CACTUS 30 gives instant relief in cardiac emergencies by dissolving blood clots that block the arteries.

Crude CACTUS was proved to have following actions:

1. Acts on circular muscular fibers, hence constrictions.

2. Favors formation of clots speedily.

These two actions are very much similar to what happens during a coronary artery blockage. Circular muscular fibres of coronary arteries suddenly contracts spasmodically, thereby narrowing the lumen of arteries. Blood clots forms and block these arteries, which results in the emergency situation.

That means, Molecular imprints contained in potenized CACTUS can reverse these processes happening during a heart attack. It relaxes the artery walls, dissolves the blood clots and facilitates the blood flow to cardiac muscles thereby preventing tissue death.

Frequent repetition is very important until tiding over the emergency situation.

During acute cardiac emergencies due to coronary artery blockage, give CACTUS 30 (dilution) in frequent doses until symptoms subside or expert medical care is made available. For last many years, I ask people in high risk group to always carry a 30ML bottle of CACTUS 30 (dilution) with them WITHIN REACH. Many of them had informed me that it had helped them to save their own life or others’ life during emergencies.

Never use CACTUS Q in such situations. It is expressly said in materia medica that “Cactus favors formation of blood clots speedily” during provings with crude forms. That means, “potentized Cactus can dissolve blood clots” according to similia similibus curentur.

See the Cardiac symptoms of CACTUS:

HANDBOOK OF MATERIA MEDICA- BOERICKE:

Acts on circular muscular fibers, hence constrictions.

*It is the heart and arteries especially that at once respond to the influence of Cactus, producing very characteristic constrictions as of an iron band.

This sensation is found in various places, oesophagus, bladder, etc.

The mental symptoms produced correspond to those found when there are heart affections, sadness, and melancholy.

Whole body feels as if caged, each wire being twisted tighter.

Atheromatous arteries and weak heart.

Congestions; irregular distribution of blood.

*Favors formation of clots speedily.

Great periodicity.

Toxic goitre with cardiac symptoms.

Cactus is pulseless, panting and prostrated.

*Fear of death.

Screams with pain.

Anxiety.

*Constriction of oesophagus.

Dryness of tongue, as if burnt; needs much liquid to get food down.

*Suffocative constriction at throat, with full, throbbing carotids in angina pectoris.

*Oppressed breathing as from a weight on chest.

*Constriction in chest, as if bound, hindering respiration.

Inflammation of diaphragm.

*Heart-constriction, as from an iron band.

Heart weakness of arterio-sclerosis.

Tobacco heart.

Violent palpitation; worse lying on left side, at approach of menses.

*Angina pectoris, with suffocation, cold sweat, and ever-present iron band feeling.

*Pain in apex, shooting down left arm.

*Palpitation, with vertigo; dyspnoea, flatulence.

*Constriction; very acute pains and stitches in heart; pulse feeble, irregular, quick, without strength.

*Angina pectoris.

*Palpitation; pain shooting down left arm.

Haemoptysis, with convulsive, spasmodic cough.

Diaphragmitis, with great difficulty of breathing.

*Numbness of left arm.

SYMPTOMS OF CACTUS GIVEN IN
DICTIONARY OF MATERIA MEDICA- CLARKE:

*Difficulty of breathing; continued oppression and uneasiness as if the chest were constricted with a (hot) iron band, hindering respiration.-Whirling sensation from chest to brain; arterial throbbing.-Oppressed breathing from a weight on chest.

*Congestion of the chest which prevents lying down; palpitation; constriction as from a tight cord around false ribs.

*Sensation of a great constriction in middle of sternum, as if the parts were compressed by iron pincers, with oppression of breathing; worse on motion.

*Constriction of throat exciting a constant desire to swallow.

*Suffocative constriction at throat with full, throbbing carotids.

*Pain deep in heart like a jerking body, frequently repeated.-

*Something seemed to be whirling up from chest to brain.-

*Sensation as if heart turned over ; as if it whirled round; as if some one was grasping heart firmly, with sensation as if it whirled round; as if heart was bound down and had not room enough to beat; as if bolts were holding it; as if compressed or squeezed by a band.-

*Lancinating pain in heart when perspiration fails.-

*Deathlike feeling at heart and round to l. back.-

*Acute pains, pricking and stitches in the heart.-

Palpitation of the heart, day and night; < when walking, and at night, when lying on l. side.-

Palpitation in small irregular beats (at times frequent, at others slow), from slightest excitement or deep thought, with necessity for deep inspiration.-

*Pains in apex of heart, shooting down l. arm to ends of fingers; feeble pulse; dyspnœa.-

Endocardial murmurs; excessive impulse; increased precordial dulness; enlarged ventricle.-

Heart disease with œdema of l. hand only.-

Aneurism.-Atheromatous arteries.Pain under l . shoulder-blade (with palpitation)

In Aphorisms 9 to 16 hahnemann explains his VITAL FORCE THEORY, which is actually a reassertion of unscientific philosophy of DYNAMISM that was a strong intellectual presence during his period. This part of ORGANON contributes much in making homeopathy incompatible with modern scientific knowledge, and it seems to be the greatest stumbling block in our efforts of making homeopathy a MEDICAL SCIENCE. This part of organon reflects the most primitive state of scientific knowledge that existed during hahnemann’s period. There is no doubt, if master had lived a few years later, he would have completely avoided this part from organon. In my opinion, these most unscientific aphorisms should be bracketed from new editions of organon being taught in our colleges, classifying it as only of historical interest. They should be replaced and updated with NEW scientific understanding of life, disease and cure, based on modern biochemistry and advanced life sciences.

For a scientific-minded person, there nothing to be seriously debated or argued in the ‘vital force theory’ in ORGANON, other than noting its historical premises and moved away into the archives.

READ Organon : Aphorism 9:

“In the healthy condition of man, the spiritual vital force (autocracy), the dynamis that animates the material body (organism), rules with unbounded sway, and retains all the parts of the organism in admirable, harmonious, vital operation, as regards both sensations and functions, so that our indwelling, reason-gifted mind can freely employ this living, healthy instrument for the higher purpose of our existence.”

My comments:

According to hahnemann, vital force is a ‘dynamis’ that ‘animates’ and ‘rules’ the ‘material body’. It is this vital force that “retains all the parts of the organism in admirable, harmonious, vital operation, as regards both sensations and functions”. As per this view, “material body” is only an “instrument” of “indwelling, reason-gifted mind”.

Hahnemann seems to think that the role of “material body” is limited to obeying the “rule” of vital force and act as an “instrument” of mind. He do not consider the molecular level structure, organization and chemical properties of the complex biological molecules constituting the ‘material body’ to play a role in the evolution of the phenomena he call ‘vital force’. He failed to understand that a ‘vital force’ cannot ‘animate’ a NON-LIVING ‘material body’ irrespective of its molecular level structure, organization and chemical properties? Actually, it is the STRUCTURE, ORGANIZATION and CHEMICAL PROPERTIES of complex biological molecules in the organism that initiate the MOLECULAR INTERACTIONS of ‘vital processes’ hahnemann call “vital force”. It is obvious that VITAL FORCE theory perceives biological processes upside down! At least, hahnemann should have noticed that this “all powerful” VITAL FORCE cannot “animate” MATERIAL BODIES if they have no a molecular level structure appropriate for the complex biological interactions constituting the vital processes.

Organon : Aphorism 10 : Sixth Edition:

“The material organism, without the vital force, is capable of no sensation, no function, no self-preservation1, it derives all sensation and performs all the functions of life solely by means of the immaterial being (the vital principle) which animates the material organism in health and in disease.

Foot notes:- It is dead, and only subject to the power of the external physical world; it decays, and is again resolved into its chemical constituents.”

My comments:

The most relevant question is, can this “immaterial” vital force ‘animate’ a metal body, a stone or a piece of wood and convert them into LIVING organisms, and give them ‘sensations’? Why vital force is capable of “animating” ONLY “material bodies” having a peculiar molecular structure and organization?

No ‘vital force’ can ‘animate’ a dead organism and bring it back to life, once the biochemical processes essential for normal vital functions are stopped and biological molecules are disorganized. All the functions you consider as vital force are seen only in highly organized organism constituted by complex biological molecules. It is the molecular level structure and organization of biological molecules and their interactions that impart properties of life to a ‘material body’. Vital force cannot animate a ‘material object’ in the absence of biological chemical molecules.

Organon : Aphorism 11 : Sixth Edition:

“When a person falls ill, it is only this spiritual, self acting (automatic) vital force, everywhere present in his organism, that is primarily deranged by the dynamic1 influence upon it of a morbific agent inimical to life; it is only the vital force, deranged to such an abnormal state, that can furnish the organism with its disagreeable sensations, and incline it to the irregular processes which we call disease; for, as a power invisible in itself, and only cognizable by its effects on the organism, its morbid derangement only makes itself known by the manifestation of disease in the sensations and functions of those parts of the organism exposed to the senses of the observer and physician, that is, by morbid symptoms, and in no other way can it make itself known.

Foot notes:- What is dynamic influence, – dynamic power? Our earth, by virtue of a hidden invisible energy, carries the moon around her in twenty-eight days and several hours, and the moon alternately, in definite fixed hours (deducting certain differences which occur with the full and new moon) raises our northern seas to flood tide and again correspondingly lowers them to ebb. Apparently this takes place not through material agencies, not through mechanical contrivances, as are used for products of human labor; and so we see numerous other events about us as results of the action of one substance on another substance without being able to recognize a sensible connection between cause and effect. Only the cultured, practised in comparison and deduction, can form for himself a kind of supra-sensual idea sufficient to keep all that is material or mechanical in his thoughts from such concepts. He calls such effects dynamic, virtual, that is, such as result from absolute, specific, pure energy and action of the one substance upon the other substance.

For instance, the dynamic effect of the sick-making influences upon healthy man, as well as the dynamic energy of the medicines upon the principle of life in the restoration of health is nothing else than infection and so not in any way material, not in any way mechanical. Just as the energy of a magnet attracting a piece of iron or steel is not material, not mechanical. One sees that the piece of iron is attracted by one pole of the magnet, but how it is done is not seen. This invisible energy of the magnet does not require mechanical (material) auxiliary means,

hook or lever, to attract the iron. The magnet draws to itself and this acts upon the piece of iron or upon a steel needle by means of a purely immaterial invisible, conceptual, inherent energy, that is, dynamically, and communicates to the steel needle the magnetic energy equally invisibly (dynamically). The steel needle becomes itself magnetic, even at a distance when the magnet does not touch it, and magnetises other steel needles with the same magnetic property (dynamically) with which it had been endowered previously by the magnetic rod, just as a child with small-pox or measles communicates to a near, untouched healthy child in an invisible manner (dynamically) the small-pox or measles, that is, infects it at a distance without anything material from the infective child going or capable of going to the one to be infected. A purely specific conceptual influence communicated to the near child small-pox or measles in the same way as the magnet communicated to the near needle the magnetic property.

In a similar way, the effect of medicines upon living man is to be judged. Substances, which are used as medicines, are medicines only in so far as they possess each its own specific energy to alter the well-being of man through dynamic, conceptual influence, by means of the living sensory fibre, upon the conceptual controlling principle of life. The medicinal property of those material substances which we call medicines proper, relates only to their energy to call out alterations in the well-being of animal life. Only upon this conceptual principle of life, depends their medicinal health-altering, conceptual (dynamic) influence. Just as the nearness of a magnetic pole can communicate only magnetic energy to the steel (namely, by a kind of infection) but cannot commu nicate other properties (for instance, more hardness or ductility, etc.). And thus every special medicinal substance alters through a kind of infection, that well-being of man in a peculiar manner exclusively its own and not in a manner peculiar to another medicine, as certainly as the nearness of the child ill with small-pox will communicate to a healthy child only small-pox and not measles.

These medicines act upon our well-being wholly without communication of material parts of the medicinal substances, thus dynamically, as if through infection. Far more healing energy is expressed in a case in point by the smallest dose of the best dynamized medicines, in which there can be, according to calculation, only so little of material substance that its minuteness cannot be thought and conceived by the best arithmetical mind, than by large doses of the same medicine in substance.

That smallest dose can therefore contain almost entirely only the pure, freely-developed, conceptual medicinal energy, and bring about only dynamically such great effects as can never be reached by the crude medicinal substances itself taken in large doses.

It is not in the corporal atoms of these highly dynamized medicines, nor their physical or mathematical surfaces (with which the higher energies of the dynamized medicines are being interpreted but vainly as still sufficiently material) that the medicinal energy is found. More likely, there lies invisible in the moistened globule or in its solution, an unveiled, liberated, specific, medicinal force contained in the medicinal substance which acts dynamically by contact with the living animal fibre upon the whole organism (without communicating to it anything material however highly attenuated) and acts more strongly the more free and more immaterial the energy has become through the dynamization.

Is it then so utterly impossible for our age celebrated for its wealth in clear thinkers to think of dynamic energy as something non-corporeal, since we see daily phenomena which cannot be explained in any other manner?

If one looks upon something nauseous and becomes inclined to vomit, did a material emetic come into his stomach which compels him to this anti-peristaltic movement? Was it not solely the dynamic effect of the nauseating aspect upon his imagination? And if one raises his arm, does it occur through a material visible instrument? a lever? Is it not solely the conceptual dynamic energy of his will which raises it?”

My Comments:

Listen to this statement, which amounts to a confession by Hahnemann: “think of dynamic energy as something non-corporeal, since we see daily phenomena which cannot be explained in any other manner”. That clearly explains how Hahnemann happened to “think of dynamic energy as something non-corporeal” It was only “since we see daily phenomena which cannot be explained in any other manner”! He was compelled to explain homeopathy using concepts of “dynamic energy” and “vital force”, only because he could not explain the phenomena of cure he observed, using “any other manner”! This statement constitutes a great historical truth.

In my opinion, foot note of aphorism 11 is a severe self-insult Hahnemann inflicted upon his own credibility, as it contains a lot of most irrational and unscientific statements that reflects the limitations of scientific knowledge available to him.

Please read carefully the following statements I quoted from this most unscientific and most unwanted foot-note:

“Our earth, by virtue of a hidden invisible energy, carries the moon around her”

“moon raises our northern seas to flood tide and again correspondingly lowers them to ebb by a hidden invisible energy”

“we see numerous other events about us as results of the action of one substance on another substance without being able to recognize a sensible connection between cause and effect.”

“calls such effects dynamic, virtual, that is, such as result from absolute, specific, pure energy and action of the one substance upon the other substance.”

“For instance, the dynamic effect of the sick-making influences upon healthy man, as well as the dynamic energy of the medicines upon the principle of life in the restoration of health is nothing else than infection and so not in any way material, not in any way mechanical. “

“the energy of a magnet attracting a piece of iron or steel is not material, not mechanical.”

“the piece of iron is attracted by one pole of the magnet, but how it is done is not seen.”

“The magnet draws to itself and this acts upon the piece of iron or upon a steel needle by means of a purely immaterial invisible, conceptual, inherent energy, that is, dynamically, and communicates to the steel needle the magnetic energy equally invisibly (dynamically).”

“a child with small-pox or measles communicates to a near, untouched healthy child in an invisible manner (dynamically) the small-pox or measles, that is, infects it at a distance without anything material from the infective child going or capable of going to the one to be infected. A purely specific conceptual influence communicated to the near child small-pox or measles in the same way as the magnet communicated to the near needle the magnetic property.”

“Substances, which are used as medicines, are medicines only in so far as they possess each its own specific energy to alter the well-being of man through dynamic, conceptual influence, by means of the living sensory fibre, upon the conceptual controlling principle of life “

“The medicinal property of those material substances which we call medicines proper, relates only to their energy to call out alterations in the well-being of animal life.”

“Only upon this conceptual principle of life, depends their medicinal health-altering, conceptual (dynamic) influence, just as the nearness of a magnetic pole can communicate only magnetic energy to the steel, namely, by a kind of infection.”

“every special medicinal substance alters through a kind of infection, that well-being of man in a peculiar manner exclusively its own and not in a manner peculiar to another medicine, as certainly as the nearness of the child ill with small-pox will communicate to a healthy child only small-pox and not measles. “

“These medicines act upon our well-being wholly without communication of material parts of the medicinal substances, thus dynamically, as if through infection”

“That smallest dose can therefore contain almost entirely only the pure, freely-developed, conceptual medicinal energy, and bring about only dynamically such great effects as can never be reached by the crude medicinal substances itself taken in large doses”

“It is not in the corporal atoms of these highly dynamized medicines, nor their physical or mathematical surfaces that the medicinal energy is found. “

“there lies invisible in the moistened globule or in its solution, an unveiled, liberated, specific, medicinal force contained in the medicinal substance which acts dynamically by contact with the living animal fibre upon the whole organism (without communicating to it anything material however highly attenuated) and acts more strongly the more free and more immaterial the energy has become through the dynamization.”

“If one looks upon something nauseous and becomes inclined to vomit, did a material emetic come into his stomach which compels him to this anti-peristaltic movement? Was it not solely the dynamic effect of the nauseating aspect upon his imagination?”

“And if one raises his arm, does it occur through a material visible instrument? a lever? Is it not solely the conceptual dynamic energy of his will which raises it?”

IF YOU READ ALL THESE SENTENCES I QUOTED FROM ABOVE FOOT NOTE, YOU WILL REALIZE WHY I CONSIDER THIS FOOT NOTE AS A SELF-INFLICTED INSULT UP ON CREDENTIALS OF OUR MASTER.

Organon : Aphorism 12 : Sixth Edition:

“It is the morbidly affected vital energy alone that produces disease, so that the morbid phenomena perceptible to our senses express at the same time all the internal change, that is to say, the whole morbid derangement of the internal dynamis; in a word, they reveal the whole disease; consequently, also, the disappearance under treatment of all the morbid phenomena and of all the morbid alterations that differ from the healthy vital operations, certainly affects and necessarily implies the restoration of the integrity of the vital force and, therefore, the recovered health of the whole organism.

Foot notes:- How the vital force causes the organism to display morbid phenomena, that is, how it produces disease, it would be of no practical utility to the physician to know, and will forever remain concealed from him; only what it is necessary for him to know of the disease and what is fully sufficient for enabling him to cure it, has the Lord of life revealed to his senses”

My Comments:

Regarding the question “how vital force causes disease”, Hahnemann declares “it would be of no practical utility to the physician to know, and will forever remain concealed”. Up on god, he says the physician should try to know only “what it is necessary for him to know of the disease and what is fully sufficient for enabling him to cure it”! Lazy and dogmatic homeopaths love to quote this statement frequently to cover up their inability to answer “how homeopathy works”. According to them, our master has eternally forbidden us from asking such questions!

Organon : Aphorism 13:

“Therefore disease (that does not come within the province of manual surgery) considered, as it is by the allopathists, as a thing separate from the living whole, from the organism and its animating vital force, and hidden in the interior, be it ever so subtle a character, is an absurdity, that could only be imagined by minds of a materialistic stamp, and has for thousands of years given to the prevailing system of medicine all those pernicious impulses that have made it a truly mischievous (non-healing) art.”

My comments:

Hahnemann considers asking questions about the inner processes of disease is an “absurdity” “imagined by minds of a materialistic stamp”, and it is this “materialistic mind” that made “the prevailing system of medicine” “a truly mischievous (non-healing) art.”

Organon : Aphorism 14 : Sixth Edition:

“There is, in the interior of man, nothing morbid that is curable and no invisible morbid alteration that is curable which does not make itself known to the accurately observing physicians by means of morbid signs and symptoms – an arrangement in perfect conformity with the infinite goodness of the all-wise Preserver of human life.”

My comments:

“”There is, in the interior of man, nothing morbid that is curable and no invisible morbid alteration that is curable which does not make itself known to the accurately observing physicians by means of morbid signs and symptoms”- It is a correct statement even valid from modern scientific point of view, even if we discard the vitalistic interpretations of Hahnemann.

Organon : Aphorism 15 : Sixth Edition:

“The affection of the morbidly deranged, spirit-like dynamis (vital force) that animates our body in the invisible interior, and the totality of the outwardly cognizable symptoms produced by it in the organism and representing the existing malady, constitute a whole; they are one and the same. The organism is indeed the material instrument of the life, but it is not conceivable without the animation imparted to it by the instinctively perceiving and regulating dynamis, just as the vital force is not conceivable without the organism, consequently the two together constitute a unity, although in thought our mind separates this unity into two distinct conceptions for the sake of easy comprehension.”

My comments:

I would suggest to modify this aphorism as follows: “”The affection of the morbidly deranged molecular level vital processes, and the totality of the outwardly cognizable symptoms produced by it in the organism and representing the existing malady, constitute a whole; they are one and the same. The molecular processes in the organism are indeed the material basis of the phenomenon life.

Homeopathy can exist even without vital force theory. Actually, it becomes more rational and scientific by replacing the concept of ‘vital force’ with modern scientific understanding of ‘molecular level biochemical vital processes’.

Organon : Aphorism 16 : Sixth Edition:

“Our vital force, as a spirit-like dynamis, cannot be attacked and affected by injurious influences on the healthy organism caused by the external inimical forces that disturb the harmonious play of life, otherwise than in a spirit-like (dynamic) way, and in like manner, all such morbid derangements (diseases) cannot be removed from it by the physician in any other way than by the spirit-like (dynamic1, virtual) alterative powers of the serviceable medicines acting upon our spirit-like vital force, which perceives them through the medium of the sentient faculty of the nerves everywhere present in the organism, so that it is only by their dynamic action on the vital force that remedies are able to re-establish and do actually re-establish health and vital harmony, after the changes in the health of the patient cognizable by our senses (the totality of the symptoms) have revealed the disease to the carefully observing and investigating physician as fully as was requisite in order to enable him to cure it.

Foot notes:- Most severe disease may be produced by sufficient disturbance of the vital force through the imagination and also cured by the same means.”

My Comments:

Hahnemann says: “alterative powers of the serviceable medicines acting upon our spirit-like vital force, which perceives them through the medium of the sentient faculty of the nerves everywhere present in the organism”. According to this view, homeopathic potentized drugs act through “sentient nerves”. But research works proved otherwise. Researchers have proved that potentized drugs act even up on in vitro biological samples which do not contain any ‘sentient nerves’ or nerve cells. There are enough scientific evidences now to prove that potentized drugs act up on biological molecules- not merely ‘sentient nerves’.

Hahnemann’s statement “disease may be produced by sufficient disturbance of the vital force through the imagination and also cured by the same means” actually explains the phenomena of so-called psychosomatic diseases, which are well explained by biochemistry, without any involvement of vital force theory. According to scientific view, “imaginations’ and “emotoions” are not “non-material” What we call ‘emotions’ and ‘sensations’ are actually very complex biochemical processes happening in our brain. There is nothing ‘immaterial’ in ‘emotions’ and other mental processes. During those biochemical processes, different types of chemical molecules are synthesized and utilized by the central nervous system, such as hormones, cytokines, neuro-mediators and neurotransmitters etc. What we call ‘bad effects’ of emotions are actually the delayed, off-target or rebound chemical actions of these biochemical molecules. Biochemistry can explain such phenomena without any involvement of any ‘immaterial’ or ‘dynamic’ vital force.

Pepsin is a protein-degrading or proteolytic enzyme in the digestive system. Pepsin is released by the cells in the stomach. This enzyme degrades food proteins into peptides to facilitate absorption. Pepsin is a digestive protease, a member of the aspartate protease family. During the process of digestion, pepsin severs the links between particular types of amino acids, collaborate to break down dietary proteins into their components, i.e., peptides and amino acids, which can be readily absorbed by the intestinal lining. Pepsin is most efficient in cleaving peptide bonds between hydrophobic and preferably aromatic amino acids such as phenylalanine, tryptophan, and tyrosine.

Pepsin is expressed as a pro-form zymogen, pepsinogen, whose primary structure has an additional 44 amino acids. In the stomach, chief cells release pepsinogen. This zymogen is activated by hydrochloric acid (HCl), which is released from parietal cells in the stomach lining. The hormone gastrin and the vagus nerve trigger the release of both pepsinogen and HCl from the stomach lining when food is ingested. Hydrochloric acid creates an acidic environment, which allows pepsinogen to unfold and cleave itself in an autocatalytic fashion, thereby generating pepsin (the active form). Pepsin cleaves the 44 amino acids from pepsinogen to create more pepsin.

Pepsin is most active in acidic environments between 37°C and 42°C. Accordingly, its primary site of synthesis and activity is in the stomach (pH 1.5 to 2). Pepsin exhibits maximal activity at pH 2.0 and is inactive at pH 6.5 and above, however pepsin is not fully denatured or irreversibly inactivated until pH 8.0. The stability of pepsin at high pH has significant implications on disease attributed to laryngopharyngeal reflux. Pepsin remains in the larynx following a gastric reflux event. At the mean pH of the laryngopharynx pH = 6.8 pepsin would be inactive but could be reactivated upon subsequent acid reflux events resulting in damage to local tissues.

Pepsin is one of the primary causes of mucosal damage during laryngopharyngeal reflux.  Pepsin remains in the larynx pH 6.8 following a gastric reflux event. While enzymatically inactive in this environment, pepsin would remain stable and could be reactivated upon subsequent acid reflux events. Exposure of laryngeal mucosa to enzymatically active pepsin, but not irreversibly inactivated pepsin or acid, results in reduced expression of protective proteins and thereby increases laryngeal susceptibility to damage.

Pepsin may also cause mucosal damage during weakly acidic or non-acid gastric reflux. Weak or non-acid reflux is correlated with reflux symptoms and mucosal injury. Under non-acid conditions (neutral pH), pepsin is internalized by cells of the upper airways such as the larynx and hypopharynx by a process known as receptor-mediated endocytosis.  Upon cellular uptake, pepsin is stored in intracellular vesicles of low pH at which its enzymatic activity would be restored. Pepsin is retained within the cell for up to 24 hours. Such exposure to pepsin at neutral pH and endoyctosis of pepsin causes changes in gene expression associated with inflammation, which underlies signs and symptoms of reflux, and tumor progression. This and other research implicates pepsin in carcinogenesis attributed to gastric reflux.

Pepsin is found in the saliva of persons suffering from gastro-esophageal reflux, which causes persistent corroding of buccal mucosa, leading to deep ulcers of mouth cavity.

Commercial pepsin is extracted from the glandular layer of hog stomachs. It is a component of rennet used to curdle milk during the manufacture of cheese. Pepsin is used for a variety of applications in food manufacturing: to modify and provide whipping qualities to soy protein and gelatin, to modify vegetable proteins for use in nondairy snack items, to make precooked cereals into instant hot cereals, and to prepare animal and vegetable protein hydrolysates for use in flavoring foods and beverages. It is used in the leather industry to remove hair and residual tissue from hides and in the recovery of silver from discarded photographic films by digesting the gelatin layer that holds the silver. Pepsin was historically an additive of  chewing gum. It also gave name to Pepsi-Cola, originally formulated with pepsin and cola nuts.

PEPSINUM is the homeopathic preparation prepared by potentizing PEPSIN. In potentized forms, it contains MOLECULAR IMPRINTS of pepsin molecules. Potentized PEPSINUM above 12C could be used in the treatment of GERD, to heal the mucosal damage caused laryngopharyngeal reflux. It  is also useful in the treatment of gastric ulcers, esophagitis, esophageal ulcerations and strictures, esophageal and laryngeal carcinoma etc.

Personally, I have regularly used PEPSINUM 30 successfully in the treatment of GASTRITIS, GASTRIC ULCER and ESOPHAGITIS and deep ulcers of buccal cavity.

While attacking homeopathy on social media platforms, we hear most skeptics frequently referring to a particular document called NHMRC report as an authoritative sacred evidence for their argument that homeopathy has no right to exist as a medical system. 

I have just in front of me that ‘NHMRC INFORMATION PAPER- Evidence on the effectiveness of homeopathy for treating health conditions’ published in March 2015 by National Health and Medical Research Council, Australia, claimed to be published after an elaborate study of all published materials about homeopathy. (http://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/cam02a_information_paper.pdf ). I have been studying it minutely for the last few days, along with all its appended documents.

It is really terrifying to see how ‘scientific method’ and its ‘golden rules’ are misused by powerful people to crush simple truth of homeopathy, and to shield their vested anti-people business interests in healthcare industry. It is disheartening to see how the respected ‘men of science’ and ‘democratic rulers’ have turned mere puppets of global healthcare corporate kings and greedy big pharma giants. I am totally shattered to witness this dark ‘other side’ of science and democracy which I cherished so much all my life.

Learned NHMRC ‘hired’ pundits have given their final verdict of homeopathy in this ‘Information Paper’: “Homeopathy is Good for Nothing!” It is “Nothing better than Placebo!” Homeopathy should not exist!

NHMRC report concludes that there is no reliable evidence from research in humans that homeopathy is effective for treating the range of health conditions considered. There were no health conditions for which there was reliable evidence that homeopathy was effective. According to them, Homeopathy should not be used to treat health conditions that are chronic, serious, or could become serious. It is warned that people who choose homeopathy may put their health at risk if they reject or delay treatments for which there is good evidence for safety and effectiveness.

According to the NHMRC, some studies reported that homeopathy was more effective than placebo, or as effective as another treatment, but they rejects such positive reports saying that those studies were not reliable, and declared that, be confident that the reported health benefits of homeopathy were not just due to chance or the placebo effect, they would need to be confirmed by other well-designed studies with an adequate number of participants. Report further says that for health conditions it was not possible to make any conclusion about whether homeopathy was effective or not, because there was not enough evidence.”

It is obvious that even after a lot of biased intellectual exercises, NHRMC could not rule out homeopathy completely. Only thing they could say is that positive effects of homeopathy “would need to be confirmed by other well-designed studies with an adequate number of participants”, and that “it was not possible to make any conclusion about whether homeopathy was effective or not, because there was no enough evidence.” Our sceptic friends conveniently ignore these pieces of observations in NHMRC report!

After going through the NHMRC Information Paper as well as the appended documents carefully, I feel that NHMRC showed some sort of undue haste in arriving at such a totally negative conclusion regarding the effectiveness of homeopathy. They seem to be more inclined towards ‘excluding’ materials and evidences rather than evaluating them, and declare all seemingly positive evidences as “inconclusive” and “unreliable”. This hurry sparks doubts in the minds of impartial observers regarding the real goal of this project. Important question is, is it appropriate for scientific method to utilize ‘lack of sufficient evidence’ as an ‘evidence against’ homeopathy? Did NHMRC ‘search for truth of homeopathy’, or search for ‘evidences against homeopathy’?

Before advancing further with this critique, we have to know the people who worked behind this ‘Information Paper’, and their real objectives in taking up a work of this type, that may have catastrophic effects up on a low-cost medical system currently accepted by millions of people around the world for their day to day health care requirements. It is very serious, since the ‘paper’ recommends that “homeopathy should not be used to treat health conditions”! It is so serious that recommendations made in this paper may be utilized by interested parties to undermine even the very existence of homeopathy as a system of medical practice. Before declaring homeopathy is ineffective, NHMRC should have conducted some well designed studies and researches of their own, instead of arriving at hasty conclusions from assessments of already ‘published materials’ only, that too by hired ‘contractors’. I wonder what held them back from doing this, if they were really dedicated to finding out truth in the common interest of the society! At least in the interest of finding truth, they could have concluded their report by recommending the scientific community to undertake serious research works on homeopathy, since all the works so far done were found to be ‘methodologically flawed’, ‘unreliable’ and ‘inconclusive’! NHMRC introduced themselves as follows: “NHMRC is Australia’s peak body for supporting health and medical research by funding the best research, selected through a competitive peer review process. 

NHMRC also develops health advice for the Australian community, health professionals and governments in the form of public health and clinical practice guidelines, Statements, Information Papers and evidence reviews. NHMRC also provides advice on ethical behavior in health care and in the conduct of health and medical research. The work of NHMRC is guided by its Strategic Plan, and defined by the National Health and Medical Research Council (NHMRC) Act 1992. The Strategic Plan covers a three year period and is submitted to the Health Minster for approval, prior to being tabled in Parliament. The NHMRC Strategic Plan 2013–2015 has identified ‘claiming benefit for human health not based on evidence’ as a major health issue for consideration.”

According to them, “this Information Paper is an example of NHMRC’s function to ‘advise the community’ under section 7(1)(a) of the NHMRC Act 1992. Published research on a topic of interest has been identified, analyzed and synthesized into a summary of the evidence for the Australian community, health professionals and policy makers. This information can then be utilized to assist people in making healthcare choices, guide clinical practice or influence policy and perhaps new funding approaches, all of which lead to improvements in health and health care delivery. Within our health system, there are practices which are currently not based on sturdy evidence. Health and medical research is the means by which we test the value of procedures, processes, systems and products offered to patients, or proposed as preventive means by the health system and its policy and decision makers.

NHMRC is a strong advocate for the development and use of evidence to inform policy and practice and in recent years, NHMRC and other health research funding bodies have increased funding for such research. NHMRC is of the view that when offering treatments for illness, all registered health practitioners must give consideration to the evidence for the effectiveness of such treatments. This consideration should be reflected in their professional ethics and clinical practices.”

According to the NHMRC, the current ‘Information Paper’ is the outcome of their assessment of the evidence of the effectiveness of homeopathy, based on: a) an overview of published systematic reviews by an independent contractor, b) an independent evaluation of information provided by homeopathy interest groups and the public, and, c) consideration of clinical practice guidelines and government reports on homeopathy published in other countries. Kindly do not misunderstand, NHMRC did not conduct any research by themselves about homeopathy that led them to a judgment. It was only an “assessment” based on available published materials, as reviewed by “independent contractor”.
Why did NHMRC conduct such an ‘assessment’ of homeopathy? Listen what they say: “NHMRC is responsible for supporting health and medical research as well as providing Australians with advice based on best available evidence. This advice assists people in making informed decisions about their health care. This includes providing advice about the use of conventional therapies, as well as complementary and alternative medicines or traditional practices which, despite their longstanding history of use, may not have been demonstrated to be effective.

Many health care practices and products are promoted as beneficial to health when there is little or no evidence to support these claims. In some cases these claims may mislead people to reject practices and treatments that are proven to be effective, in favor of non-evidence-based treatments. People who use homeopathy need to understand the potential benefits and risks to enable them to make an informed decision. Health practitioners also need to know what homeopathy is, be aware of the current scientific evidence from research on homeopathy, and understand any possible benefits and risks to patients—particularly when people decide to use homeopathy instead of other evidence-based treatments. For these reasons, NHMRC undertook an assessment of the evidence to provide Australians with reliable information on the effectiveness of homeopathy”.

I repeat my question once again: Why NHMRC did not conduct some well designed studies and researches of their own regarding the effectiveness of homeopathy, instead of arriving at hasty conclusions from assessments of already ‘published materials’ only, knowing well that they are ‘unreliable’ due to flawed methodology, that too by hired ‘contractors’? What held them back from taking up this most important task, if they were really dedicated to finding out truth in the common interest of the society! Why a responsible body such as NHMRC could not hire a team to conduct such a research work strictly following the scientific methodology, so that ‘reliable’ and ‘conclusive’ output is ensured? If people at NHMRC were genuinely interested to know whether homeopathy works or not, it would have been the easiest way for them, rather than searching for ‘unreliable’ databases!

Only imaginable reason is, NHMRC actually wanted to build a defenceless case against homeopathy, rather than finding out the truth! It was their only goal mandated by their bosses- nothing else!

This work was overseen by the ‘Homeopathy Working Committee’ established by the NHMRC. This working committee “gave their collective expertise in evidence-based medicine, study design, and complementary and alternative medicine research. Homeopathy Working Committee also provided advice on how the evidence should be interpreted in developing an Information Paper.”
It is very crucial to know who were the “experts” that constituted this “homeopathic working committee”, who “provided advice on how the evidence should be interpreted in developing a Information Paper” on this very important topic. Were there any homeopathy expert included in this “homeopathy working committee”?

Let us see the list of Committee members and their credentials given in the Information Paper:1. Professor Paul Glasziou, MBBS, PhD, FRACGP, General practitioner Professor and Director of the Centre for Research into EvidenceBased Practice, Bond University, Queensland Expert in evidence-based medicine.
2. Professor Peter Brooks, AM, MBBS, MD (Lund), FRACP, FAFRM, FAFPHM, MDHonCausa, FRCP (Glas, Edin), Rheumatologist Director of the Australian Health Workforce Institute, University of Melbourne, Victoria (to September 2013) Executive Director Research, Northern Hospital, Epping, Victoria Former board member, Australian Centre for Complementary Medicine Education and Research, University of Queensland.

3. Professor Frederick Mendelsohn, AO, MB BS, PhD, MD, FRACP Neuroscientist Former Chair in Medicine and Director of the Howard Florey Institute, University of Melbourne, Victoria.

4. Mr John Stubbs, BA, DipAcct Consumer Executive Officer, canSpeak Honorary Associate, School of Medicine, University of Sydney, New South Wales Member, Australian Health Ethics Committee, NHMRC Member, Consumer Consultative Group, NHMRC.

5. Associate Professor Evelin Tiralongo, BPharm(Hons), PhD, GradCertHigherEd Pharmacist Discipline head for complementary medicine teaching and research, School of Pharmacy and Griffith Health Institute, Griffith University, Gold Coast, Queensland Member, Clinical Trials Coordinating Centre, Griffith University Member, Society for Medicinal Plant and Natural Product Research.

6. Dr Nikolajs Zeps, BSc(Hons), PhD Research scientist Director, St John of God Subiaco Hospital Research network Adjunct Professor School of Health Sciences, Curtin University Adjunct Professor, Centre for Comparative Genomics, Murdoch University Adjunct Associate Professor, School of Surgery and School of Pathology and Laboratory Medicine, University of Western Australia Adjunct Associate Professor, Faculty of Medicine, University of Notre Dame, Western Australia Founding Director, Australian Clinical Trials Alliance Member, Research Committee, NHMRC Member, Australian Health Ethics Committee, NHMRC: Triennium 2010–2012.

7. Professor Chris Baggoley, AO, BVSc(Hons), MBBS, BSocAdmin, FACEM, FIFEM , Australian Government Chief Medical Officer.

It is wonderful to note that out of these SEVEN ‘experts’, nobody belongs to the homeopathic community, or claims to have any ‘expertise’ or ‘knowledge’ about homeopathy. All of them belong to modern medical community, who represent a community having known ‘prejudices’ and ‘biases’ against homeopathy. Yet, the committee is called ‘Homeopathic Working Committee’! It is really a big fun to hear calling a body of ‘anti-homeopathic experts’ as ‘Homeopathic Working Committee! If their intentions were genuine, NHMRC should have included in this committee a couple of persons having expertise in homeopathy also, at least to give them a say and prove that there is no bias against homeopathy. Anti-homeopathic goal of NHMRC in taking up this task of ‘assessing’ homeopathy is evident from the constitution of this working committee itself.

Let us come to the methodological aspects of NHMRC ‘assessment’. It is consented that the assessment was based on “an overview of published systematic reviews by an independent contractor”. That means, it was that “independent contractor” who conducted the “overview of published systematic reviews” that led to the publication of this ‘Information Paper’.
NHMRC mentions in their ‘paper’ that they commissioned a professional research group Optum Insight (Optum) to do a thorough search of published research to find systematic reviews of studies (prospective, controlled studies) that compared homeopathy with no homeopathy or with other treatments and measured effectiveness in patients with any health condition. That means, OPTUM is the “independent contractor”.

Our study of NHMRC ‘Information Paper’ and their conclusions will not be complete unless we know the people behind OPTUM, whom NHMRC hired as “impartial contractors” to do the whole work. Then only you will understand that it is not an issue of ‘prejudice’ and ‘skeptic bias’, but a pre-planned, state-mediated, well financed, global conspiracy against homeopathy, sponsored by international pharmaceutical lobbies. OPTUM is not “impartial contractors” or “hired researchers” as NHMRC tries to make out, but the real players with their own vested interests, who conducted and orchestrated the whole event for their powerful patrons in the big pharma and healthcare industry.

OPTUM introduces themselves in their website as a “health services and innovation company on a mission, with 94,000 people dedicated to improving the health system for everyone in it, powering MODERN HEALTHCARE by combining data and analytics with technology and expertise”. Visit http://www.optum.com to know the real role and stakes of this giant in global modern health care business. OPTUM is a leading information and technology-enabled corporate health services business house with diverse interests and different areas of health care industry, including drug development, clinical trials, pharmaceuticals as well as medical insurance. They also run their own pharma industry house known as ‘OptumRx’. OPTUM has a colossal presence in different spheres of international health care industry, mostly interested in eradicating all complementary medical systems including HOMEOPATHY, which may pose threat to their big pharma interests.

Now the picture is very clear. OPTUM is not “impartial contractors” or ‘job workers’ hired by NRHMC, but the executors of a global scale health industry conspiracy to “finish” HOMEOPATHY. Entrusting a team of anti-homeopathic experts as well as OPTUM for making “assessment” regarding effectiveness of homeopathy was actually like appointing jackals as the caretakers of chickens!

The researchers of OPTUM searched databases of health publications to find systematic reviews published in English between 1 January 1997 and 3 January 2013. For each health condition, the research group collated the findings of the systematic reviews and assessed the quality and reliability of the evidence. The findings are described in detail in the Overview Report. The purpose of this approach was to use published systematic reviews as a way of identifying the body of evidence for homeopathic treatments. The professional research group of OPTUM did not accept the conclusions or interpretations of the systematic reviews, but instead considered the included studies. The professional research group evaluated the quality of each of the included studies, using the information provided by the systematic reviews.

Additional information was submitted by homeopathy interest groups and the public to NHMRC, for its consideration as a part of its review of homeopathy, on two occasions. The preliminary submitted literature on the effectiveness of homeopathy was provided by the Australian Homoeopathy Association and the Australian Medical Fellowship of Homeopathy as well as members of the public. During public consultation on the draft Information Paper, a range of stakeholders submitted 12 additional literature for consideration in the development of this Information Paper .

All submitted literature was assessed by OPTUM researchers to identify evidence within the scope of NHMRC’s assessment. Only the types of studies that were included in the overview (prospective, controlled studies) were assessed in detail. For each study included, OPTUM assessed the quality and reliability of the results and summarized the findings in a review of submitted literature. This evidence was considered when preparing this Information Paper.

If you go though the whole report, you will see how effectively and professionally OPTUM has done the work they were entrusted to do. Final outcome was pre-determined, and all “assessments” were aimed at that goal. Entrusting OPTUM as well as experts of anti-homeopathic professional interests for the ‘assessment’ of effectiveness homeopathy has actually proved to be like appointing ‘jackals’ as the caretakers of ‘chicken’!

See how the OPTUM researchers dealt with the 343 articles submitted by homeopathy interest groups and individuals and produced a BIG ZERO from them: “A total of 343 articles were submitted to NHMRC, of which a large majority (234) were of a research or publication type not meeting the inclusion criteria. A further 79 articles had already been included or considered in the Overview Report. On considering the remaining 30 articles, studies were excluded if they: covered an intervention not meeting the inclusion criteria; were of a research type not meeting the inclusion criteria; did not report on efficacy outcomes; the study design confounded the results; or were not published in English. This resulted in nine studies examining the effectiveness of homeopathy for the treatment of eight different clinical conditions identified for further assessment. Five of the eight conditions (otitis media, delayed-onset muscle soreness, depression, bruising, and sleep or circadian rhythm disturbances) were examined in the overview. The results of these studies were considered in relation to the body of evidence identified in the overview but did not alter the overall conclusions about the effectiveness of homeopathy because of their poor quality, poor design, poor reporting of the study design or method, or too few participants.”

See the fate of ‘public consultation’ submitted literature: “A total of 48 submissions were received from consumers, consumer groups, health care professionals, homeopathy practitioners and homeopathy organisations. Of the 153 articles cited in these submissions, 94 were excluded because they did not meet the criteria for the NHMRC review (e.g. they did not investigate the treatment of health conditions in humans, they had already been considered in an earlier stage of the NHMRC review, or they were not published studies). The remaining 59 studies, which had not been included in the overview report, were assessed against pre-determined criteria for consideration. After this assessment, 17 more of these studies were excluded because they did not meet the criteria for the NHMRC review. Of the remaining 42 published studies, three represented a single study, resulting in a final total of 40 studies assessing the effectiveness of homeopathy for the treatment of health conditions, compared with no homeopathy or with other treatment. For each study, the risk of bias was systematically assessed using a standardised method (the Cochrane Collaboration’s tool for assessing risk of bias) and analysed. The included studies investigated homeopathy for the treatment of 14 health conditions (16 studies) that were covered by systematic reviews included in the overview: rheumatoid arthritis, influenza-like illness, hot flushes, rhinosinusitis, ankle sprain, oral dryness, psychophysiological-onset insomnia, stress, dermatological reactions to radiotherapy, warts, osteoarthritis of the knee, chronic low back pain, upper respiratory tract infection and otitis media. Most studies were assessed to have a moderate, moderate-to-high or high risk of bias. Many of these studies were poorly designed, poorly conducted or poorly reported. In addition, the studies had too few participants to be able to detect differences in health outcomes between the treatment groups. The findings of these studies did not alter the overall conclusions of the NHMRC review. Although one small study with a low risk of bias favoured homeopathy for the treatment of cough in upper respiratory tract infections, this study did not have enough participants to outweigh the wider body of evidence considered in the overview”.

“The OPTUM researchers searched databases of health publications to find systematic reviews published in English between 1 January 1997 and 3 January 2013. For each health condition, the research group collated the findings of the systematic reviews and assessed the quality and reliability of the evidence. The findings are described in detail in the Overview Report. The purpose of this approach was to use published systematic reviews as a way of identifying the body of evidence for homeopathic treatments. The professional research group did not accept the conclusions or interpretations of the systematic reviews, but instead considered the included studies. The professional research group evaluated the quality of each of the included studies using the information provided by the systematic reviews”.

Detailed assessments of NHMRC ‘Information Paper’ regarding effectiveness of of homeopathy in different classes of diseases are really amusing:
“There is no reliable evidence on which to draw a conclusion about the effectiveness of homeopathy, compared with placebo, for the treatment of these health conditions: acne vulgaris, acute otitis media (inflammation of the middle ear) in children, acute ankle sprain, acute trauma in orthopaedic patients, amoebiasis and giardiasis (gastrointestinal conditions caused by parasites), ankylosing spondylitis, boils and pyoderma (types of skin infections), Broca’s aphasia in people who have had a stroke, bronchitis, cholera, cough, chronic polyarthritis, dystocia (difficult labour), eczema, heroin addiction, knee joint haematoma (bruising), lower back pain, nausea and vomiting associated with chemotherapy, oral lichen planus, osteoarthritis, proctocolitis, postoperative pain-agitation syndrome, radiodermatitis (skin damage caused by radiotherapy) in women with breast cancer, seborrhoeic dermatitis, suppression of lactation after childbirth in women who elect not to breastfeed, stroke, traumatic brain injury (mild), uraemic pruritis, vein problems due to cannulas in people receiving chemotherapy.

Why NHMRC reached this conclusion? “For each condition, only one study that compared homeopathy with placebo was found, and this study was unreliable. It was either poor quality (poorly designed or poorly done) or unknown quality, or it had too few participants to give a meaningful result, or both”.

Don’t laugh, please! They could find only “one study”. That was “unreliable” also! Why should they wait to jump into their pre-determined ‘conclusion’?
NHMRC ‘paper’ continues: “There is no reliable evidence that homeopathy is as effective as the other therapies for the treatment of these health conditions- acute otitis media or otitis media with effusion (inflammation of the middle ear) in children (compared with antibiotics, mucolytic medicines, secretolytic medicines, antipyretic medicines, nasal sprays, or monitoring the condition but not providing treatment, allergic rhinitis (compared with antihistamines, cortisone or intranasal cromolyn sodium), anxiety or stress-related conditions (compared with lorazepam, diazepam or cognitive behavioural therapy), depression (compared with fluoxetine or diazepam) , eczema (compared with corticosteroids, antihistamines, or other unspecified therapies), non-allergic rhinitis (compared with aspirin, xylometazoline or other therapies), osteoarthritis (compared with paracetamol or various nonsteroidal anti-inflammatory drugs), upper respiratory tract infection (compared with anti-inflammatory drugs, antibiotics or other therapies).

“There is no reliable evidence on which to draw a conclusion about the effectiveness of homeopathy compared with other therapies for the treatment of these health conditions: burns (second- and third-degree), fibromyalgia, irritable bowel syndrome, malaria, proctocolitis (inflammation of the rectum and colon), recurrent vulvovaginal candidiasis (yeast infection of the vagina and/or vulva, also called ‘thrush’), rheumatoid arthritis”

Again, why NHMRC reached this conclusion? Their answer: “For each condition, only one study that compared homeopathy with another treatment was found, and this study was unreliable. It was either poor quality (poorly designed or poorly done) or unknown quality, or it had too few participants to give a meaningful result, or both.”

Do not miss this very important observation by NHMRC: “The studies of homeopathy were generally poor quality. For some health conditions, this meant that no conclusion could be made on whether or not homeopathy was effective. For other conditions, this meant that NHMRC could not be confident that the results reported by studies were reliable.”

If available studies of homeopathy were generally of “poor quality”, and “no conclusion could be made” on the basis of those studies, how could NHMRC come to the generalized conclusion that “homeopathy is ineffective”? If they “could not be confident” by available studies, how could be they so “confident” to give a sweeping verdict against homeopathy. NHMRC is bound to explain this point.

NHMRC admits the limitations of their study as follows:
“The overview was based on finding systematic reviews of homeopathy, rather than searching for all individual published studies of homeopathy. The advantage of this strategy was to make use of the large amount of work that had already been done by researchers around the world in finding and assessing studies and to provide an overarching picture of the whole body of evidence. However, there were also some disadvantages:

As the overview only included systematic reviews, some individual studies of homeopathy may not have been considered (particularly recent studies published since the latest systematic reviews). This risk was offset by inviting homeopathy interest groups and the public to provide extra evidence at two stages of the review: before the overview and at public consultation on the draft of this Information Paper. From this process an additional 42 studies were considered as part of the assessment of the evidence. These studies did not alter the overall findings of the assessment of the evidence.

To assess the quality of individual studies, the research group had to rely on the way that these were reported by systematic reviews. Details of study design (e.g. the outcomes measured and the length of follow up), the statistical significance of the results and the clinical importance of any reported health benefits were not always available. Also, the description of an individual study was sometimes inconsistent between systematic reviews. In these instances, the findings of the systematic review which was assessed to be of a higher quality was considered.
It was not possible to separate the evidence for clinical homeopathy (in which the homeopath chooses one or more homeopathic medicines to treat a particular health condition) and individualized homeopathy (in which the homeopath matches all the person’s symptoms to a single homeopathic medicine), because most of the systematic reviews did not analyze these separately. Most of the studies used clinical homeopathy.

It was not possible to make conclusions about the effects of homeopathy on each of the specific health outcomes (e.g. pain, mobility) relevant to a particular health condition (e.g. arthritis), because of the large number of outcomes and the different reporting of outcomes between the different systematic reviews. Instead, outcomes were aggregated for each health condition and a single conclusion made.

It was often difficult in studies to find the details of other treatments with which homeopathy was compared. To interpret the studies that compared homeopathy with another treatment, it is necessary to understand whether the other treatment is an effective standard treatment. This information was often not available from the systematic reviews.

It is also likely that some studies assessing homeopathic treatments have never been published. Searching of clinical trials registries can identify unpublished studies and enable researchers to obtain and analyze the results, but cannot identify studies that have not been registered. The overview identified only 10 systematic reviews that reported having considered publication bias, and only two of these made a comprehensive, systematic search for missing studies.”
One of these systematic reviews reported significant publication bias, which the authors suggested was primarily due to under-reporting of studies with statistically non-significant effects and with negative effects. Clinical trial registries (included the World Health Organisation Clinical Trials Registry, the US government’s ClinicalTrials.gov and the Australian New Zealand Clinical Trials Registry) were searched but did not identify any extra studies.
Despite the above limitations, it is unlikely that a review of primary studies (rather than of systematic reviews) would have altered the findings. This is because the studies on homeopathy identified through this process were generally small and of poor quality (either poorly designed or poorly done). Due to the poor quality of the evidence base, the Homeopathy Working Committee had to apply caution when considering the results reported by studies. For some health conditions, this meant that no conclusion could be made on whether or not homeopathy was effective. For other conditions, this meant that NHMRC could not be confident that the results reported by studies were reliable.”
Let us sum up an abstract of the “limitations” NHMRC themselves identified in their methodology:

As the overview only included systematic reviews, some individual studies of homeopathy may not have been considered.

To assess the quality of individual studies, the research group had to rely on the way that these were reported by systematic reviews.

It was not possible to separate the evidence for clinical homeopathy (in which the homeopath chooses one or more homeopathic medicines to treat a particular health condition) and individualized homeopathy (in which the homeopath matches all the person’s symptoms to a single homeopathic medicine).

It was not possible to make conclusions about the effects of homeopathy on each of the specific health outcomes.

It was often difficult in studies to find the details of other treatments with which homeopathy was compared.

It is also likely that some studies assessing homeopathic treatments have never been published.

For some health conditions, this meant that no conclusion could be made on whether or not homeopathy was effective. For other conditions, this meant that NHMRC could not be confident that the results reported by studies were reliable.”

All these are limitations of serious concern, which should have been properly attended and appropriately rectified before making any further “assessments” about homeopathy. Instead, NHMRC chose the comfort of ignoring these limitations by a sweeping remark: “Despite the above limitations, it is unlikely that a review of primary studies, rather than of systematic reviews would have altered the findings.”. They were so sure that nothing would alter their findings, as the ‘findings’ and ‘conclusions’ were pre-determined!

It is very much obvious that NHMRC report cannot be considered a sacred document that could be used as an authoritative evidence against homeopathy, as our sceptic friends falsely try to make it out. It is not an impartial document, but a clear cut and intentionally prepared anti homeopathy document!

Uterine Cervical Cancer is the most common cause of cancer, as well as the   most common cause of death from cancer in women around the world.   It was estimated that 528,000 cases of cervical cancer occurred, with 266,000 deaths in 2012 alone. This is about 8% of the total cases and total cancer deaths.  About 70% of cervical cancers occur in developing countries.  In low-income countries, it is the most common cause of cancer deaths.  In developed countries, the widespread use of cervical screening programs has dramatically reduced rates of cervical cancers.

Cervical cancer is a cancer arising from the uterine cervix.  It is due to the abnormal growth of cells that have the ability to invade or spread to other parts of the body. No symptoms are seen in earlier stages of disease process. Later symptoms may include abnormal vaginal bleeding, pelvic pain, or pain during sexual intercourse.  While bleeding after sex may not be serious, it may also indicate the presence of cervical cancer.

According to studies, Human papillomavirus (HPV) infection appears to be involved in the development of more than 90% of cases of cervical cancers. Sametime, it is also true that most people who have had HPV infections, however, do not develop cervical cancer.  Other risk factors include smoking, a weak immune system, birth control pills, starting sex at a young age, and having many sexual partners, but these are less important.  Cervical cancer typically develops from precancerous changes over 10 to 20 years.  About 90% of cervical cancer cases are squamous cell carcinomas, 10% are adenocarcinoma, and a small number are other types.  Diagnosis is typically by cervical screening followed by a biopsy.  Medical imaging is also done to determine whether or not the cancer has spread.

The early stages of cervical cancer may be completely free of symptoms.  Vaginal bleeding, contact bleeding (one most common form being bleeding after sexual intercourse), or (rarely) a vaginal mass may indicate the presence of malignancy. Also, moderate pain during sexual intercourse and vaginal discharge are symptoms of cervical cancer. In advanced disease, metastases may be present in the abdomen, lungs, or elsewhere.

Symptoms of advanced cervical cancer may include: loss of appetite, weight loss, fatigue, pelvic pain, back pain, leg pain, swollen legs, heavy vaginal bleeding, bone fractures, and/or (rarely) leakage of urine or feces from the vagina.  Bleeding after douching or after a pelvic exam is a common symptom of cervical cancer

Infection with HPV is generally believed to be required for cervical cancer to occur.  Genital warts, which are a form of benign tumor  of  epithelial  cells, are also caused by various strains of HPV. However, these serotypes are usually not related to cervical cancer. It is common to have multiple strains at the same time, including those that can cause cervical cancer along with those that cause warts.

Cigarette smoking, both active and passive, increases the risk of cervical cancer. Among HPV-infected women, current and former smokers have roughly two to three times the incidence of invasive cancer. Passive smoking is also associated with increased risk, but to a lesser extent.

Long-term use of oral contraceptives is associated with increased risk of cervical cancer. Women who have used oral contraceptives for 5 to 9 years have about three times the incidence of invasive cancer, and those who used them for 10 years or longer have about four times the risk.

Having many pregnancies is associated with an increased risk of cervical cancer. Among HPV-infected women, those who have had seven or more full-term pregnancies have around four times the risk of cancer compared with women with no pregnancies, and two to three times the risk of women who have had one or two full-term pregnancies.

HPV vaccines have been developed to protect against between two and seven high-risk strains of this family of viruses and may prevent up to 90% of cervical cancers.  As a risk of cancer still exists, guidelines recommend continuing regular Pap smears even after vaccinations. Other methods of prevention include: having few or no sexual partners and the use of condoms.  Cervical cancer screening using the Pap smear or acetic acid can identify precancerous changes which when treated can prevent the development of cancer. Modern treatment of cervical cancer may consist of some combination of surgery, chemotherapy, and radiotherapy.   Five year survival rates in the United States by these treatment protocols are 68%.  Outcomes, however, depend very much on how early the cancer is detected.

Preventive vaccines are currently developed to protect against the two HPV types (16 and 18) that cause about 70% of cervical cancers worldwide. Vaccines that protect against more of the types common in cancers are expected to prevent more cancers.  For instance, a vaccine against the seven types most common in cervical cancers (16, 18, 45, 31, 33, 52, 58) is estimated to prevent 87% of cervical cancers worldwide.

HPV types 16, 18 and 45 contribute to 94% of cervical adenocarcinoma  (cancers originating in the glandular cells of the cervix). While most cervical cancer arises in the squamous cells, adenocarcinomas make up a sizable minority of cancers.  Further, Pap smears are not as effective at detecting adenocarcinomas, so where Pap screening programs are in place, a larger proportion of the remaining cancers are adenocarcinomas.

HPV vaccine ‘Gardasil’ contains inactive L1 proteins from four different HPV strains: 6, 11, 16, and 18.  Together, these HPV types 16 and 18 currently cause about 70 percent of all cervical cancer, and about 90 percent of all cases of genital warts. HPV types 6 and 11  are much less likely to cause cancer, but do cause genital warts.

Only a small percentage of women with cervical cancer in the developing world get diagnosed and treated in early stages.  Most cases are identified only after reaching an incurable stage.  HPV vaccinations may be effective to certain extent, but its cost is very high, making mass vaccination programs unaffordable to poor countries.

Currently the HPV vaccine is not recommended for pregnant women.  There have been reports of death in females after receiving the vaccine, even though such deaths were not linked to the vaccine beyond doubts. Additionally, there have been rare reports of blood clots forming in the heart, lungs and legs after getting vaccinated. There have been 22,000 Vaccine Adverse Event Reporting System (VAERS) reports following the HPV vaccination in US alone, even though ninety-two percent were reports of events considered to be non-serious (e.g., fainting, pain and swelling at the injection site (arm), headache, nausea and fever). But 9 percent were considered to be serious (death, permanent disability, life-threatening illness and hospitalization).

The long-term effects of the vaccine on fertility are not known, but no effects are anticipated. Even though FDA has classified the HPV vaccine as a pregnancy Category B, meaning there is no apparent harm on the fetus in animal studies, and HPV vaccines have not been causally related with adverse pregnancy outcomes or adverse effects on the fetus, data on vaccination during pregnancy is very limited.  It has been advised that vaccination during the pregnancy term should be delayed until more information is available. If a woman is found to be pregnant during the three dose series of vaccination, the series will be postponed until pregnancy has been completed.

Risk of long term adverse effects of HPV vaccines also cannot be ignored.  Antibodies generated in the body in response to vaccinations may remain as ‘miasms’ for long periods, causing ‘off-target’ molecular inhibitions that may produce diverse kinds of chronic disease dispositions. In this circumstance, we have to think about more scientific, safe and cost-effective alternative ways for preventing and treating cervical cancers in the society.

It is very important to note that currently available HPV vaccines do not treat existing HPV infection or cervical cancer. HPV vaccines are used only to prevent HPV infection and therefore cervical cancer. They are recommended for women who are 9 to 25 years old who have not been exposed to HPV. However, since it is very unlikely that a woman will have already contracted all four viruses, since  HPV is primarily sexually transmitted.

Here comes the relevance of MIT approach to cervical cancers, considering the risks and limitations of HPV vaccines. Molecular Imprints of viral proteins of multiple strains of Human Papilloma Virus could be produced and used as prophylactic as well as therapeutic agents against this disease.

The HPV vaccines are based on hollow virus-like particles (VLPs) assembled from recombinant HPV coat proteins. The virus possesses circular double stranded DNA and a viral shell that is composed of 72 capsomeres. Every subunit of the virus is composed of two proteins molecules, L1 and L2. The reason why this virus has the capability to affect the skin and the mucous layers is due to its structure. The primary structures expressed in these areas are E1 and E2, these proteins are responsible for the replication of the virus. E1 is a highly conserved protein in the virus, E1 is in charge of the production of viral copies is also involved in every step of replication process. The second component of this process is E2 ensures that non-specific interaction occur while interacting with E1.  As a result of these proteins working together is assures that numerous amounts of copies are made within the host cell. The structure of the virus is critical because this influence the infection affinity of the virus. Knowing the structure of the virus allowed for the development of HPV vaccines.

Molecular Imprints could be prepared in a ‘water-alcohol’ matrix from these ‘hpv coat proteins’, especially L1 and L2 proteins which constitute every subunit of the HPV virus, by the process of homeopathic potentization.  These molecular imprints will have conformations exactly opposite to the conformations of functional groups of L1 and L2 proteins. Due to this complementary conformations, these molecular imprints can act as ‘artificial binding sites’ for viral proteins, thereby preventing their interactions with biological molecules in human body. By this bio-molecular mechanism, HPV infection is prevented, and disease processes in already infected persons reversed.

According to MIT perspective, it is obvious from the above discussions that ‘L1 proteins’ extracted from four different HPV strains (6, 11, 16, and 18) and potentized above 12c will be the ideal homeopathic drug for prevention and treatment of  UTERINE CERVICAL CANCERS caused by Human Papilloma Viruses.

Of course, MEDORRHINUM 12C or 30C will play a major role in MIT protocol for cervical cancer treatment, since this homeopathic nosode is prepared from disease products containing a combination of infectious agents of gonorrhea as well as ‘figwart disease’ or human papilloma virus disease. MEDORRHINUM in potentized form will most probably contain molecular imprints of ‘hpv coat proteins’.  CARCINOCIN 30 also should be included, as it will contain molecular imprints capable of deactivating various chemical molecules synthesized by cancer cells

Homeopathic constitutional SIMILIMUM selected on the basis of mental symptoms and physical generals also should be included in this treatment protocol in potencies above 12C for a complete cure.

Polycystic ovary syndrome (PCOS) is a term used to describe a set of symptoms expressed in a large percentage of women visiting doctors with various gynecological problems, which arise from hormonal imbalances. The name PCOD is used when there is ultrasonographic evidences for ovarian cysts. PCOS is the most common endocrine disorder among women between the ages of 18 and 44. It affects approximately 5% to 10% of this age group. It is one of the leading causes of poor fertility.

Signs and symptoms of PCOS include irregular or no menstrual periods, heavy periods, excess growth of body and facial hair, acne, pelvic pain, infertility due to anovulation, and patches of thick, darker, velvety skin. PCOS commonly appear associated with conditions such as type 2 diabetes, obesity, obstructive sleep apnoea, heart disease, mood disorders, and endometrial cancer.

PCOS is considered to be caused by a combination of genetic as well as environmental factors. Obesity, lack of physical exercise, and a family history of someone with such conditions are major risk factors. Diagnosis is mainly based on two of the following three findings- no ovulation, high androgen levels, and ovarian cysts detectable by ultrasound scanning. Differential diagnosis is required to rule out other conditions that produce similar symptoms, which include adrenal hyperplasia, hypothyroidism, and hyperprolactinemia.They try to alleviate symptoms by  lifestyle changes such as weight loss and exercises, and administration of ‘birth control pills’ to  regularize  menstrual  periods. Anti-androgenic drugs are used in certain cases. Various drugs and techniques are used to treat acne and to control excess hair growth.  Efforts to improve fertility include reducing weight, administering drugs, and in vitro fertilization.

Major signs and symptoms of PCOS include   menstrual disorders such as ooligomenorrhoea (few menstrual periods) or amenorrhea (no menstrual periods) and  infertility resulting from lack of ovulation.  Other common signs are acne and hirsutism (male pattern of hair growth). There may be heavy and prolonged menstrual periods in some cases. Androgenic alopecia with hair thinning or diffuse hair loss may also appear in certain individuals. Levels of androgens or male sex hormones are found to be raised in PCOS patients. There appears as a tendency towards central obesity and other symptoms associated with insulin resistance.  Serum insulin levels, insulin resistance, and homocysteine levels are higher in women with PCOS.

There is strong evidence that PCOS is a genetic disease.  The genetic component appears to be inherited in an autosomal dominant fashion with high genetic penetrance but variable expressivity in females; this means that each child has a 50% chance of inheriting the predisposing genetic variant from a parent, and, if a daughter receives the variant, the daughter will have the disease to some extent. The genetic variants can be inherited from either the father or the mother, and can be passed along to both sons daughters. Sons  may be asymptomatic carriers or may have symptoms such as early baldness.  and daughters show the signs of PCOS. In rare instances, single-gene mutations can give rise to the phenotype of the syndrome. Current  understanding of the pathogenesis of the syndrome suggests, however, that it is a complex multigenic disorder.

Obesity seems to play a big role in determining the severity of PCOS symptoms. PCOS has some aspects of a metabolic disorder, and its symptoms are partly reversible. Even though the name suggests that the ovaries are central to disease pathology, cysts are a symptom instead of the cause of the disease. Some symptoms of PCOS will persist even if both ovaries are removed; the disease can appear even if cysts are absent.. Gynecologists often see it as a gynecological problem, with the ovaries being the primary organ affected. However, recent insights show a multisystem disorder, with the primary problem lying in hormonal regulation in the hypothalamus, with the involvement of many organs. The term PCOS is used since there is a wide spectrum of symptoms possible, and cysts in the ovaries are seen only in 15% of people affected with the syndrome.

PCOS may be related to or worsened by exposures to certain drugs during the prenatal period, epigenetic factors, environmental impacts such as  industrial endocrine disruptors.

History-taking, specifically for menstrual pattern, obesity, hirsutism and acne is very important for diagnosing PCOS. Gynecologic ultrasonography, specifically looking for small ovarian follicles is also important. These ‘cysts’ are believed to be the result of disturbed ovarian function with failed ovulation, reflected by the infrequent or absent menstruation that is typical of the condition. Determining whether an elevation of the serum levels of androgens including androstenedione and testosterone is necessary for diagnosis. The free testosterone level is thought to be the best measure, with more than 60% of PCOS patients demonstrating supranormal levels. Glucose tolerance tests as well as testing fasting insulin levels are also necessary. Other causes of irregular or absent menstruation and hirsutism, such as hypothyroidism, congenital adrenal hyperplasia (21-hydroxylase deficiency), Cushing’s syndrome, hyperprolactinemia, androgen secreting neoplasms, and other pituitary or adrenal disorders, should be investigated and ruled out.

Polycystic ovaries develop when the ovaries are stimulated to produce excessive amounts of male hormones (androgens), in particular testosterone, by either one or a combination of the following (almost certainly combined with genetic susceptibility-  the release of excessive luteinizing hormone (LH) by the anterior pituitary gland, and through high levels of insulin in the blood in women whose ovaries are sensitive to this stimulus.

A majority of people with PCOS have insulin resistance and/or are obese. Their elevated insulin levels contribute to or cause the abnormalities seen in the hypothalamic-pituitary-ovarian axis that lead to PCOS. Hyperinsulinemia increases GnRH pulse frequency, LH over FSH dominance, increased ovarian androgen production, decreased follicular maturation, and decreased SHBG binding; all these steps contribute to the development of PCOS. Insulin resistance is a common finding among women with a normal weight as well as overweight women.

Adipose tissue possesses aromatase, an enzyme that converts androstenedione to estrone and testosterone to estradiol. The excess of adipose tissue in obese women creates the paradox of having both excess androgens which are responsible for hirsutism and virilization, and estrogens which inhibits FSH via negative feedback.

PCOS may be associated with chronic inflammation, with several investigators correlating inflammatory mediators with anovulation and other PCOS symptoms.  Similarly, there seems to be a relation between PCOS and increased level of oxidative stress.

According to MIT perspective, INSULIN 30 is the main homeopathic drug for treating PCOS, as the molecular imprints contained in that drug can reverse the harmful biochemical processes caused by hyperinsulinemia and insulin resistance, which is the starting point of all abnormalities in hypothalamic-pituitary-ovarian axis that lead to PCOS. Drug will have to be repeated twice every day, and continued for a long period.   Since PCOS is a metabolic syndrome involved with abnormalities in diverse hormonal pathways, PITUTRIN 30, ACTH 30, TESTOSTERONE 30 and THYROIDINUM 30 also should be administered in combination or alternation with INSULIN 30.

Better and faster results are produced if we include in this protocol  the homeopathic ‘constitutional’ similimum worked out on the basis of physical generals and mental symptoms expressed by the patient.

Indications of positive response to this highly scientific treatment protocol are observable by three months, as menstrual periods become regular, and male pattern hair growth begins to fade away. All symptoms gradually disappear within 6-12 months of starting medication. Homeopaths can confidently try this method, since there  are absolutely no chances for any kind of adverse effects from using drugs potentized above Avogadro limit.

I want to make it clear from the very beginning that I do not have any personal contact with the people working behind ‘Banerji Protocols’, or any kind of business interest in their ‘method’. We are absolute strangers. Whatever information I have about them and their method were collected from their websites as well as interactions with their followers who practice it. Actually, I have my own reservations and disagreements regarding the business strategy adopted by them. I would have been happier, if they made their valuable experience and knowledge freely available to the homeopathic community in the common interests of homeopathy, instead of promoting it merely as a private ‘commodity’ targeted for the market.

In spite of my above mentioned reservations, I hereby declare that I am whole heartedly supporting and recommending ‘banerji protocols’ as a rational and simplified method of practicing ‘using’ homeopathic drugs.  My support comes not from any material interest, but from my theoretical convictions that evolved from studying ‘banerji protocols’ in the light of   MIT concepts of scientific homeopathy.

The ‘Banerji Protocols’ developed and promoted by Dr. Prasanta Banerji Homoeopathic Research Foundation, Kolkota (PBHRF),  is a new method of treatment using homeopathic medicines recently becoming very popular among homeopaths all over the world due to its effectiveness and simplicity . According to this method, ‘specific’ medicines are prescribed for ‘specific’ diseases. Diseases are diagnosed using modern state of the art methods and tools. According to their view, modern diagnostic approaches incorporate and help in the selection of medicines so that ‘specific’ medicines could be easily prescribed for ‘specific’ diseases. This approach differs from classical homeopathy, where prescriptions are expected to be made on the basis of ‘totality of symptoms’, ‘mental symptoms’, ‘physical generals’, ‘constitutions’  and ‘miasmatic analysis’, giving least importance to diagnostic aspects.

This approach of prescribing ‘specific’ homeopathic medicines for a ‘specific’ disease, based on ‘diagnosis as well as symptoms’ is the mainstay of ‘Banerji Protocols’. On the basis of huge clinical experiences of three generations of homeopaths belonging to Banerji family, they have prepared elaborate treatment protocols for all the important diseases by preparing lists of  homeopathic ‘specifics’ based on diagnosis. Final selection of medicine for a particular patient is made from these ‘lists of specifics’, after considering the individual ‘symptomatology’ also. As such, ‘banerji protocols’ is a combination of ‘specifcs’ and ‘symptomatology’ approaches. With the passage of time and the availability of new diagnostic tools like ultrasonography, MRIs, cancer markers and other advanced tests, original treatment protocols were streamlined accordingly. PBHRF sources claim that the efficiency of this streamlining is reflected by the encouraging results of The Banerji Protocols.

In The ‘Banerji Protocols’ of treatment, mixtures of potentized remedies as well as frequent repetitions of the remedies are allowed to be freely used when required, which is never allowed or  practiced in classical homeopathy. This is a big departure from classical homeopathic approach, where ‘single drug-single dose’ concept is considered as an important ‘fundamental principle’. Banerji claims that the strategy of combination of potentized medicines is  based on years of ‘clinical experiments’ and ‘observations’ conducted at  PBHRF. According to their view, ‘mixing’ of drugs  have special advantages in treatment, so that the “aggravation due to drugs can be checked, side effects of the medicines can be abated, quick and uneventful recovery can be ensured in a much shorter time”.

In Banerji Protocols, specific homeopathic medicines are also used for supportive care. Homeopathic medicines prescribed on constitutional grounds are also used in supportive and palliative treatments for patients with malignant disease. It is obvious that this method is very flexible one, without the burdens of complex ‘principles’, ‘laws’ and ‘theories’. The Banerji Protocols of Treatment is claimed by its proponents to be scientific, logical and based on all modern diagnostic tools and is very realistic.

A very important point to be noted in this regard is that the proponents of ‘banerji protocols’ do not make tall scholarly claims about their ‘method’, or construct speculative ‘theories’ to justify their method. Being a ‘practice-oriented’ method, evolved from ‘practical experience, they do not try to answer the fundamental questions such as ‘what are the active principles of potentized drugs’ or ‘what is the biological mechanism of homeopathic cure’.  They frankly admit that their method is “based on years of clinical experiments and observations” only. Their method is practice-oriented and result-oriented. Nothing more, nothing less. There lies the strength and weakness of ‘banerji protocols’.

Viewing from MIT perspective, I am happy to say that ‘banerji protocols’ is fully endorsed by scientific knowledge of homeopathy, even though they are not bothered about such a theoretical endorsement.

Classical homeopaths raise objections against ‘banerji protocols’ on various points, accusing that the ‘protocols’ go against all ‘fundamental laws and principles’ taught by ‘masters’ and ‘stalwarts’. Their main objections are regarding the method of prescribing on the basis of ‘pathology and diagnosis’, defying the classical principle of ‘similia similibus curentur’. Another objection is that by using ‘multiple drugs’ and ‘frequent repetitions’, banerji protocol contravenes the principles of ‘single drug’ and ‘single dose’. ‘Mixing’, ‘combinations’ and ‘alternations’ of remedies are also considered to be contradicting the ‘fundamental laws’ of homeopathy. Other grave accusations are  that banerji protocol ignores the concepts of ‘homeopathic aggravations’, ‘drug relationships’, ‘suppressions’, ‘theory of miasms’, ‘constitutions’ and ‘directions of cure’.

Even though the proponents of banerji protocols are least bothered about these accusations leveled against them, concentrating only on ‘results’ and ‘cures’, I think MIT concepts have already answered them in most rational and scientific terms.  Understanding  the scientific explanations of homeopathy proposed by MIT will enable homeopaths to learn, explain and apply ‘banerji protocols’ more rationally, scientifically and effectively

What is MIT?

MIT or Molecular Imprints Therapeutics refers to a scientific hypothesis that proposes a rational model for biological mechanism of homeopathic therapeutics.

According to MIT hypothesis, potentization involves a process of ‘molecular imprinting’, where in the conformational details of individual drug molecules are ‘imprinted’ or engraved as hydrogen-bonded three dimensional nano-cavities into a supra-molecular matrix of water and ethyl alcohol, through a process of molecular level ‘host-guest’ interactions. These ‘molecular imprints’ or ‘hydrosomes’ are the active principles of post-avogadro dilutions used as homeopathic drugs.

Due to ‘conformational affinity’, molecular imprints can act as ‘artificial key holes’ or ‘ligand binds’ for the specific drug molecules used for imprinting, and for all pathogenic molecules having functional groups ‘similar’ to those drug molecules. When used as therapeutic agents, molecular imprints selectively bind to the pathogenic molecules having conformational affinity and deactivate them, thereby relieving the biological molecules from the inhibitions or blocks caused by pathogenic molecules. According to MIT hypothesis, this is the biological mechanism of high dilution therapeutics involved in homeopathic cure.

According to MIT hypothesis, ‘Similia Similibus Curentur’ means, diseases expressed through a particular group of symptoms could be cured by ‘molecular imprints’ forms of drug substances, which in ‘molecular’ or crude forms could produce ‘similar’ groups of symptoms in healthy individuals. ‘Similarity’ of drug symptoms and diseaes indicates ‘similarity’ of pathological molecular inhibitions caused by drug molecules and pathogenic molecules, which in turn indicates conformational ‘similarity’ of functional groups of drug molecules and pathogenic molecules. Since molecular imprints of ‘similar’ molecules can bind to ‘similar’ ligand molecules by conformational affinity, they can act as therapeutic agents when applied as indicated by ‘similarity of symptoms’.

No body in the whole history could so far propose a hypothesis about homeopathy as scientific, rational and perfect as MIT, explaining the molecular process involed in potentization, and the biological mechanism involved in ‘similia similibus curentur’, in a way fitting well to modern scientific knowledge system.

‘Single drug/multiple drug’ issue:

When you understand MIT, and start perceiving potentized drugs in terms of diverse types of ‘molecular imprints’ as the ‘active principles’ they contain, you will realize that all controversies over ‘single/multiple’ drug  issue leveled against ‘Banerji protocols become totally irrelevant.

According to MIT view, ‘similimum’ essentially means a drug substance that can provide the specific molecular imprints required to remove the particular molecular errors that caused the particular disease condition in the particular patient. Whatever be the ‘method’ by which the drug is selected, similimum is a similimum if it serves the purpose of curing the patient when administered in potentized form.

Since ‘multiple’ molecular errors exist in any patient in a particular point of time, expressed through ‘multiple’ groups of symptoms, he will inevitably need ‘multiple’ molecular imprints to remove them. If potentized form of a ‘single’ medicinal substance can provide all those ‘multiple’ molecular imprints, that ‘single’ drug substance will be enough. If we could not find a ‘single’ drug substance that contain ‘all’ the ‘multiple’ molecular imprints required by the patient as indicated by the ‘symptom groups’, we will have to include ‘multiple’ drug substances in our prescription. It is the constituent molecular imprints contained in our particular prescription that matter.

Important point is, we have to ensure that our prescription supplies all the diverse types of molecular imprints required for deactivating all the diverse types of pathogenic molecules existing in the patient, as indicated by the diverse groups of subjective and objective symptoms expressed by him. If we could find a single drug preparation that could supply all the molecular imprints required by the patient I am dealing with, we can use that single drug preparation only. If we do not find such a single drug, we have to include as many number of drug preparations as required, in order to provide all the molecular imprints needed to remove all the molecular errors in the patient.

‘Single/multiple’ drug controversy never bothers one who understands this scientific approach proposed by MIT, as we start thinking in terms of molecular imprints- not in terms of drug names. Actually, a drug becomes ‘single’,  if it contains ‘single’ type of molecular imprints only. IF a drug contains more than one type of molecular imprints,  it is a compound drug, even if it is known by a ‘single’ drug name, prepared from a ‘single’ source material, kept in a ‘single’ bottle, consumed as a ‘single’ unit for ‘drug proving’, or considered by ‘masters’ as ‘single’ drug.

When we consume a complex drug substance in crude form, it is absorbed into the blood as various individual chemical molecules contained in it. It is these individual chemical molecules that interact with various biological molecules. Different molecules act up on different biological targets according to the molecular affinities of their functional groups. Biological molecules are inhibited, resulting in errors in the biochemical pathways mediated by those biological molecules. Such molecular level errors in biological processes cascades into a series of molecular errors, which are expressed through various groups of subjective and objective symptoms.

It is obvious that what we consider as the symptoms of that drug substance  are actually the sum total of different symptom groups, representing entirely different molecular errors produced in entirely different biological molecules, by the actions of entirely different chemical molecules contained in the crude drug.

We have to remember, there is no such a thing called nux vomica molecule or pulsatilla molecule- only individual chemical molecules contained in nux vomica or pulsatilla tinctures. Each constituent molecule has its own specific chemical structure and properties. They act on different biological targets by their chemical properties.

Each individual chemical molecule contained in a complex crude drug substance acts as an individual drug. That means, nux vomica or pulsatilla are not single drugs as we are taught, but  compound drugs.      Classical homeopaths may find it difficult to accept this fact, as it contradicts with their beliefs as well as the lessons they are taught. But it is the scientific fact.

From scientific point of view of pharmaceutical chemistry, a drug is a biologically active unit contained in a substance used as therapeutic agent. It is the structure and properties of that chemical molecule that decides its medicinal properties and therapeutic actions. if such as substance contains only one type of biologically active unit, it is a single drug. If it contains different types of biologically active units, it is a compound drug.  It is obvious that most of the drugs we use in homeopathy – especially drugs of biological origin and complex minerals- contain diverse types of biologically active units, and hence they cannot be considered single drugs.

Molecular imprinting happens as individual molecules, and as such, potentized drugs prepared from a single drug substance will contain diverse types of molecular imprints representing the diverse types of individual constituent molecules contained in the substance. Those molecular imprints also act as individual units when applied in the organism. Hence, potentized drugs prepared by using a complex, seemingly single drug substance is actually a compound drug, containing diverse types of biologically active units, or  ‘molecular imprints’.

Issue of ‘frequent repetition of doses’:

Another objection raised by classical homeopaths against ‘Banerji protocols’ is regarding frequent repetition of doses. “Single dose and wait” is considered by many homeopaths to be the golden law of homeopathic prescription. According to them, repetition of doses at frequent intervals is said to be harmful.

MIT differs with Classical Homeopathy on this point also. I think many a excellent homeopathic prescriptions are spoiled only due to our ‘theoretical’ hesitation to repeat the doses in adequate intervals, and these failures are wrongly attributed to  ‘wrong selection of similimum’ or ‘wrong selection of potency’. We could have avoided such failures by repeating the doses frequently so as to maintain the drug action at optimum levels to produce  a complete cure.

My concepts regarding ‘repetitions’ come from the scientific understanding of potentization as ‘molecular imprinting’ and the active principles of potentized medicines as ‘molecular imprints’ of constituent drug molecules used for potentization. You cannot follow me without understanding the concept of ‘molecular imprints’.

‘Molecular imprints’ contained in potentized drugs act by binding to the pathological molecules having ‘complementary’ configuration, thereby relieving biological molecules from pathological inhibitions. Same time, these ‘molecular imprints’ could be anti-doted or deactivated by  molecules or ions having complementary configurations. That means, ‘molecular imprints’ we introduce  into the body get deactivated by pathological molecules or other molecules having configurational affinity. Molecules and ions of vegetable alkaloids, enzymes, food additives, environmental toxins, infectious agents, bacterial-viral toxins and a host of other agents may antidote these ‘molecular imprints’. Hence, it is necessary to replenish the supply of ‘molecular imprints’ at frequent intervals to ensure a complete cure. That is my point in favour of frequent repetitions.

Homeopathic ‘aggravations’:

Classical homeopaths accuse that ‘banerji protocols’ do not address the issue of homeopathic aggravations properly. MIT has well studied rational explanations about the phenomenon known as ‘homeopathic aggravation’ also.  It is true that in many instances we experience such aggravation of symptoms after prescribing homeopathic medicines. Some homeopaths believe that aggravations occur due to wrong prescriptions, whereas some others consider it happening as part of curative process due to ‘exact’ prescriptions. Some homeopaths also try to differentiate between ‘medicinal’ aggravations which are harmful, and ‘homeopathic’ aggravations which are welcome.

As per MIT view, such ‘aggravations’ are not due to ‘prescribing wrong drugs’ or ‘exact drugs’, but due to prescribing drugs that cover only part of the ‘symptom complexes’ present in the patient. To follow what I say, one should be well aware of the concepts of ‘molecular errors’ underlying pathology, as well as ‘molecular imprints’ present in potentized medicines. As per our view, an individual will be having multitudes of ‘molecular errors’ caused by binding of diverse types of pathogenic molecules on different biological molecules. Each individual ‘molecular error’ may be expressed in the form of specific subjective and objective ‘symptom complexes’. If we select a drug as a similimum on the basis of some of the leading symptoms only, ignoring other symptoms, that similimum in fact covers only some of the molecular errors. The ‘molecular imprints’ contained in that similimum may remove those molecular errors only. But other molecular errors remain. The ‘symptom complexes’ representing those remaining molecular errors would become more expressive and come to the fore. In the absence of scientific understanding regarding the molecular processes behind this phenomenon, we happen to interpret these new expressions as ‘homeopathic aggravation’.

Most of us would have experienced some initial aggravations followed by complete relief. We should perceive ‘molecular errors’ not as singular or static events. A particular molecular error caused by a particular pathogenic molecule may result in cascading of new molecular errors. It is like a traffic block in a city. A small traffic block may cause cascading of traffic blocks, ultimately resulting in total failure of traffic system in the city. When a molecular error occurs in a particular biochemical pathway in the organism, it may affect other related pathways also. That is why diseases progress expressing trains of new symptoms. When we start removing these molecular blocks, there may be readjustments happening in all these related biochemical pathways, which may appear as aggravations of symptoms. That is part of normal curative process.

That means, when studying the phenomena of ‘homeopathic aggravations”, both chances will have to be considered; “re-adjustments’ happening in various biochemical pathways as part of curative process, as well as ‘appearing of residual symptoms’ because of prescription being partial.

When we follow the total cure method proposed by MIT, we prescribe a combination of drugs that would contain all the ‘molecular imprints’ required to rectify all the ‘molecular errors’ covering all ‘symptom complexes’ expressed by the individual. Hence, so-called ‘homeopathic aggravations’ are never experienced in total cure prescriptions.

Homeopathic case follow up consists of watching for residual symptoms and emerging symptoms, and re-adjusting prescriptions as indicated by them. After making a homeopathic prescription, whether it be ‘single’ or ‘multiple’, and ensuring that the doses are used in right potencies and repeated in optimum frequencies, the physician should see the patient at reasonable intervals and carefully watch how the case is progressing.

MIT advises to periodically watch for ‘residual’ symptoms that do not subside, as well as newly ’emerging’ symptoms. If a particular ‘group of symptoms’ remain in spite of frequent repetitions of doses for a reasonable period, that means our prescription failed to provide the particular ‘molecular imprints’ required to remove the molecular inhibitions underlying that particular ‘group of symptoms’. Repertorise using those ‘residual’ symptoms, find a similimum for them, and add it to the original prescription.

If new symptoms ’emerge’, and they are not subsiding within a reasonable period, that means some ‘hidden’ molecular inhibitions not covered by the original prescription has come to the forefront during the removal of some other molecular errors. Find a new similimum for these newly emerged symptoms and add it to the original prescription. We will have to continue this constant watch for ‘residual’ symptoms and ’emerging’ symptoms and adjust prescriptions all through the whole course of treatment, in order to ensure a total cure.

Please note, observation of ‘banerji protocols’ that “mixing of drugs  have special advantages in treatment, so that the aggravation due to drugs can be checked, side effects of the medicines can be abated, quick and uneventful recovery can be ensured in a much shorter time” fully agree with the theoretical stand taken by MIT concepts on this issue.

Concept of ‘complementary prescriptions’:

According to MIT view, a ‘single drug’ being 100% similimum for a patient is almost like an utopian concept. Nobody can find a drug that is 100% similimum for a given case. We can find only a ‘most appropriate’ similimum. Hence, offering ‘total cure’ for a patient with ‘single’ drug is practically impossible, whatever the claims are.

An individual will be having diverse types of ‘molecular errors’ in him, with diverse types of pathological conditions, expressed through different groups of subjective and objective symptoms. These molecular errors may belong to genetic, miasmatic, environmental, infectious, emotional, nutritional or such diverse causative factors.

When we match the symptom picture of a given patient with symptom picture of drugs in our material medica to determine a similimum, we are actually matching individual molecular errors in the organism with individual drug molecules contained in the drugs. A drug that contains maximum types of ‘molecular imprints’ matching to maximum types of molecular errors in the organism is considered to be ‘most appropriate ‘similimum. No drug would contain ‘all’ the molecular imprints required to rectify ‘all’ the molecular errors existing in a given patient. Hence, any similimum we select would be only a ‘partial’ similimum for the patient. As such, a ‘single’ drug can never ‘cure’ a patient in his ‘totality’.  The similimum we selected would remove only the molecular errors matching to the molecular imprints contained in it, and hence, it would offer only partial cure.

For a ‘total’ cure, we will have to select additional drugs that would contain molecular imprints matching to the remaining molecular errors, which could be selected on the basis of symptoms that are not covered by the first similimum.

Here comes the relevance of the concept of ‘complementary’ prescriptions, especially if the physician is averse to using multiple drugs in a ‘single’ prescription. The concept of ‘complementary prescriptions’ should not be confused with the concept of ‘complementary drugs’. Concept of ‘complementary drugs’ is based on the arbitrary theory that such and such drugs are ‘complementary’ to such and such drugs. It is not based on study of similarity of symptoms. But the concept of ‘complementary prescription’ is based on the real study of symptoms in the patient that are not covered by the similimum selected as the first prescription.

In my opinion, the existing concept of ‘complementary drugs’ should be replaced with a new concept of ‘complementary prescriptions’, which seems to be more scientific and logical.

There is no need of any kind of restrictions for the number of ‘complementary prescriptions’. If the first ‘complementary prescription’ is not enough to complete the cure, we can look for a second ‘complementary prescription’ on the basis of remaining symptoms. We can ensure ‘total cure’ for the patient through systematic application of this ‘complementary prescritption’ method. Whether the ‘complementary prescriptions’ are applied along with or after the first prescription, could be decided by the physician according to his perceptions.

‘Banerji protocols’ also utilize the strategy ‘complementary prescriptions’, even though without any theoretical explanation or justification as MIT do. But in this case also, their ‘experience-based’ approach is rational and very close to that of MIT.

‘Combinations’ of potentized drugs:

Another serious objection against ‘banerji protocols’ from the side of classical homeopaths is regarding ‘mixing’ or ‘combinations’ of potentized drugs. On the other hand, MIT says that it is permissible  for to use combinations of ‘molecular imprinted’ forms (potencies above Avogadro limit- 12c and onwards) of two or more homeopathic drugs selected on the basis of analysis of totality of symptoms, miasmatic study and biochemical evaluation of the individual patient.

MIT view is that  it is effective as palliatives to use ‘disease-specific’ combinations of ‘molecular imprinted’ forms (potencies above Avogadro limit- 12c and onwards) of two or more homeopathic drugs selected on the basis of common symptoms and biochemical evaluations of specific diseases. But such ‘disease-specific’ combinations will not offer ‘total cure’ for patients, without incorporating drugs selected on the basis of symptoms also. This approach also is very close to the method of ‘banerji protocols’ that makes ‘specific’ prescriptions based on ‘disease diagnosis’ as well as symptomatology..

I am talking on the basis of my concepts of ‘molecular imprinting’ involved in potentization. I perceive all crude drugs as combinations of diverse types of constituent drug molecules. I perceive even the so called potentized ‘single’ drug as combinations of diverse types of individual drug molecules contained in the drug substance used for potentization.

My stand on this issue is based on my understanding of diseases as multitudes of pathological derangement in the organism, caused by diverse of types of molecular inhibitions caused by different types of pathogenic agents, and therapeutics involves the removal of those inhibitions using appropriate molecular imprints.

I am talking on the basis of my understanding of ‘similia similibus curentur’ as: “Pathological molecular inhibitions caused by specific pathogenic molecules and expressed through a certain group of subjective and objective symptoms, could be removed by applying ‘molecular imprints’ of drug molecules that could create similar molecular inhibitions and symptoms in a healthy organism when applied in crude form.

That makes the difference between my views and classical homeopathy. I know, homeopaths trained and experienced in classical homeopathy cannot agree with my views on this topic.

Role of ‘Diagnosis’ in making homeopathic prescriptions:

‘Banerji Protocols’ is based on specifics determined on the basis of ‘diagnosis’, and as such, they give utmost importance to diagnostic techniques and tools. Since homeopathy is practiced on the basis of therapeutic principle of ‘Similia Similibus Curentu’, many homeopaths think that clinical diagnosis has no place in homeopathic practice.They consider these factors only of lesser value, helpful only for ‘patient satisfaction’ or ‘prognosis’.

MIT says that  we should perceive the information provided by modern technological advancements and laboratory investigations as part of collecting ‘objective’ symptoms, and learn to utilize them in the search for similimum.

All diagnostic tools provided by ‘modern technology’ are only extensions of physician’s sense organs, which help in making ‘enhanced’ observation of his patient’s symptoms. Similar to the ordinary spectacle that enhances the vision or stethoscope enhances the sounds, laboratory tests and sophisticated equipments ‘enhances’ our observation. As such, information provided by these tests and tools should be considered as ‘Objective Symptoms’ similar to any other objective symptoms, and can be utilized in finding similimum. Only problem is, since our drug provings were not conducted insuch a technologically advanced environment, they do not provide these types of ‘enhanced symptoms’. Due to ill-equipped drug- provings so far conducted, we have no a systematic knowledge of such symptoms now available in our materia medica. But, we can collect such clinical observations from daily practice, and enrich our materia medica.

I hope future drug proving protocols will incorporate modern technology, and collect these ‘enhanced observations’ also and add them to future materia medica compilations. Then, homeopathy will be in a position to utilize these information also in finding appropriate similimum.

I am saying lab investigations should be made part of drug proving protocol, and such information included in materia medica as ‘symptoms’, so that they could be used for finding similimum. That is why I said lab investigations should be part of ‘homeopathic case taking’, not part of ‘homeopathic practice’. I wanted to highlight that difference.

Information obtained from such investigations could be utilized as ‘Objective Symptoms’, I mean.  That means, we can make ‘homeopathic prescriptions’ based on lab investigations also, along with other symptoms

‘Similimum means ‘Similarity of Functional groups’:

To understand the real science behind the phenomena of ‘similia similibus curentur’, ‘drug proving’ and ‘potentization’, we should study drug substances in terms of not only their ‘constituent molecules’, but in terms of ‘functional groups’ and ‘moieties’ of those drug molecules. A drug substance is composed of diverse types of drug molecules. A drug molecule interacts with ‘active groups’ of biological target molecules such as enzymes and receptors using their ‘functional groups’ or ‘moieties’. It is the ‘functional groups’ and ‘moieties’ on the individual drug molecules that decide to which biological molecules they can bind to and produce molecular inhibitions. Different drug molecules with different size and structures, but having same ‘functional group’ or ‘moiety’ can bind to same biological molecules and produce similar molecular errors and similar groups of symptoms. A drug molecule become similimum to a disease when the drug molecule and disease-producing molecule have same functional groups, so that they could bind to same biological targets producing same molecular errors and same symptom groups.

Drug molecules act upon the biological molecules in the organism by binding their ‘functional groups’ to the active groups on the complex biological molecules such as receptors and enzymes. These molecular interactions are determined by the affinity between functional groups or moieties of drug molecules and active sites of biological molecules. Here, the functional groups of drug molecules are called ‘ligands’, and the biological molecules are called ‘targets’. Ligand-target interaction is determined by a peculiar ‘key-lock’ relationship due to complementary configurational affinities.

It is to be specifically noted that same functional group will undergo the same or similar chemical reactions regardless of the size or configuration of of the molecule it is a part of. However, its relative reactivity can be modified by nearby functional groups known as facilitating groups. That means, different types of drug molecules or pathogenic molecules having same functional groups and facilitating groups can bind to same biological molecules, and produce similar molecular inhibitions and symptoms. Homeopathic principle of ‘similimum’ is well explained by this understanding. If a drug molecule can produce symptoms similar to symptoms of a particular disease, it means that the drug molecules and disease-causing molecules have same functional groups on them, by which they bind to same biological molecules. Obviously, similarity of symptoms means similarity of functional groups of pathogenic molecules and drug molecules. To be similimum, the whole molecules need not be similar, but similarity of functional groups is enough.

Potentized drugs would contain the molecular imprints of drug molecules, along with molecular imprints of their functional groups. These molecular imprints will have specific configurational affinity towards any molecule having same functional groups, and can bind and deactivate them.

To be ‘similar’ does not mean pathological molecule and drug molecules should be similar in their ‘whole’ molecular structure. To bind to same targets, similarity of ‘functional groups’ or even a ‘moeity’ is enough. If the adjacent groups that facilitate binding with targets are also same, similarity becomes more perfect. If a drug molecule could produce symptoms similar to a disease, that means the drug molecules contains some functional groups simialr to those of pathogenic molecules that caused the disease. By virtue of these similar functional groups, both pathogenic molecules and drug molecules could bind to same biological targets, producing similar molecular errors and symptoms in the organism.

Molecular imprints of similar functional groups will also be similar. As such, potentized forms of a drug substance can bind and deactivate the pathogenic molecules having similar functional groups. This is the real molecular mechanism of ‘similia similibus curentur’.

Issue of ‘Directions of Cure’:

Some simple observations of Hahnemann and Hering regarding the process of cure were later named by Kent as hering’s laws, and raised to the status of ‘fundamental laws’ of homeopathy. Our teachers, who were mostly kentians, promoted these ‘laws’ as an ‘essential’ aspect of cure, and propagated the idea that every genuine homeopathic cures should ‘obey’ these rules- if not, it will not be considered a ‘genuine’ cure!

The four ‘laws’ now known as ‘herings laws’ are actually some casual observations made by herinh regarding ‘order of cure’ while explaining the demonstrate the homeopathic curative process. No where he said these are ‘fundamental laws’ or ‘essential’ laws. According to available documents and historical evidences, heringr his great contemporaries never mentioned or considered ‘direction of cure’ as a ‘fundamental law’ of homeopathy.

It was ‘KENT’ who later actually called these observations as ‘Herings laws’ and converted these four observations into ‘fundamental laws’ of homeopathic cure. He taught to understand and apply these ‘laws’ in a mechanical way. He taught homeopaths to ‘follow ‘hering laws’ regarding ‘directions of cure’ as one of the ‘fundamental laws’ of homeopathy, similar to ‘similia similibus curentur’.

Kent made homeopaths believe that drug effects that do not agree with these ‘laws’ cannot be considered ‘curative’, and are ‘suppressive’. There are some modern streams of homeopathic practice which rely more upon ‘hering laws’ than ‘similia similibu curentur’ in their methods of therapeutic applications.

Actually, Hahnemann did not seriously work upon those aspects of curative processes which we call ‘directions of cure’, or considered it a decisive factor in homeopathic therapeutics. He made some observations regarding ‘order of cure’. He was more concerned about ‘miasms’ in the management of ‘chronic diseases’, where as Hering did not consider ‘miasms’ at all.

Some modern ‘theoreticians’ have come with new theories by combining ‘hering laws’ and theory of miasms, also mixing up with terms of ‘genetics’ and ‘embryology’ which they propagate as the ‘only’ correct understanding of homeopathy.

Following are the four observations hering used to demonstrate that ‘curative processes happen in a direction just reverse to disease processes’, and later considered by KENT as ‘Hering laws of direction of cure’:

In curative process,

1. Symptoms should disappear in the reverse chronological order of their appearance in disease.
2. Symptoms should travel from internal parts of body to external parts
3. Symptoms should travel from more vital organs to less vital organs.
4. Symptoms should travel from ‘upper’ parts of the body to ‘lower’ parts.

According to those who consider these as the ‘fundamental laws of cure’, any drug effect that happen not in accordance with above laws are ‘suppressive’, and hence not ‘curative’.

‘Curative processes happen in a direction just reverse to disease processes’- that is the sum total of Hering’s observations regarding ‘directions of cure’.The four ‘laws’ now known as ‘herings laws’ are actually the working examples he used to demonstrate this fundamental observation.

It was the later ‘interpreters’ who actually converted these four ‘working’ examples into ‘fundamental laws’ of homeopathic cure. They understood and applied these ‘laws’ in a mechanical way. They taught homeopaths to consider ‘hering laws’ regarding ‘directions of cure’ as one of the ‘fundamental laws’ of homeopathy, similar to ‘similia similibus curentur’. They made homeopaths believe that drug effects that do not agree with these ‘laws’ cannot be considered ‘curative’, and are ‘suppressive’. There are some modern streams of homeopathic practice which rely more upon ‘hering laws’ than ‘similia similibu curentur’ in their methods of therapeutic applications.

According to hering’s observation, natural disease processes always advances from lower parts of the body to upper parts, from less vital to more vital organs and from external to internal organs. More over, all these disease processes advance in a chronological order.

Logically, Hering’s observations only mean that “all genuine ‘curative processes’ should happen in a direction just reverse to disease processes”.

Over-extending and mechanical application of ‘herings laws’ without understanding their exact premises and scientific meaning may lead to grave errors regarding interpretation of curative processes and drug effects.

This phenomenon could be explained in the light of modern scientific understanding of ‘cascading of pathological molecular inhibitions’ and complex dynamics of ‘bio-molecular feed back mechanisms’.

To understand this explanation, one has to equip himself with at least a working knowledge regarding the concepts of modern biochemistry regarding the bio-molecular inhibitions involved in pathology and therapeutics.

Except those diseases which are purely due to errors in genetic substances, and those diseases which are due to genuine deficiency of building materials of biological molecules, all other diseases are considered to be caused by ‘molecular inhibitions’. Pathogenic molecules of endogenous or exogenous origin bind to some biological molecules in the organism, causing ‘molecular inhibitions’ which lead to pathological derangement in associated biochemical pathways. These pathogenic molecules may be of infectious, environmental, nutritional, metabolic, drug-induced, miasmatic or any other origin. Derangements in biochemical pathways are expressed through diverse groups of subjective and objective symptoms. This is the fundamental biochemistry of pathology.

Molecular inhibitions happening in a biological molecule due to the binding of a pathogenic molecule initiates a complex process of ‘cascading of molecular errors’ and ‘bio-feedback mechanisms’ in the organism. Errors happening in a particular biochemical pathway leads to errors in another pathway which is dependant on the first pathway for regular supply of metabolites, which further lead to errors in another pathway. This ‘cascading of molecular errors’ happens through successive stages, which is expressed through new subjective and objective symptoms. This ‘cascading’ is behind what we call ‘advancing of disease’ into new systems and organs, exhibiting ever new groups of associated symptoms. For an observer, this cascading appears in the form of ‘traveling of disease’ from one system into another. Along with these ‘cascading’ of molecular errors, there happens a series of activation and shutting down of complex ‘bio-molecular feedback’ mechanisms also. The phenomenon of ‘advancing of diseases’ should be studied in this scientific perspective of modern biochemistry.

When a molecular inhibition happens in some biological molecule ‘A’ due to binding of a pathogenic molecule ‘a’, it actually stops or decreases some essential molecular conversions that are essential part of a complex biochemical pathway P.  If ‘G’ is the normal ligand of ‘A’, and ‘g’ is the product of biochemical interaction involving ‘A’, the result of this molecular inhibition is that ‘G’ accumulates on one side, and ‘g’ is not available for the next stage of molecular processes. Accumulating ‘P’ may induce a feedback mechanism leading to reduction or stoppage its production itself, or may move to other parts of organism and bind to unwanted molecular targets, initiation a new stream of pathological derangement.

Obviously, ‘travelling’ of disease or ‘advancing’ of disease happens through cascading of molecular errors in various biochemical pathways. Some disease processes may ‘travel’ from ‘external’ to internal organs, some from ‘lower parts’ to upper parts, some from ‘less vital’ parts to ‘more vital’ parts. All this ‘travelling’ is basically decided by the involved biochemical pathways. It would be wrong to generalize these observations in such a way that ‘all diseases travel from exterior to interior, lower parts to higher parts,  and less vital to more vital parts’. It is also wrong to generalize in such a way that ‘curative process always travel from interior to exterior, above downwards, and from vital to less vital parts’. This is mechanical understanding and application of hering’s observations.

Actually, curative processes happen in a direction opposite to the direction of disease process. That depends upon the biochemical pathways involved and the exact dynamics of cascading of molecular inhibitions. Its dynamics is very complex, and should not be interpreted and applied in a mechanistic way. When ‘molecular inhibitions’ underlying the disease processes are systematically removed using molecular imprints, the curative process also would take place in the reverse direction of disease processes.

To sum up, Hering’s observations regarding a ‘directions of disease and cure’ is a valuable one, but it should be studied in the light of modern biochemistry.

Classical homeopaths totally failed to comprehend the biochemistry involved in homeopathic therapeutics, and hence could not interpret the ‘directions of disease and cure’ in relation with the interactions of biochemical pathways.

Fear of ‘Suppressions’:

Fear of ‘suppression of disease’ that may happen from ‘improper’ use of homeopathic drugs is the most prominent symptom of any ‘classical homeopath’, which indicates severe deficiency of scientific knowledge regarding the biochemistry of life, disease and cure. This ‘phobia’ is ‘inherited’ through generations of homeopaths, from ‘teachers’ to ‘students’, and ‘gurus’ to ‘disciples’. Modern ‘Gurus’ spin fanciful ‘theories of suppressions’, write and sell heavy books on their ‘theories’, and fly around the globe to conduct ‘expensive’ seminars to ‘educate’ the homeopathic community for the sole purpose of saving humanity from grave dangers imposed by homeopathic ‘suppressions’.

Those who are severely afflicted with this ‘deficiency syndrome’ will hesitate to prescribe even a single dose of potentized drug to their patient, fearing it may ‘drive in’ the disease from ‘external parts’ to ‘vital’ internal organs if the prescription somehow happens not to be the ‘most appropriate similimum’. They would shudder with fear of dangers of ‘suppression’ if somebody says they have applied some external ointments on eczematous lesion on the skin. According to them, homeopathic drugs are so ‘powerful’ and ‘dangerous’ that an inappropriate or untimely dose of a potentized drug may even kill the patient, or create irreversible disabilities. ‘Better not to prescribe, than prescribing wrongly and causing suppressions’.

In ‘chronic diseases’, hahnemann was talking about the chronic constitutional effects of infectious diseases such as itch, syphilis and gonorrhoea. He thought that these chronic disease dispositions caused by infectious diseases were due to their ‘suppression’ through faulty allopathic medications and external applications. He called these ‘chronic dispositions’ as ‘miasms’. Actually, these chronic dispositions after infectious diseases were not due to any suppression, but the ‘off-target’ effects of antibodies formed against infections. Hahnemann could not understand this ‘antibody factor’ of chronic miasms. That is due to the historical limitations of scientific knowledge available during his period. ‘Historical limitations’ is different from being ‘wrong’.

Modern theories of suppressions are different. They are theorizing about suppressions caused by ‘improper’ application of homeopathic drugs. Those theories are different from what hahnemann considered suppressions.

Theories of suppression as ‘driving in’ of diseases to ‘inner vital organs’ by application of ‘wrong’ drugs is based on an exaggerated application of hering laws and a total misinterpretation of embryology. I was examining thse theoreticalfoundations of modern ‘theory of suppression’. Hering law is over extended, and ’embryological layers’ is mis-interpreted. Logical scrutiny shows that both these theoretical foundations of ‘theory of suppression’ are wrong. That is my point here.

Concept of ‘suppressions’ is based on unscientific understanding of disease, cure, potentization and ‘similia similibus curentur. Scientific awareness is the only way to free homeopaths from the persistent fear of ‘suppressions’, and enable them to make logical prescriptions without any hesitations and forebodings. Understanding the biochemistry of life, disease and cure is essential for this. Homeopaths should realize the exact process of molecular imprinting involved in potentization, and perceive potentized drugs in terms of constituent molecular imprints. They should also learn the molecular mechanism of homeopathic therapeutics as removal of pathological molecular inhibitions by the action of molecular imprints.  Homeopaths would then realize that no potentized homeopathic drugs can make any ‘suppression’ or ‘dangerous consequences’. If the selection of similimum was wrong, it will not act. If the selected drug is ‘partial similimum’, it would give partial cure. In that case, cure can be completed by using additional drugs, which are indicated by totality of remaining symptoms.

Are those ‘Laws’ and ‘Principles’ ‘fundamental’ and immutable?

‘Homeopathy  is taught as a closed system of eternally immutable ‘laws’, ‘rules’, ‘principles’ and ‘methods’ every ‘true’ homeopath is bound to ‘obey’. We hear ‘seven cardinal principles of hahnemann’, ‘hering laws’, ‘kents observations’ and many other ‘theories’ that rule the practice of homeopathy. Anybody violating or thinking beyond these ‘fundamental laws’ are considered to be ‘wrong homeopaths’. And they ask science to explain “every aspect” of homeopathy without “distorting” its “fundamentals”!

We should remember, no ‘masters’ so far knew what really happens during potentization. Nobody so far knew what are the exact active principles of potentized drugs. Nobody so far knew the exact molecular level mechanism by which the active principles of potentized drugs interact with the biological organism and produce a therapeutic effect. Only things our masters actually knew was the objective natural phenomena of ‘likes curing likes’ and ‘high dilution effects’.

Everything else were mere speculations. Speculations based on unscientific philosophy of ‘dynamism’ and ‘vitalism’. All ‘laws’, ‘rules’, ‘methods’ and ‘doctrines’ we consider as ‘cardinal principles of homeopathy evolved from these speculative theories. All ‘directions’ regarding ‘doses’, repetitions’, ‘single drugs’, ‘follow ups’ and everything else were formulated without clearly knowing the substances we are actually dealing with or how they actually work. They were based on misinterpreted ‘experiences’ of ‘stalwarts’ with historically limited scientific knowledge.

Once we acquire scientific knowledge regarding the exact processes involved in potentization, active principles of potentized drugs and the molecular mechanism of their therapeutic action, all the existing ‘methods’, ‘laws’, ‘rules’ and ‘principles’ are bound to change. New ‘principles’ and ‘methods’ will evolve. That means, we will have to discard, change or ‘distort’ many things so far considered as ‘fundamentals’ of homeopathy.

I am talking about ‘principles’ and ‘methods’ of homeopathic practice such as ‘dose’ and ‘repetitions’ on the basis of my scientific understanding of potentization as ‘molecular imprinting’, active principles of potentized drugs as ‘molecular imprints’, and homeopathic therapeutics as removal of biochemical inhibitions. My explanations cannot be expected to be strictly in accordance with what you consider inevitable ‘laws’ of homeopathy.

Acquiring a scientific understanding of the phenomena involved in ‘similia similibus curentur’ and ‘potentization’, and applying that knowledge judiciously for curing the sick- that should be the only ‘fundamental rule’ that guide a homeopath.

‘Likes cures likes’ and ‘high dilution effects’ represent the objective part of homepathy, which are concerned with truthful observations of natural phenomena involved in the process of ‘cure’. This is the strong and rational aspect of homeopathy that have to be preserved, explored and advanced into more and more perfection.

The theoretical explanatory part of homeopathy, which is based on totally unscientific and irrational philosophy of ‘dynamism’ and ‘vitalism’ of eighteenth century europe, as well as the ‘rules’, ‘laws’ and ‘methods’ formulated accordingly, is the real stumbling block that prevents this wonderful therapeutic art from advancing into a scientific medical system.

We have to preserve and strengthen the rational objective aspect of homeopathy, and explain it in terms of modern scientific knowledge. We should show the audacity to discard its irrational and unscientific theoretical parts. Once we understand the real science involved in the phenomena of ‘likes cure likes’ and ‘potentization’, a whole new set of practical ‘rules’ and ‘laws’ would spontaneously evolve.

In the preface to the third edition of ORGANON, Dr Hahnemann made the following statement:

“In this third edition I have not refrained from making any alterations and emendations suggested by increased knowledge and necessitated by further experience.”

This statement is a fitting answer to those ‘dogmatic’ homeopaths who argue nothing could be changed or updated in homeopathy.

Hahenemann advises us not to “refrain” from making “alterations and emendations”, if “suggested by increased knowledge and necessitated by further experience.”

Many homeopaths talk about ‘seven cardinal principles of hahnemann’, and believe that without following these ‘cardinal’ principles one cannot be a ‘true’ homeopath.

Did hahnemann ever say there are ‘seven’ cardinal principles in homeopathy? Kindly verify for references from hahnemann’s original works. When we say homeopaths should ‘follow’ certain ‘cardinal principles of hahnemann’, we should inquire about the original reference where hahnemann said these are the cardinal principles.

Actually hahnemann did not make a ‘list’ of principles. He made some objective observations regarding the phenomenon of ‘cure’, and inferred that an objective ‘law’ is working under this phenomenon. He called it ‘similia similibus curentur’.

While experimenting with smaller and smaller doses of drug substances to avoid the bad effects of crude drugging prevalent in conventional medicine during that period, he noticed that even highly diluted drugs have medicinal effects, even though there existed least chance for medicinal substance to be present in them

Then he took up the task of explaining these two phenomena ( similia similibus curentur and high dilution effects) using the existing scientific knowledge available to him, thereby trying to build up a simple, safe and effective therapeutic system.

Since the scientific knowledge system was in its primitive stage of evolution during that time, it was difficult to explain these observed phenomena using existing tool-kit of science. In the absence of necessary scientific knowledge available for accomplishing this task, he was compelled to speculate using philosophical concepts such as ‘dynamism’ or ‘vitalism’. Actually, ORGANON represents his highly intellectual attempts to explain his fundamental observations regarding phenomena of cure.

In organon, he discussed many things, from ‘vital force theory’ to ‘mesmerism’. That does not mean everything he discussed are ‘cardinal’ principles of homeopathy. If you want to identify such ‘cardinal’ or ‘basic’ things of homeopathy, they are ‘similia similibus curentur’ and ‘potentization’. They are the ‘fundamental objective observations’ of natural phenomena. Everything else is philosophical speculations, which are bound to change as our scientific knowledge advances.

Actually, the ‘seven cardinal principles’ were the invention of some later interpreters- not of hahnemann. Somebody understood homeopathy that way- that is all. You can ‘filter’ any number of ‘cardinal’ principles from hahnemann’s works, according to your perspectives and understandings. If you want to see ‘vital force’ as cardinal principle of homeopathy, somebody else could say ‘mesmerism’ is also a cardinal principle of homeopathy. You can list ‘seven’ or ‘seventy’.

Somebody involved in the making of homeopathic curriculum for Indian universities happened to be influenced by this ‘seven cardinal principles’ and included it in the syllabus. Indian students were taught that to be a ‘true’ homeopath, they should ‘follow’ these ‘seven’ principles. If it was part of your syllabus, somebody should have asked the teachers for original references from hahnemann and verify whether hahnemann did say these ‘seven’ are ‘cardinal principles’ of homeopathy. That is the way inquisitive minds should work and learn more and more deep.

According to my analysis, the only ‘cardinal’ or ‘basic’ things in homeopathy are ‘two’ fundamental observations hahnemann made regarding the objective phenomena of ‘cure’. They are ‘similia similibus curentur’ and ‘potentization’. Everything else is totally unscientific speculations and theorizations made in an attempt to explain these ‘basic’ observations. There is nothing ‘cardinal’ in those observations. It is our duty to explain hahnemann’s ‘fundamental observations’ in terms of modern scientific knowledge system.

I would like to call ‘Similia Similibus Curentur’ and ‘Potentization’ as fundamental ‘observations’ of homeopathy, rather than using the term ‘fundamental principles’. That would be more close to truth.

Hahnemann made two important observations regarding therapeutics 250 years ago:

1. Diseases with specific symptoms can be cured by drugs that can produce similar symptoms in healthy individuals. He called it ‘similia similibus curentur’.
2. When used according to ‘similia similibus curentur’, dug substances can act as powerful therapeutic agents even in high dilutions through a process of serial ‘dilution and succussion’. He called this process as ‘potentization’.

These two are the main ‘observations’ made by Hahnemann, which are known as fundamental principles of Homeopathy.

Hahnemann tried to explain these observations in terms of scientific and philosophical knowledge available to him in that point of time. Organon consists of these theoretical explanations and speculations. Since scientific knowledge was in its primitive stage at that time, Hahnemann’s explanations were bound to bear that limitations. ORGANON contains a lot of theorizations and speculations that do not agree with, or go against modern scientific understanding.

Equipped with modern scientific knowledge and its tools, we are now in a far better position than Samuel Hahnemann to explain the phenomena he observed 250 years ago. Now we can explain ‘similia similibus curentur’ and ‘potentization’ more scientifically, rationally and logically. With full respect the great genius of our master, we should be truthful and bold enough to discard those evidently unscientific theoretical speculations of ORGANON.

These two fundamental observations were based on experiences, experiments and logical evaluations of objective phenomena of nature done by a great intellectual person. but the ‘principles’ he used to explain these objective phenomena were unscientific, obviously due to the limitations of scientific knowledge available to him at that time. We should accept his observations, but judiciously discard or modify his unscientific principles.

Some people consider each and every word uttered by our ‘master’ as ‘fundamental principles’ of homeopathy. Some others would even include the words of other ‘stalwarts’ like Kent, Herring and the like also in the category of ‘fundamental’ principles.

All these ‘theories’ are only philosophical explanations, conjectures, interpretations, opinions and empirical conclusion based on personal experiences of ‘stalwarts’ and ‘masters’. They are not ‘fundamental principles’ of homeopathy.

If you understand the scientific meaning of ‘similia similibus curentur’ and ‘potentization’, and judiciously apply them for curing the patients, you are a ‘true homeopath’, even if you do not ‘follow’ the ‘seven cardinal principles’ invented by unscientific interpreters of hahnemann.

A ‘true’ homeopath is one who understands and applies homeopathy ‘scientifically- not one who learns homeopathy dogmatically and applies it blindly.

The main point I raise here is whether the concept of “seven cardinal principles” originally belongs to hahnemann or his later interpreters. Hahnemann said many things in his books, from ‘similia’ to ‘mesmerism’. Who decided only these ‘seven’ are ‘cardinal’ and others are not? What is the logic behind such a slection? Who did it?

Issue of ‘Drug Relationship’:

Drug relationship is a subject about which most homeo practitioners are very much worried and confused. Some practitioners very much rely upon ‘drug relationships’ even in deciding their treatment protocols. Concepts such as ‘complementary’, ‘inimical’, ‘antidotal’ etc. are frequently utilized in everyday practice. Some doctors even deviate from the theory of similimum, due to their over indulgence with ‘drug relationship’ protocols. When prescribing a drug based on its so-called complementary relationship to the earlier prescriptions, we forget to consider whether it is a similimum by totality of symptoms. Yet, we call it ‘classical’ homeopathy. When searching through the literature and authorities regarding drug relationships, it will be seen that no serious scientific studies have been done on this subject. Most of the drug relationships are proposed by empirical clinical observations of practitioners, and not corroborated by scientific studies or evidences. More over, practitioners who are not much bothered over this relationships between drugs swear that their experiences prove otherwise. Some homeopaths prescribe so-called inimical drugs even simultaneously or alternatingly, and get expected clinical results.

We have already seen during our previous deliberations that in homoeopathic potencies above 12C, there is no chance of drug molecules to exist. These preparations contain only hydrosomes or molecular imprints of constituent molecules of the drug substance subjected to potentization. Molecular imprints are only nanocavities formed by supra-molecular clustering of water and ethyl alcohol. Chemically, they contain only water and ethyl alcohol molecules. Even a given sample of homeopathic potency contains hundreds of types of individual imprints, representing the diverse types of molecules contained in the original drug substance. It is clear that they co-exist without disturbing or influencing each other in anyway, same time preserving their individual properties as molecular imprints of specific drug molecules.

1. This clearly indicates that highly potentized homoeopathic preparations cannot chemically interact with each other, since they contain no drug molecules. Obviously, they are not likely to engage in any mutual interaction within or outside the organism. They can never antidote or destroy each other.
2. Same time, the case of mother tinctures and preparations below 12c potencies may be totally different. They contain crude drug molecules, which can interact with each other due to their chemical properties. The concept of ‘drug relationships’ may be valid in the case of these low potencies. Low potencies may be more active than crude drugs, since they contain free molecules and ions.
3. Low potencies and mother tincture of a drug may antidote higher potencies of same drug, due to the interaction with the hydrosomes which act as counteractive complementary factors to each other.
4. Same way, low potencies and mother tinctures of a drug may antidote higher potencies of another drug that may contain similar constituent molecules, due to the interaction with the hydrosomes having counteractive complementary factors relationship. Obviously, drugs containing similar molecules may have more or less similar symptomatology during drug proving.
5. Higher potencies of a drug may antidote the physiological effects of low potencies and mother tinctures of same drug, due to the interaction with the hydrosomes acting as counteractive complementary factors.
6. Same way, higher potencies of a drug may antidote low potencies and mother tincture of another drug, that may contain similar constituent molecules, due to the interaction with the counteractive complementary factors contained in the higher potencies.

If there is similarity only between certain types of constituent molecules of two drugs, partial antodoting is possible. That means, molecules having configurational similarity only are subjected to antidoting by this way. Such drugs will have partially similar symptomatologies.

We should be aware of the possibility of dangerous chemical interactions that might result between the constituent drug molecules of different drugs, when we mix or administer two or more mother tinctures and low potency preparations together.

Role of ‘key-note symptoms’ in making homeopathic prescriptions:

A keynote symptom is a specific ‘symptom complex’ of ‘accessory symptoms’ that when appears associated with an abnormal basic symptom in a patient, specifically indicates a particular remedy. these keynote ‘symptom complexes’ are constituted by two or more very characteristic ‘accessory symptoms’ belonging to categories such as causations, locations, presentations, sensations, modalities and concomitants.

A Keynote ‘symptom complex’ becomes more useful in practice, when it contains minimum number of ‘accessory symptoms’ and it indicates minimum number of drugs- preferably SINGLE drug. In such cases, that drug could be prescribed very easily, and with full confidence.

Keynote symptom is a symptom, which if present in a patient, will directly lead us to a specific remedy. That symptom will work as a keynote in deciding a prescription for that case.

Most probably, a ‘keynote’ symptom is a ‘symptom complex’ that represents a specific molecular error produced in the organism by a specific pathogenic molecule. When same ‘keynote’ ‘symptom complex’ is also present in a drug, that shows the drug also contains a constituent molecule similar to that pathogenic molecule, which produced similar molecular errors during drug proving. Due to that similarity, molecular imprints of that particular drug molecules can bind specifically to those pathogenic molecules, there by removing the molecular inhibitions they produced in biological molecules.

‘Totality of symptoms’ in a patient means totality of all the diverse types of ‘symptom complexes’ expressed by the patient, representing all the diverse types of molecular errors produced by all the diverse types of pathogenic molecules.

‘Keynote symptom’ in a patient means a particular ‘symptom complex’ expressed by the patient, representing a particular type of molecular error produced by a particular type of pathogenic molecule.

When finding similimum by ‘totality of symptoms’, we are trying to find a drug that contains maximum number of diverse chemical molecules matching to maximum number of diverse pathogenic molecules that produced the diverse types of molecular errors as well as ‘symptom complexes’ in that particular patient.

When finding similimum by keynote method, we are trying to find a particular drug that contains a particular constituent molecule that is similar to a particular pathogenic molecule that produced a particular molecular in the organism and expressed through a particular ‘symptom complex’.

Keynote prescription tries to address a case by identifying a specific molecular error in the patient, where as totality of symptoms tries to address the case by considering maximum number of diverse molecular errors existing in the patient.

In keynote prescriptions, we select a similimum by considering only specific symptom complex representing a specific molecular error in the patient as a standard single unit, and identifying a drug that could produce symptom complex similar to it during drug proving.

Actually, a keynote symptom is a symptom, which if present in a patient, will directly lead us to a specific remedy. That symptom will work as a keynote in deciding a prescription for that case.

Use of Mother Tinctures:

I am not sure regarding the stand of ‘banerji protocols’ regarding the use of mother tinctures. MIT is of the strong conviction that using mother tinctures cannot be considered as genuine homeopathy, for obvious reasons.

We know that many homeopathic practitioners prescribe plenty of mother tinctures and  low potency preparations. They do very successful ‘practice’ also. But, I am a bit suspicious regarding the desirability of using mother tinctures and low potencies, especially in a routine way for long terms.

It may relieve some of the symptoms, of course. But such relief is allopathic- not homeopathic. Chances of emerging new pathological conditions really exist in such a treatment protocol.

We must not forget that the symptomatologies provided in our materia medica give the list of symptoms that can be generated in healthy persons by the use of these drugs in crude form.  Indiscriminate long-term use of mother tinctures containing plant enzymes, poisonous alkaloids, glycosides and various other phyto-chemical ingredients is an  unpardonable  crime even if it is done in the name of homeopathy. The drug molecules and ions contained in these tinctures might give temporary relief  by nutritional supplementation, or competitive relationship to pathological  molecules due to configurational similarity. But it is evident from their symptomatologies  that those molecules and ions are capable of creating dangerous pathological molecular inhibitions in various bio-chemic channels in the organism. We should never forget that the subjective and objective symptoms provided in our material medica were created by the molecular deviations happened in healthy individuals during drug proving. Hence in my opinion, it is ideal to treat patients using potencies above  12c, which do not contain any trace of the drug molecules of the original drug. If our selection of drug is correct, there is no any chance of failure in such a protocol. Other wise, it will have to be considered as identical to Ayurveda, Allopathy or Herbal treatment. Those who indulge in excessive use of mother tinctures, without bothering  about the constituent drug  molecules and their adverse long term impacts on the organism, are more hazardous to human health than our allopathic counterparts. I humbly request them to think over.

From our materia medica works, it may be understoodthat most of  those people who had participated in proving of  Hydrastis Canadensis developed symptoms of gastric ulcer and hyperacidity along with many other deep seated pathological conditions. Doctors who administer large doses of Hydrastis Tincture to relive gastric symptoms as part of homeopathic treatment should note this point . Of course, we may get temporary relief, by the way of competitive relationships with pathological molecules, due to configurational similarity of drug molecules and pathological molecules. The prolonged use of Hydrastis Tincture not only produce the symptoms mentioned in the materia medica,  but may even induce very serious genetic errors to happen. If  hydrastis is the similimum forthe patient, it will be effective in high potencies. This is real homeopathy.

Please do not be provoked when I say that who give Passiflora for inducing sleep, Rauwolfia for lowering blood pressure and Syzijium for high blood sugar in their tincture form, are not practicing ideal Homeopathy even if they may be wellk nown Homeopaths, producing results.  No homeopath with some common sense, who had carefully read the material medica of Alfalfa will dare to prescribe it as tonics to improve the appetite and general health of innocent children. It is evident from its symptomatology that Alfalfa is capable of producing diabetes, bulimia, and upsetting the normal functioning of kidneys.

Please read the provings of calc fluor and calc phos. They were the symptoms produced in healthy individuals by the action of those substances in molecular form. Symptoms cannot be produced without some molecular level changes in the organism. That means, molecular forms of those substances were capable of producing some harmful changes in biological processes. How can you think those drugs will not produce harmful effects in molecular forms. Fact is fact, what ever people think about them, or what are practiced so far.

We should remember that there was no exact knowledge regarding the long term evil effects of many drugs, when many of them were proved and their materia medica prepared. There was least knowledge about the genetic disorders they were likely to produce. It is found in Boecricke Materiamedica that Arsenic Bromide Mother Tincture is indicated for Diebetes. No physician with scientific awareness will even think of prescribing it today.Who will now dare to prescribe Ars iod 3x, Iodum 3x, Sulphur Q, or various compounds of Mercury and Lead only because they are found in our text books of Materia Medica?

We know of homeopaths who make their patients consume for prolonged periods, the mother tinctures of several drugs, including various patented combinations flooding the market in the name of Homeopathy. How can Homeopaths prescribe them without any prick of conscience? Those who love homoeopathy should take urgent initiative to prevent such tendencies either through awareness programs and campaigns, or through stringent legislational procedures.

How the mother tinctures differ from potentized drugs in their mechanism of therapeutic action, and why potentized drugs are more safe and effective than mother tinctures?

Not only potentized drugs, but mother tinctures and crude drugs also can act as ‘similimum’. But the molecular mechanisms of their therapeutic actions and ultimate outcome are fundamentally different from each other.

Drug molecules contained in mother tinctures and crude drugs ‘compete’ with pathogenic molecules having similar molecular configuration in binding to biological molecules and displace them, thereby relieving biological molecules from pathological inhibitions. By this ‘competitive’ relationship to pathogenic molecules, mother tinctures and crude drugs can act as similimum and produce therapeutic results.

‘Molecular imprints’ contained in potentized drugs act by an entirely different molecular mechanism. Molecular imprints binds directly to the pathogenic molecules having configurational affinity and deactivate them, thereby relieving biological molecules from pathological inhibitions. This is the molecular mechanism involved in the therapeutic action of potentized drugs.

Most notable difference is, drug molecules act as similimum by ‘competitive’ relationship toward pathogenic molecules, whereas ‘molecular imprints’ act by ‘complementary’ relationship.

Since crude drugs and mother tinctures contain drug molecules that can act upon biological molecules, they can also bind to various biological targets in the organism. Obviously, there is always chance for creation of new molecular inhibitions and drug-induced pathologies when we use crude drugs and mother tinctures. That is the draw back of using mother tinctures even if they are similimum.

Advantage of potentized drugs is that they do not contain any drug molecules, but only molecular imprints, which are only supra-molecular clusters of water and alcohol molecules. They can act upon pathogenic molecules only, not upon biological molecules. As such, potentized drugs cannot do any further harm to organism.

What will happen when ‘similimum’ is used in crude or ‘molecular’  forms? How their action will be different from that of potentized forms?

A drug is said to be similimum to a case when the symptoms produced by the disease in the patient is similar to the symptoms that drug could produce in a person without any disease. That means, the drug and the ‘disease-causing agents’ contain some ‘chemical molecules’ or ‘functional groups’ that are similar in conformations so that they could bind to similar molecular targets in the organism and produce similar molecular inhibitions that are expressed through similar subjective and objective symptoms.

When we apply ‘molecular forms’ of similimum in the patient, drug molecules compete with pathogenic molecules for binding to the same biological target molecules. According to the dynamics of biochemistry, such a competitive relationship of drug molecules and pathogenic molecules may result in the removal of inhibitions, if the affinity of drug molecules toward biological targets is higher than the affinity of pathogenic molecules. That means, crude forms of similimum may in certain instances cure the disease by competitive molecular mechanism.

It should be noted that the drug molecules cannot remove the molecular inhibitions if the they are overpowered by pathogenic molecules regarding their affinity towards biological targets so that the competition is not effective. This fact explains why crude forms of similimum fail in curing the disease in most occasions.

Another point to be noted that the crude drug substance contain diverse types of chemical molecules that can bind to various unexpected molecular targets in the organism and produce new molecular inhibitions in them. This fact explains the phenomena known as side effects and bad effects of drugs commonly experienced when using molecular forms of drug substances. That is why I keep on saying that using of mother tinctures and low potencies are undesirable and dangerous.

Similimum potentized above 12c contain no drug molecules, but only molecular imprints of drug molecules. When used as similimum, these molecular imprints act as artificial binding sites or artificial locks for the pathogenic molecules having similar functional groups. Due to this conformational affinity, they can selectively bind to the specific pathogenic molecules, and relieve the biological molecules from pathological inhibitions. This is the molecular mechanism involved in the therapeutic action of similimum in potentized forms. Since they do not contain any chemical molecules other than water and ethyl alcohol, they cannot produce any unwanted molecular inhibitions or side effects. That is why potentized drugs are said to be safe.

That is why we say only potentized drugs are genuine homeopathy, and safer than mother tinctures and molecular forms of drugs.

MIT approach makes homeopathic practice more rational and more scientific:

Once you understand and accept the scientific approach towards homeopathy as Molecular Imprints Therapeutics, instantly you start  experiencing the self-confidence it provides, the great empowerment and transformation it brings to your over-all outlook and practice as a homeopath.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, and practice it accordingly, you will realize that your whole erstwhile perceptions of homeopathy is undergoing a wonderful change- your methods, targets and approaches changing radically. You will realize that you are no more a ‘healer’ practicing a ‘belief healing system’,  but a proud scientific medical professional, capable of understanding and scientifically explaining your tools and principles to anybody. Your language becomes scientific, your thoughts become rational and your explanations becomes logical and convincing. You will no more have to talk about miracles, wonders, riddles and mysteries of homeopathy. Experience this change yourselves!

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you would realize that any individual patient coming to you will have diverse types of molecular errors in him, caused by diverse types of endogenous or exogenous pathogenic molecules, and as such, diverse types of molecular imprints will be required to remove all these multitudes of molecular inhibitions to effect a complete cure. In most cases, all these diverse molecular imprints required for the patient will not be available in a ‘single’ drug, and hence, we will have to select more than one drug according to similarity of symptom groups, and apply them simultaneously, alternatingly or serially as decided by the physician. In my opinion, there is no harm even if they are applied together.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, all your confusions over ‘miasms’ could be resolved by perceiving miasms as chronic disease dispositions caused by the off-target actions of antibodies generated against exogenous or endogenous proteins including infectious agents. It would help you in scientifically understanding and treating various types of chronic diseases including auto immune diseases

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you will realize that concepts such as ‘internal essence of drug substance’, ‘dynamic drug energy’, ‘drug personality’ etc are all scientifically baseless, and that the medicinal property of drug substance is decided by the structure and properties of constituent molecules, where as the medicinal properties of potentized drugs are decided by the 3-d configuration of molecular imprints they contain.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you will realize that when applied as similimum, potentized drug does not act as a ‘whole’ unit, but it is the individual constituent ‘molecular imprints’ that independently bind to the pathogenic molecules having configurational affinity, remove pathological molecular inhibitions and cure the disease. You will realize that you need not worry over single/multiple drugs issue any more.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you will realize that during ‘drug proving’, drug substance does not act as a ‘whole’ unit, but it is the individual constituent drug molecules that independently act up on the biological molecules, cause molecular inhibitions and produce symptoms.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you will realize that since molecular imprints do not interact each other, and since they act as individual units when applied as therapeutic agents, there cannot by any harm even if we mix two or more potentized drugs together, or prescribe them simultaneously- they will work.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you will realize that even so-called ‘single drugs’ are not really single, but combinations of diverse types of independent ‘molecular imprints’, representing diverse types of drug molecules, acting as independent units upon pathogenic molecules having configurational affinity and removing molecular inhibitions

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you will realize that ‘molecular imprints’ forms of drugs cannot interact each other, and as such, one cannot antidote another, or act inimical to each other.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you will realize that there is no chance of so-called aggravations, suppressions, provings or any other harm even if ‘wrong’ drug, ‘wrong’ potency or ‘untimely repetitions are used, if you are using only ‘molecular imprints’ forms of drugs.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics, you realize that selecting drug, potency, dose and follow up and getting cure are not a so much complex thing as we are made to believe.

Once you understand and accept homeopathy as Molecular Imprints Therapeutics,you realize no more ‘riddles and mysteries’ remain in homeopathy that could not be explained.

Only Molecular Imprints Therapeutics provides a sound explanation of homeopathy, fitting well to modern science and our every day experiences.

Once the scientific knowledge provided by MIT is incorporated into BANERJI PROTOCOLS as its theoretical foundation and its practical tools further streamlined accordingly, it will become more perfect as a most scientific and rational method of homeopathic practice ever evolved during the whole history of homeopathic practice. Actually, I feel that MIT has its closest practical counterpart in BANERJI PROTOCOLS, and BANERJI PROTOCOLS has its closest theoretical counterpart in MIT.